LAPCT241064 CN 202311565388.5 2023-11-22 THE UNITED BIO-TECHNOLOGY (HENGQIN) CO., LTD. The United Biotechnology (Hengqin) Co., Ltd. ANTI-IL-4RaANTIBODY OR ANTIGEN-BINDING FRAGMENT THEREOF,AND BISPECIFIC ANTIBODY AND USE THEREOF 60 10 AA PAT source 1..10 mol_type protein organism Artificial Sequence GYTFTTYYIY 17 AA PAT source 1..17 mol_type protein organism Artificial Sequence GSNPSTGGTLDNEKFKT 9 AA PAT source 1..9 mol_type protein organism Artificial Sequence SGRYAPFTY 11 AA PAT source 1..11 mol_type protein organism Artificial Sequence KASQDVSTSVA 7 AA PAT source 1..7 mol_type protein organism Artificial Sequence SASYRFT 9 AA PAT source 1..9 mol_type protein organism Artificial Sequence QHYSTTPFT 17 AA PAT source 1..17 mol_type protein organism Artificial Sequence GSNPSTGGTLENEKFKT 9 AA PAT source 1..9 mol_type protein organism Artificial Sequence VHYSTTPFT 9 AA PAT source 1..9 mol_type protein organism Artificial Sequence SGRYATFTY 17 AA PAT source 1..17 mol_type protein organism Artificial Sequence GSNPSTGGTLFNEKFKT 9 AA PAT source 1..9 mol_type protein organism Artificial Sequence QQYSTTPFT 10 AA PAT source 1..10 mol_type protein organism Artificial Sequence GFTFSSYYMS 17 AA PAT source 1..17 mol_type protein organism Artificial Sequence AINSNGGSTYSPDTVKG 14 AA PAT source 1..14 mol_type protein organism Artificial Sequence RSLLGNHRDWYFDV 11 AA PAT source 1..11 mol_type protein organism Artificial Sequence RASENIYSYLA 7 AA PAT source 1..7 mol_type protein organism Artificial Sequence NAKTLAD 9 AA PAT source 1..9 mol_type protein organism Artificial Sequence LHHYGTPLT 118 AA PAT source 1..118 mol_type protein organism Artificial Sequence QVQLQQPGAELVKPGASMKLSCKASGYTFTTYYIYWVKQRPGQGLEWIGGSNPSTGGTLFNEKFKTKATLTVDKYSSTAYMELSSLTFEDSAVYFCTRSGRYAPFTYWGQGTLVTVSA 107 AA PAT source 1..107 mol_type protein organism Artificial Sequence DIVMTQSHKVLSTSVGDRVIITCKASQDVSTSVAWYQQRPGHSPKLLIYSASYRFTGVPDRFTGSGSGTDFTFTISSVQAEDLAVYNCQQYSTTPFTFGSGTKLEIK 123 AA PAT source 1..123 mol_type protein organism Artificial Sequence DVKLVESGGGLVKLGGSLKLSCAASGFTFSSYYMSWVRQTPEKRLELVAAINSNGGSTYSPDTVKGRFTISRDNAKNTLYLQMSSLKSEDTALYYCARRSLLGNHRDWYFDVWGAGTTVTVSS 107 AA PAT source 1..107 mol_type protein organism Artificial Sequence DIQMTQSPASLSASVGETVTITCRASENIYSYLAWYQQKQGKSPQLLVYNAKTLADGVPSRFSGSGSGTQFSLKINTLQPEDFGSYYCLHHYGTPLTFGAGTKLELK 118 AA PAT source 1..118 mol_type protein organism Artificial Sequence QVQLVQSGAEVKKPGASVKVSCKASGYTFTTYYIYWVRQAPGQGLEWMGGSNPSTGGTLFNEKFKTRVTMTRDTSTSTVYMELSSLRSEDTAVYYCARSGRYAPFTYWGQGTLVTVSS 107 AA PAT source 1..107 mol_type protein organism Artificial Sequence DIQMTQSPSSLSASVGDRVTITCKASQDVSTSVAWYQQKPGKAPKLLIYSASYRFTGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQYSTTPFTFGQGTKLEIK 123 AA PAT source 1..123 mol_type protein organism Artificial Sequence EVQLVESGGGLVKPGGSLRLSCAASGFTFSSYYMSWVRQAPGKGLEWVSAINSNGGSTYSPDTVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCARRSLLGNHRDWYFDVWGQGTTVTVSS 107 AA PAT source 1..107 mol_type protein organism Artificial Sequence DIQMTQSPSSLSASVGDRVTITCRASENIYSYLAWYQQKPGKAPKLLIYNAKTLADGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCLHHYGTPLTFGQGTKLEIK 118 AA PAT source 1..118 mol_type protein organism Artificial Sequence QVQLVQSGAEVKKPGASVKVSCKASGYTFTTYYIYWVRQAPGQGLEWMGGSNPSTGGTLFNEKFKTRVTMTVDKSTSTAYMELSSLRSEDTAVYYCTRSGRYAPFTYWGQGTLVTVSS 107 AA PAT source 1..107 mol_type protein organism Artificial Sequence DIQMTQSPSSLSASVGDRVTITCKASQDVSTSVAWYQQKPGKAPKLLIYSASYRFTGVPSRFSGSGSGTDFTFTISSLQPEDFATYYCQQYSTTPFTFGQGTKLEIK 118 AA PAT source 1..118 mol_type protein organism Artificial Sequence QVQLVQSGAEVKKPGASVKVSCKASGYTFTTYYIYWVRQAPGQGLEWMGGSNPSTGGTLDNEKFKTRVTMTVDKSTSTAYMELSSLRSEDTAVYYCTRSGRYAPFTYWGQGTLVTVSS 107 AA PAT source 1..107 mol_type protein organism Artificial Sequence DIQMTQSPSSLSASVGDRVTITCKASQDVSTSVAWYQQKPGKAPKLLIYSASYRFTGVPSRFSGSGSGTDFTFTISSLQPEDFATYYCQHYSTTPFTFGQGTKLEIK 118 AA PAT source 1..118 mol_type protein organism Artificial Sequence QVQLVQSGAEVKKPGASVKVSCKASGYTFTTYYIYWVRQAPGQGLEWMGGSNPSTGGTLENEKFKTRVTMTVDKSTSTAYMELSSLRSEDTAVYYCTRSGRYAPFTYWGQGTLVTVSS 107 AA PAT source 1..107 mol_type protein organism Artificial Sequence DIQMTQSPSSLSASVGDRVTITCKASQDVSTSVAWYQQKPGKAPKLLIYSASYRFTGVPSRFSGSGSGTDFTFTISSLQPEDFATYYCVHYSTTPFTFGQGTKLEIK 118 AA PAT source 1..118 mol_type protein organism Artificial Sequence QVQLVQSGAEVKKPGASVKVSCKASGYTFTTYYIYWVRQAPGQGLEWMGGSNPSTGGTLENEKFKTRVTMTVDKSTSTAYMELSSLRSEDTAVYYCTRSGRYATFTYWGQGTLVTVSS 107 AA PAT source 1..107 mol_type protein organism Artificial Sequence DIQMTQSPSSLSASVGDRVTITCKASQDVSTSVAWYQQKPGKAPKLLIYSASYRFTGVPSRFSGSGSGTDFTFTISSLQPEDFATYYCVHYSTTPFTFGQGTKLEIK 122 AA PAT source 1..122 mol_type protein organism Artificial Sequence QMQLVESGGGVVQPGRSLRLSCAASGFTFRTYGMHWVRQAPGKGLEWVAVIWYDGSNKHYADSVKGRFTITRDNSKNTLNLQMNSLRAEDTAVYYCARAPQWELVHEAFDIWGQGTMVTVSS 326 AA PAT source 1..326 mol_type protein organism Artificial Sequence ASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSNFGTQTYTCNVDHKPSNTKVDKTVERKCCVECPPCPAPPVAGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVQFNWYVDGVEVHNAKTKPREEQFNSTFRVVSVLTVVHQDWLNGKEYKCKVSNKGLPAPIEKTISKTKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPMLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK 108 AA PAT source 1..108 mol_type protein organism Artificial Sequence SYVLTQPPSVSVAPGQTARITCGGNNLGSKSVHWYQQKPGQAPVLVVYDDSDRPSWIPERFSGSNSGNTATLTISRGEAGDEADYYCQVWDSSSDHVVFGGGTKLTVL 106 AA PAT source 1..106 mol_type protein organism Artificial Sequence GQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPTECS 452 AA PAT source 1..452 mol_type protein organism Artificial Sequence EVQLVESGGGLEQPGGSLRLSCAGSGFTFRDYAMTWVRQAPGKGLEWVSSISGSGGNTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKDRLSITIRPRYYGLDVWGQGTTVTVSSASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTKTYTCNVDHKPSNTKVDKRVESKYGPPCPPCPAPEFLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSQEDPEVQFNWYVDGVEVHNAKTKPREEQFNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKGLPSSIEKTISKAKGQPREPQVYTLPPSQEEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSRLTVDKSRWQEGNVFSCSVMHEALHNHYTQKSLSLSLGK 