WO PCT/CN2024/124097 2024-10-11 234794 1PCWO CN 202311324995.2 2023-10-12 WUXI BIOLOGICS IRELAND LIMITED Lian Dujuan Method For Constructing Vector Pair, and Host Cell and High-Expression Cell Strain 13 124 AA PAT source 1..124 mol_type protein organism Streptoalloteichus hindustanus MAKLTSAVPVLTARDVAGAVEFWTDRLGFSRDFVEDDFAGVVRDDVTLFISAVQDQVVPDNTLAWVWVRGLDELYAEWSEVVSTNFRDASGPAMTEIGEQPWGREFALRDPAGNCVHFVAEEQD 94 AA PAT source 1..94 mol_type protein note artificial sequence organism synthetic construct MAKLTSAVPVLTARDVAGAVEFWTDRLGFSRDFVEDDFAGVVRDDVTLFISAVQDQVVPDNGSGGALKKELQANKKELAQLKWELQALKKELAQ 98 AA PAT source 1..98 mol_type protein note artificial sequence organism synthetic construct MEQLEKKLQALEKKLAQLEWKNQALEKKLAQGSGGTLAWVWVRGLDELYAEWSEVVSTNFRDASGPAMTEIGEQPWGREFALRDPAGNCVHFVAEEQD 94 AA PAT source 1..94 mol_type protein note artificial sequence organism synthetic construct MAKLTSAVPVLTARDVAEAVEFWTDRLGFSRVFVEDDFAGVVRDDVTLFISAVQDQVVPDNGSGGALKKELQANKKELAQLKWELQALKKELAQ 98 AA PAT source 1..98 mol_type protein note artificial sequence organism synthetic construct MEQLEKKLQALEKKLAQLEWKNQALEKKLAQGSGGTQAWVWVRGLDELYAEWSEVVSTNFRDASGPAMTEIVEQPWGREFALRDPAGNCVHFVAEEQD 98 AA PAT source 1..98 mol_type protein note artificial sequence organism synthetic construct MEQLEKKLQALEKKLAQLEWKNQALEKKLAQGGGGGSAKLTSAVPVLTARDVAGAVEFWTDRLGFSRDFVEDDFAGVVRDDVTLFISAVQDQVVPDNT 95 AA PAT source 1..95 mol_type protein note artificial sequence organism synthetic construct MLAWVWVRGLDELYAEWSEVVSTNFRDASGPAMTEIGEQPWGREFALRDPAGNCVHFVAEGGGGGGALKKELQANKKELAQLKWELQALKKELAQ 98 AA PAT source 1..98 mol_type protein note artificial sequence organism synthetic construct MEQLEKKLQALEKKLAQLEWKNQALEKKLAQGGGGGSAKLTSAVPVLTARDVAEAVEFWTDRLGFSRVFVEDDFAGVVRDDVTLFISAVQDQVVPDNT 95 AA PAT source 1..95 mol_type protein note artificial sequence organism synthetic construct MQAWVWVRGLDELYAEWSEVVSTNFRDASGPAMTEIVEQPWGREFALRDPAGNCVHFVAEGGGGGGALKKELQANKKELAQLKWELQALKKELAQ 30 AA PAT source 1..30 mol_type protein note artificial sequence organism synthetic construct EQLEKKLQALEKKLAQLEWKNQALEKKLAQ 29 AA PAT source 1..29 mol_type protein note artificial sequence organism synthetic construct ALKKELQANKKELAQLKWELQALKKELAQ 451 AA PAT source 1..451 mol_type protein note artificial sequence organism synthetic construct EVQLVESGGGLVQPGRSLRLSCAASGFTFDDYAMHWVRQAPGKGLEWVSAITWNSGHIDYADSVEGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCAKVSYLSTASSLDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK 214 AA PAT source 1..214 mol_type protein note artificial sequence organism synthetic construct DIQMTQSPSSLSASVGDRVTITCRASQGIRNYLAWYQQKPGKAPKLLIYAASTLQSGVPSRFSGSGSGTDFTLTISSLQPEDVATYYCQRYNRAPYTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC