SG KH20241008 CN 202311543915.2 2023-11-17 成都康弘生物科技有限公司 Chengdu Kanghong Biotechnologies Co.Ltd DOUBLE-TOXIN ANTIBODY-DRUG CONJUGATE AND USE THEREOF 26 5 AA PAT source 1..5 mol_type protein organism synthetic construct NYGMN 17 AA PAT source 1..17 mol_type protein organism synthetic construct WINTYTGEPTYTDDFKG 12 AA PAT source 1..12 mol_type protein organism synthetic construct GGFGSSYWYFDV 11 AA PAT source 1..11 mol_type protein organism synthetic construct KASQDVSIAVA 7 AA PAT source 1..7 mol_type protein organism synthetic construct SASYRYT 10 AA PAT source 1..10 mol_type protein organism synthetic construct QQHYITPLTF 121 AA PAT source 1..121 mol_type protein organism synthetic construct QVQLQQSGSELKKPGASVKVSCKASGYTFTNYGMNWVKQAPGQGLKWMGWINTYTGEPTYTDDFKGRFAFSLDTSVSTAYLQISSLKADDTAVYFCARGGFGSSYWYFDVWGQGSLVTVSS 107 AA PAT source 1..107 mol_type protein organism synthetic construct DIQLTQSPSSLSASVGDRVSITCKASQDVSIAVAWYQQKPGKAPKLLIYSASYRYTGVPDRFSGSGSGTDFTLTISSLQPEDFAVYYCQQHYITPLTFGAGTKVEIK 451 AA PAT source 1..451 mol_type protein organism synthetic construct QVQLQQSGSELKKPGASVKVSCKASGYTFTNYGMNWVKQAPGQGLKWMGWINTYTGEPTYTDDFKGRFAFSLDTSVSTAYLQISSLKADDTAVYFCARGGFGSSYWYFDVWGQGSLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK 214 AA PAT source 1..214 mol_type protein organism synthetic construct DIQLTQSPSSLSASVGDRVSITCKASQDVSIAVAWYQQKPGKAPKLLIYSASYRYTGVPDRFSGSGSGTDFTLTISSLQPEDFAVYYCQQHYITPLTFGAGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 10 AA PAT source 1..10 mol_type protein organism synthetic construct GGSFSGYYWS 16 AA PAT source 1..16 mol_type protein organism synthetic construct EINHSGSTNYNPSLKS 9 AA PAT source 1..9 mol_type protein organism synthetic construct DKWTWYFDL 17 AA PAT source 1..17 mol_type protein organism synthetic construct RSSQSVLYSSSNRNYLA 7 AA PAT source 1..7 mol_type protein organism synthetic construct WASTRES 9 AA PAT source 1..9 mol_type protein organism synthetic construct QQYYSTPRT 117 AA PAT source 1..117 mol_type protein organism synthetic construct QVQLQQWGAGLLKPSETLSLTCAVYGGSFSGYYWSWIRQPPGKGLEWIGEINHSGSTNYNPSLKSRVTISVETSKNQFSLKLSSVTAADTAVYYCARDKWTWYFDLWGRGTLVTVSS 113 AA PAT source 1..113 mol_type protein organism synthetic construct DIEMTQSPDSLAVSLGERATINCRSSQSVLYSSSNRNYLAWYQQNPGQPPKLLIYWASTRESGVPDRFSGSGSGTDFTLTISSLQAEDVAVYYCQQYYSTPRTFGQGTKVEIK 447 AA PAT source 1..447 mol_type protein organism synthetic construct QVQLQQWGAGLLKPSETLSLTCAVYGGSFSGYYWSWIRQPPGKGLEWIGEINHSGSTNYNPSLKSRVTISVETSKNQFSLKLSSVTAADTAVYYCARDKWTWYFDLWGRGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK 220 AA PAT source 1..220 mol_type protein organism synthetic construct DIEMTQSPDSLAVSLGERATINCRSSQSVLYSSSNRNYLAWYQQNPGQPPKLLIYWASTRESGVPDRFSGSGSGTDFTLTISSLQAEDVAVYYCQQYYSTPRTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 20 DNA PAT source 1..20 mol_type other DNA organism synthetic construct atggctacatgagagcggag 19 DNA PAT source 1..19 mol_type other DNA organism synthetic construct cgttgcacctctctggtcc 21 DNA PAT source 1..21 mol_type other DNA organism synthetic construct accaagcagacgcagatcttc 19 DNA PAT source 1..19 mol_type other DNA organism synthetic construct cgccctcgtacacctggat 19 DNA PAT source 1..19 mol_type other DNA organism synthetic construct ctcgctcctctcccacttg 20 DNA PAT source 1..20 mol_type other DNA organism synthetic construct tgaccgggttggttttgatc