219 AA PAT source 1..219 mol_type protein organism Artificial Sequence DIVMTQSPLSLPVTPGEPASISCRSSQSLLYSIGYNYLDWYLQKSGQSPQLLIYLGSNRASGVPDRFSGSGSGTDFTLKISRVEAEDVGFYYCMQALQTPYTFGQGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 327 AA PAT source 1..327 mol_type protein organism Artificial Sequence ASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTKTYTCNVDHKPSNTKVDKRVESKYGPPCPPCPAPEFLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSQEDPEVQFNWYVDGVEVHNAKTKPREEQFNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKGLPSSIEKTISKAKGQPREPQVYTLPPSQEEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSRLTVDKSRWQEGNVFSCSVMHEALHNHYTQKSLSLSLGK 107 AA PAT source 1..107 mol_type protein organism Artificial Sequence RTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 122 AA PAT source 1..122 mol_type protein organism Artificial Sequence QMQLVESGGGVVQPGRSLRLSCAASGFTFRTYGMHWVRQAPGKCLEWVAVIWYDGSNKHYADSVKGRFTITRDNSKNTLNLQMNSLRAEDTAVYYCARAPQWELVHEAFDIWGQGTMVTVSS 108 AA PAT source 1..108 mol_type protein organism Artificial Sequence SYVLTQPPSVSVAPGQTARITCGGNNLGSKSVHWYQQKPGQAPVLVVYDDSDRPSWIPERFSGSNSGNTATLTISRGEAGDEADYYCQVWDSSSDHVVFGCGTKLTVL 118 AA PAT source 1..118 mol_type protein organism Artificial Sequence QVQLVQSGAEVKKPGASVKVSCKASGYTFTTYYIYWVRQAPGQCLEWMGGSNPSTGGTLDNEKFKTRVTMTVDKSTSTAYMELSSLRSEDTAVYYCTRSGRYAPFTYWGCGTLVTVSS 107 AA PAT source 1..107 mol_type protein organism Artificial Sequence DIQMTQSPSSLSASVGDRVTITCKASQDVSTSVAWYQQKPGKAPKLLIYSASYRFTGVPSRFSGSGSGTDFTFTISSLQPEDFATYYCQHYSTTPFTFGCGTKLEIK 10 AA PAT source 1..10 mol_type protein organism Artificial Sequence GGGGSGGGGS 20 AA PAT source 1..20 mol_type protein organism Artificial Sequence GGGGSGGGGSGGGGSGGGGS 8 AA PAT source 1..8 mol_type protein organism Artificial Sequence GFTFRTYG 8 AA PAT source 1..8 mol_type protein organism Artificial Sequence IWYDGSNK 14 AA PAT source 1..14 mol_type protein organism Artificial Sequence ARAPQWELVHEAFD 6 AA PAT source 1..6 mol_type protein organism Artificial Sequence NLGSKS 11 AA PAT source 1..11 mol_type protein organism Artificial Sequence QVWDSSSDHVV 448 AA PAT source 1..448 mol_type protein organism Artificial Sequence QMQLVESGGGVVQPGRSLRLSCAASGFTFRTYGMHWVRQAPGKGLEWVAVIWYDGSNKHYADSVKGRFTITRDNSKNTLNLQMNSLRAEDTAVYYCARAPQWELVHEAFDIWGQGTMVTVSSASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSNFGTQTYTCNVDHKPSNTKVDKTVERKCCVECPPCPAPPVAGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVQFNWYVDGVEVHNAKTKPREEQFNSTFRVVSVLTVVHQDWLNGKEYKCKVSNKGLPAPIEKTISKTKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPMLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK 214 AA PAT source 1..214 mol_type protein organism Artificial Sequence SYVLTQPPSVSVAPGQTARITCGGNNLGSKSVHWYQQKPGQAPVLVVYDDSDRPSWIPERFSGSNSGNTATLTISRGEAGDEADYYCQVWDSSSDHVVFGGGTKLTVLGQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPTECS 445 AA PAT source 1..445 mol_type protein organism Artificial Sequence QVQLVQSGAEVKKPGASVKVSCKASGYTFTTYYIYWVRQAPGQGLEWMGGSNPSTGGTLDNEKFKTRVTMTVDKSTSTAYMELSSLRSEDTAVYYCTRSGRYAPFTYWGQGTLVTVSSASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTKTYTCNVDHKPSNTKVDKRVESKYGPPCPPCPAPEFLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSQEDPEVQFNWYVDGVEVHNAKTKPREEQFNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKGLPSSIEKTISKAKGQPREPQVYTLPPSQEEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSRLTVDKSRWQEGNVFSCSVMHEALHNHYTQKSLSLSLGK 214 AA PAT source 1..214 mol_type protein organism Artificial Sequence DIQMTQSPSSLSASVGDRVTITCKASQDVSTSVAWYQQKPGKAPKLLIYSASYRFTGVPSRFSGSGSGTDFTFTISSLQPEDFATYYCQHYSTTPFTFGQGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 703 AA PAT source 1..703 mol_type protein organism Artificial Sequence QMQLVESGGGVVQPGRSLRLSCAASGFTFRTYGMHWVRQAPGKGLEWVAVIWYDGSNKHYADSVKGRFTITRDNSKNTLNLQMNSLRAEDTAVYYCARAPQWELVHEAFDIWGQGTMVTVSSASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSNFGTQTYTCNVDHKPSNTKVDKTVERKCCVECPPCPAPPVAGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVQFNWYVDGVEVHNAKTKPREEQFNSTFRVVSVLTVVHQDWLNGKEYKCKVSNKGLPAPIEKTISKTKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPMLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGKGGGGSGGGGSQVQLVQSGAEVKKPGASVKVSCKASGYTFTTYYIYWVRQAPGQCLEWMGGSNPSTGGTLDNEKFKTRVTMTVDKSTSTAYMELSSLRSEDTAVYYCTRSGRYAPFTYWGQGTLVTVSSGGGGSGGGGSGGGGSGGGGSDIQMTQSPSSLSASVGDRVTITCKASQDVSTSVAWYQQKPGKAPKLLIYSASYRFTGVPSRFSGSGSGTDFTFTISSLQPEDFATYYCQHYSTTPFTFGCGTKLEIK 214 AA PAT source 1..214 mol_type protein organism Artificial Sequence SYVLTQPPSVSVAPGQTARITCGGNNLGSKSVHWYQQKPGQAPVLVVYDDSDRPSWIPERFSGSNSGNTATLTISRGEAGDEADYYCQVWDSSSDHVVFGGGTKLTVLGQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPTECS 705 AA PAT source 1..705 mol_type protein organism Artificial Sequence QVQLVQSGAEVKKPGASVKVSCKASGYTFTTYYIYWVRQAPGQGLEWMGGSNPSTGGTLDNEKFKTRVTMTVDKSTSTAYMELSSLRSEDTAVYYCTRSGRYAPFTYWGQGTLVTVSSASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTKTYTCNVDHKPSNTKVDKRVESKYGPPCPPCPAPEFLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSQEDPEVQFNWYVDGVEVHNAKTKPREEQFNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKGLPSSIEKTISKAKGQPREPQVYTLPPSQEEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSRLTVDKSRWQEGNVFSCSVMHEALHNHYTQKSLSLSLGKGGGGSGGGGSQMQLVESGGGVVQPGRSLRLSCAASGFTFRTYGMHWVRQAPGKCLEWVAVIWYDGSNKHYADSVKGRFTITRDNSKNTLNLQMNSLRAEDTAVYYCARAPQWELVHEAFDIWGQGTMVTVSSGGGGSGGGGSGGGGSGGGGSSYVLTQPPSVSVAPGQTARITCGGNNLGSKSVHWYQQKPGQAPVLVVYDDSDRPSWIPERFSGSNSGNTATLTISRGEAGDEADYYCQVWDSSSDHVVFGCGTKLTVL 214 AA PAT source 1..214 mol_type protein organism Artificial Sequence DIQMTQSPSSLSASVGDRVTITCKASQDVSTSVAWYQQKPGKAPKLLIYSASYRFTGVPSRFSGSGSGTDFTFTISSLQPEDFATYYCQHYSTTPFTFGQGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC