B3583PC00 EP 21306229.2 2021-09-08 UNIVERSITE DE STRASBOURG Dominique BAGNARD TRANSMEMBRANE PEPTIDIC ANTAGONISTS OF PLEXIN A1 AND THEIR THERAPEUTIC USES 119 29 AA PAT REGION 1..29 note MTP-PlexA1 source 1..29 mol_type protein organism synthetic construct TLPAIVGIGGGGGLLLLVIVAVLIAYKRK 16 AA PAT REGION 1..16 note antagonistic peptide SITE 1 note MISC_FEATURE - Xaa is G or S SITE 2 note MISC_FEATURE - Xaa is I or G or L SITE 3 note MISC_FEATURE - Xaa is G or V REGION 6..7 note MISC_FEATURE - Xaa is G or V SITE 8 note MISC_FEATURE - Xaa is L or E SITE 11 note MISC_FEATURE - Xaa is L or E SITE 15 note MISC_FEATURE - Xaa is A or E SITE 16 note MISC_FEATURE - BOUND AT THE C TERM TO CterpolyE source 1..16 mol_type protein organism synthetic construct XXXGGXXXLLXVIVXV 17 AA PAT REGION 1..17 note ANTAGONISTIC PEPTIDE SITE 1 note MISC_FEATURE - Xaa is V or T SITE 2 note MISC_FEATURE - Xaa is G or S SITE 3 note MISC_FEATURE - Xaa is I or G or L SITE 4 note MISC_FEATURE - Xaa is G or V REGION 7..8 note MISC_FEATURE - Xaa is G or V SITE 9 note MISC_FEATURE - Xaa is L or E SITE 12 note MISC_FEATURE - Xaa is L or E SITE 16 note MISC_FEATURE - Xaa is A or E SITE 17 note MISC_FEATURE - Bound at the C term to CterpokyE source 1..17 mol_type protein organism synthetic construct XXXXGGXXXLLXVIVXV 18 AA PAT REGION 1..18 note antagonistic peptide SITE 1 note MISC_FEATURE - Xaa is I or L SITE 2 note MISC_FEATURE - Xaa is V or T SITE 3 note MISC_FEATURE - Xaa is G or S SITE 4 note MISC_FEATURE - Xaa is I or G or L SITE 5 note MISC_FEATURE - Xaa is V or G REGION 8..9 note MISC_FEATURE - Xaa is V or G SITE 10 note MISC_FEATURE - Xaa is L or E REGION 10 note MISC_FEATURE - Xaa is L or E SITE 13 note misc_feature - Xaa can be any naturally occurring amino acid SITE 17 note MISC_FEATURE - Xaa is A or E SITE 18 note MISC_FEATURE - Bound at the C term to CterpolyE source 1..18 mol_type protein organism synthetic construct XXXXXGGXXXLLXVIVXV 19 AA PAT REGION 1..19 note antagonistic peptide SITE 1 note MISC_FEATURE - Xaa is A or V SITE 2 note MISC_FEATURE - Xaa is I or L SITE 3 note MISC_FEATURE - Xaa is V or T SITE 4 note MISC_FEATURE - Xaa is G or S SITE 5 note MISC_FEATURE - Xaa is I or G or L SITE 6 note MISC_FEATURE - Xaa is G or V REGION 9..10 note MISC_FEATURE - Xaa is G or V SITE 11 note MISC_FEATURE - Xaa is L or E SITE 14 note MISC_FEATURE - Xaa is L or E SITE 18 note MISC_FEATURE - Xaa is A or E SITE 19 note MISC_FEATURE - Bound at the C term to CterpolyE source 1..19 mol_type protein organism synthetic construct XXXXXXGGXXXLLXVIVXV 20 AA PAT REGION 1..20 note antagonistic peptide SITE 1 note MISC_FEATURE - Xaa is P or I SITE 2 note MISC_FEATURE - Xaa is A or V SITE 3 note MISC_FEATURE - Xaa is I or L SITE 4 note MISC_FEATURE - Xaa is V or T SITE 5 note MISC_FEATURE - Xaa is G or S SITE 6 note MISC_FEATURE - Xaa is I or G or L SITE 7 note MISC_FEATURE - Xaa is G or V REGION 10..11 note MISC_FEATURE - Xaa is G or V SITE 12 note MISC_FEATURE - Xaa is L or E SITE 15 note MISC_FEATURE - Xaa is L or E SITE 19 note MISC_FEATURE - Xaa is A or E SITE 20 note MISC_FEATURE - Bound at the C term to CterpolyE source 1..20 mol_type protein organism synthetic construct XXXXXXXGGXXXLLXVIVXV 21 AA PAT REGION 1..21 note antagonistic peptide SITE 1 note MISC_FEATURE - Xaa is I or L SITE 2 note MISC_FEATURE - Xaa is P or I SITE 3 note MISC_FEATURE - Xaa is A or V SITE 4 note MISC_FEATURE - Xaa is I or L SITE 5 note MISC_FEATURE - Xaa is V or T SITE 6 note MISC_FEATURE - Xaa is G or S SITE 7 note MISC_FEATURE - Xaa is I or G or L SITE 8 note MISC_FEATURE - Xaa is G or V REGION 11..12 note MISC_FEATURE - Xaa is G or V SITE 13 note MISC_FEATURE - Xaa is L or E SITE 16 note MISC_FEATURE - Xaa is L or E SITE 20 note MISC_FEATURE - Xaa is A or E SITE 21 note MISC_FEATURE - Bound at the C term to CterpolyE source 1..21 mol_type protein organism synthetic construct XXXXXXXXGGXXXLLXVIVXV 22 AA PAT REGION 1..22 note antagonistic peptide SITE 2 note MISC_FEATURE - Xaa is I or L SITE 3 note MISC_FEATURE - Xaa is P or I SITE 4 note MISC_FEATURE - Xaa is A or V SITE 5 note MISC_FEATURE - Xaa is I or L SITE 6 note MISC_FEATURE - Xaa is V or T SITE 7 note MISC_FEATURE - Xaa is G or S SITE 8 note MISC_FEATURE - Xaa is I or G or L SITE 9 note MISC_FEATURE - Xaa is G or V REGION 12..13 note MISC_FEATURE - Xaa is G or V SITE 14 note MISC_FEATURE - Xaa is L or E SITE 17 note MISC_FEATURE - Xaa is L or E SITE 21 note MISC_FEATURE - Xaa is A or E SITE 22 note MISC_FEATURE - Bound at the C term to CterpolyE source 1..22 mol_type protein organism synthetic construct TXXXXXXXXGGXXXLLXVIVXV 28 AA PAT REGION 1..28 note antagonistic peptide SITE 1 note MISC_FEATURE - Xaa is G or S SITE 2 note MISC_FEATURE - Xaa is I or G or L SITE 3 note MISC_FEATURE - Xaa is G or V REGION 6..7 note MISC_FEATURE - Xaa is G or V SITE 8 note MISC_FEATURE - Xaa is L or E SITE 11 note MISC_FEATURE - Xaa is L or E SITE 17 note MISC_FEATURE - Xaa is A or LI SITE 19 note MISC_FEATURE - Xaa is E or D source 1..28 mol_type protein organism synthetic construct SITE 20 note Xaa is D or E SITE 21 note Xaa is D, E, or is absent SITE 22 note Xaa is D, E, or is absent SITE 23 note Xaa is D, E or is absent SITE 24 note Xaa is D, E, or is absent SITE 25 note Xaa is D, E, or is absent SITE 26 note Xaa is D, E, or is absent SITE 27 note Xaa is D, E, or is absent SITE 28 note Xaa is D, E, or is absent XXXGGXXXLLXVIVEVXYXXXXXXXXXX 26 AA PAT REGION 1..26 note antagonistic peptide SITE 4 note MISC_FEATURE - Xaa is G or S source 1..26 mol_type protein organism synthetic construct AITXLVGGVGLLLEVIVEVAYEEEEE 24 AA PAT REGION 1..24 note antagonistic peptide SITE 2 note MISC_FEATURE - Xaa is G or S source 1..24 mol_type protein organism synthetic construct TXLVGGVGLLLEVIVEVAYEEEEE 23 AA PAT REGION 1..23 note antagonistic peptide SITE 1 note MISC_FEATURE - Xaa is G or S source 1..23 mol_type protein organism synthetic construct XLVGGVGLLLEVIVEVAYEEEEE 30 AA PAT REGION 1..30 note antagonistic peptide SITE 7 note MISC_FEATURE - Xaa is G or S source 1..30 mol_type protein organism synthetic construct TLPAIVXIGGGGGELLLVIVEVLIYEEEEE 29 AA PAT REGION 1..29 note antagonistic peptide SITE 7 note misc_feature - Xaa can be any naturally occurring amino acid source 1..29 mol_type protein organism synthetic construct TLPAITXLVGGVGLLLEVIVEVAYEEEEE 29 AA PAT REGION 1..29 note antagonistic peptide SITE 7 note MISC_FEATURE - Xaa is G or S source 1..29 mol_type protein organism synthetic construct TLPAIVXIGGGVVLLLEVIVEVAYEEEEE 26 AA PAT REGION 1..26 note KVASIR source 1..26 mol_type protein organism synthetic construct AITGLVGGVGLLLEVIVEVAYEEEEE 24 AA PAT REGION 1..24 note GERD source 1..24 mol_type protein organism synthetic construct TGLVGGVGLLLEVIVEVAYEEEEE 23 AA PAT REGION 1..23 note THRUD source 1..23 mol_type protein organism synthetic construct GLVGGVGLLLEVIVEVAYEEEEE 30 AA PAT REGION 1..30 note RATI source 1..30 mol_type protein organism synthetic construct TLPAIVGIGGGGGELLLVIVEVLIYEEEEE 29 AA PAT REGION 1..29 note GUNGNIR source 1..29 mol_type protein organism synthetic construct TLPAITGLVGGVGLLLEVIVEVAYEEEEE 29 AA PAT REGION 1..29 note MIMMING source 1..29 mol_type protein organism synthetic construct TLPAIVSIGGGVVLLLEVIVEVAYEEEEE 000 000 000 000 000 15 AA PAT REGION 1..15 note antagonistic peptide SITE 1 note MISC_FEATURE - Bound at the N term to NterGp SITE 1 note MISC_FEATURE - Xaa is L or I SITE 2 note MISC_FEATURE - Xaa is P or I SITE 3 note MISC_FEATURE - Xaa is A or V SITE 4 note MISC_FEATURE - Xaa is I or L SITE 5 note MISC_FEATURE - Xaa is V or T SITE 6 note MISC_FEATURE - Xaa is G or S SITE 7 note MISC_FEATURE - Xaa is I or G or L SITE 8 note MISC_FEATURE - Xaa is G or V REGION 11..12 note MISC_FEATURE - Xaa is G or V SITE 13 note MISC_FEATURE - Xaa is L or E source 1..15 mol_type protein organism synthetic construct XXXXXXXXGGXXXLL 16 AA PAT REGION 1..16 note antagonistic peptide SITE 1 note MISC_FEATURE - Bound at the N term to NterGp SITE 1 note MISC_FEATURE - Xaa is L or I SITE 2 note MISC_FEATURE - Xaa is P or I SITE 3 note MISC_FEATURE - Xaa is A or V SITE 4 note MISC_FEATURE - Xaa is I or L SITE 5 note MISC_FEATURE - Xaa is V or T SITE 6 note MISC_FEATURE - Xaa is G or S SITE 7 note MISC_FEATURE - Xaa is I or G or L SITE 8 note MISC_FEATURE - Xaa is G or V REGION 11..12 note MISC_FEATURE - Xaa is G or V SITE 13 note MISC_FEATURE - Xaa is L or E SITE 16 note MISC_FEATURE - Xaa is L or E source 1..16 mol_type protein organism synthetic construct XXXXXXXXGGXXXLLX 17 AA PAT REGION 1..17 note antagonistic peptide SITE 1 note MISC_FEATURE - Bound at the N term to NterGp SITE 1 note MISC_FEATURE - Xaa is L or I SITE 2 note MISC_FEATURE - Xaa is P or I SITE 3 note MISC_FEATURE - Xaa is A or V SITE 4 note MISC_FEATURE - Xaa is I or L SITE 5 note MISC_FEATURE - Xaa is V or T SITE 6 note MISC_FEATURE - Xaa is G or S SITE 7 note MISC_FEATURE - Xaa is I or G or L SITE 8 note MISC_FEATURE - Xaa is G or V REGION 11..12 note MISC_FEATURE - Xaa is G or V SITE 13 note MISC_FEATURE - Xaa is L or E SITE 16 note MISC_FEATURE - Xaa is L or E source 1..17 mol_type protein organism synthetic construct XXXXXXXXGGXXXLLXV 18 AA PAT REGION 1..18 note antagonistic peptide SITE 1 note MISC_FEATURE - Bound at the N term to NterGp SITE 1 note MISC_FEATURE - Xaa is L or I SITE 2 note MISC_FEATURE - Xaa is P or I SITE 3 note MISC_FEATURE - Xaa is A or V SITE 4 note MISC_FEATURE - Xaa is I or L SITE 5 note MISC_FEATURE - Xaa is V or T SITE 6 note MISC_FEATURE - Xaa is G or S SITE 7 note MISC_FEATURE - Xaa is I or G or L SITE 8 note MISC_FEATURE - Xaa is G or V REGION 11..12 note MISC_FEATURE - Xaa is G or V SITE 13 note MISC_FEATURE - Xaa is L or E SITE 16 note MISC_FEATURE - Xaa is L or E source 1..18 mol_type protein organism synthetic construct XXXXXXXXGGXXXLLXVI 19 AA PAT REGION 1..19 note antagonistic peptide SITE 1 note MISC_FEATURE - Bound at the N ter to NterGp SITE 1 note MISC_FEATURE - Xaa is L or I SITE 2 note MISC_FEATURE - Xaa is P or I SITE 3 note MISC_FEATURE - Xaa is A or V SITE 4 note MISC_FEATURE - Xaa is I or L SITE 5 note MISC_FEATURE - Xaa is V or T SITE 6 note MISC_FEATURE - Xaa is G or S SITE 7 note MISC_FEATURE - Xaa is I or G or L SITE 8 note MISC_FEATURE - Xaa is G or V REGION 11..12 note MISC_FEATURE - Xaa is G or V SITE 13 note MISC_FEATURE - Xaa is L or E SITE 16 note MISC_FEATURE - Xaa is L or E source 1..19 mol_type protein organism synthetic construct XXXXXXXXGGXXXLLXVIV 20 AA PAT REGION 1..20 note antagonistic peptide SITE 1 note MISC_FEATURE - Bound at the N term to NterGp SITE 1 note MISC_FEATURE - Xaa is L or I SITE 2 note MISC_FEATURE - Xaa is P or I SITE 3 note MISC_FEATURE - Xaa is A or V SITE 4 note MISC_FEATURE - Xaa is I or L SITE 5 note MISC_FEATURE - Xaa is V or T SITE 6 note MISC_FEATURE - Xaa is G or S SITE 7 note MISC_FEATURE - Xaa is I or G or L SITE 8 note MISC_FEATURE - Xaa is G or V REGION 11..12 note MISC_FEATURE - Xaa is G or V SITE 13 note MISC_FEATURE - Xaa is L or E SITE 16 note MISC_FEATURE - Xaa is L or E SITE 20 note MISC_FEATURE - Xaa is A or E source 1..20 mol_type protein organism synthetic construct XXXXXXXXGGXXXLLXVIVX 21 AA PAT REGION 1..21 note antagonistic peptide SITE 1 note MISC_FEATURE - Bound at the N term to NterGp SITE 1 note MISC_FEATURE - Xaa is L or I SITE 2 note MISC_FEATURE - Xaa is P or I SITE 3 note MISC_FEATURE - Xaa is A or V SITE 4 note MISC_FEATURE - Xaa is I or L SITE 5 note MISC_FEATURE - Xaa is V or T SITE 6 note MISC_FEATURE - Xaa is G or S SITE 7 note MISC_FEATURE - Xaa is I or G or L SITE 8 note MISC_FEATURE - Xaa is G or V REGION 11..12 note MISC_FEATURE - Xaa is G or V SITE 13 note MISC_FEATURE - Xaa is L or E SITE 16 note MISC_FEATURE - Xaa is L or E SITE 20 note MISC_FEATURE - Xaa is A or E source 1..21 mol_type protein organism synthetic construct XXXXXXXXGGXXXLLXVIVXV 22 AA PAT REGION 1..22 note antagonistic peptide SITE 1 note MISC_FEATURE - Bound at the N term to NterGp SITE 1 note MISC_FEATURE - Xaa is L or I SITE 2 note MISC_FEATURE - Xaa is P or I SITE 3 note MISC_FEATURE - Xaa is A or V SITE 4 note MISC_FEATURE - Xaa is I or L SITE 5 note MISC_FEATURE - Xaa is V or T SITE 6 note MISC_FEATURE - Xaa is G or S SITE 7 note MISC_FEATURE - Xaa is I or G or L SITE 8 note MISC_FEATURE - Xaa is G or V REGION 11..12 note MISC_FEATURE - Xaa is G or V SITE 13 note MISC_FEATURE - Xaa is L or E SITE 16 note MISC_FEATURE - Xaa is L or E SITE 20 note MISC_FEATURE - Xaa is A or E source 1..22 mol_type protein organism synthetic construct XXXXXXXXGGXXXLLXVIVXVL 23 AA PAT REGION 1..23 note antagonistic peptide SITE 1 note MISC_FEATURE - Bound at the N term to NterGp SITE 1 note MISC_FEATURE - Xaa is L or I SITE 2 note MISC_FEATURE - Xaa is P or I SITE 3 note MISC_FEATURE - Xaa is A or V SITE 4 note MISC_FEATURE - Xaa is I or L SITE 5 note MISC_FEATURE - Xaa is V or T SITE 6 note MISC_FEATURE - Xaa is G or S SITE 7 note MISC_FEATURE - Xaa is I or G or L SITE 8 note MISC_FEATURE - Xaa is G or V REGION 11..12 note MISC_FEATURE - Xaa is G or V SITE 13 note MISC_FEATURE - Xaa is L or E SITE 16 note MISC_FEATURE - Xaa is L or E SITE 20 note MISC_FEATURE - Xaa is A or E source 1..23 mol_type protein organism synthetic construct XXXXXXXXGGXXXLLXVIVXVLI 21 AA PAT REGION 1..21 note antagonistic peptide SITE 1 note MISC_FEATURE - Xaa is A or V SITE 2 note MISC_FEATURE - Xaa is I or L SITE 3 note MISC_FEATURE - Xaa is V or T SITE 4 note MISC_FEATURE - Xaa is G or S SITE 5 note MISC_FEATURE - Xaa is I or G or L SITE 6 note MISC_FEATURE - Xaa is G or V REGION 9..10 note MISC_FEATURE - Xaa is G or V SITE 11 note MISC_FEATURE - Xaa is L or E SITE 14 note MISC_FEATURE - Xaa is L or E SITE 18 note MISC_FEATURE - Xaa is A or E SITE 21 note MISC_FEATURE - Bound at the C term to CterGp source 1..21 mol_type protein organism synthetic construct XXXXXXGGXXXLLXVIVXVLI 20 AA PAT REGION 1..20 note antagonistic peptide SITE 1 note MISC_FEATURE - Xaa is I or L SITE 2 note MISC_FEATURE - Xaa is V or T SITE 3 note MISC_FEATURE - Xaa is G or S SITE 4 note MISC_FEATURE - Xaa is I or G or L SITE 5 note MISC_FEATURE - Xaa is G or V REGION 8..9 note MISC_FEATURE - Xaa is G or V SITE 10 note MISC_FEATURE - Xaa is L or E SITE 13 note MISC_FEATURE - Xaa is L or E SITE 17 note MISC_FEATURE - Xaa is A or E SITE 20 note MISC_FEATURE - Bound at the C term to CterGp source 1..20 mol_type protein organism synthetic construct XXXXXGGXXXLLXVIVXVLI 19 AA PAT REGION 1..19 note antagonistic peptide SITE 1 note MISC_FEATURE - Xaa is V or T SITE 2 note MISC_FEATURE - Xaa is G or S SITE 3 note MISC_FEATURE - Xaa is I or G or L SITE 4 note MISC_FEATURE - Xaa is G or V REGION 7..8 note MISC_FEATURE - Xaa is G or V SITE 9 note MISC_FEATURE - Xaa is L or E SITE 12 note MISC_FEATURE - Xaa is L or E SITE 16 note MISC_FEATURE - Xaa is A or E SITE 19 note MISC_FEATURE - Bound at the C term to CterGp source 1..19 mol_type protein organism synthetic construct XXXXGGXXXLLXVIVXVLI 18 AA PAT REGION 1..18 note antagonistic peptide SITE 1 note MISC_FEATURE - Xaa is G or S SITE 2 note MISC_FEATURE - Xaa is I or G or L SITE 3 note MISC_FEATURE - Xaa is G or V REGION 6..7 note MISC_FEATURE - Xaa is G or V SITE 8 note MISC_FEATURE - Xaa is L or E SITE 11 note MISC_FEATURE - Xaa is L or E SITE 15 note MISC_FEATURE - Xaa is A or E source 1..18 mol_type protein organism synthetic construct XXXGGXXXLLXVIVXVLI 18 AA PAT REGION 1..18 note antagonistic peptide SITE 10 note MISC_FEATURE - Xaa is G or S source 1..18 mol_type protein organism synthetic construct KGDWLPAITXLVGGVGLL 18 AA PAT REGION 1..18 note antagonistic peptide SITE 10 note MISC_FEATURE - Xaa is G or S source 1..18 mol_type protein organism synthetic construct KGDWLPAIVXIGGGVVLL 18 AA PAT REGION 1..18 note antagonistic peptide SITE 10 note MISC_FEATURE - Xaa is G or S source 1..18 mol_type protein organism synthetic construct KGDWIPALVXGGGGGGLL 18 AA PAT REGION 1..18 note antagonistic peptide SITE 10 note MISC_FEATURE - Xaa is G or S source 1..18 mol_type protein organism synthetic construct KGDWLPALVXIGGGVGLL 18 AA PAT REGION 1..18 note antagonistic peptide SITE 10 note MISC_FEATURE - Xaa is G or S source 1..18 mol_type protein organism synthetic construct KGDWIPALVXLGGGGGLL 14 AA PAT REGION 1..14 note antagonistic peptide SITE 10 note MISC_FEATURE - Xaa is G or S source 1..14 mol_type protein organism synthetic construct KGDWLIAIVXIGGG 14 AA PAT REGION 1..14 note antagonistic peptide SITE 10 note MISC_FEATURE - Xaa is G or S source 1..14 mol_type protein organism synthetic construct KGDWLPVIVXIGGG 18 AA PAT REGION 1..18 note antagonistic peptide SITE 10 note MISC_FEATURE - Xaa is G or S source 1..18 mol_type protein organism synthetic construct KGDWLPAIVXIGGGGGLL 17 AA PAT REGION 1..17 note antagonistic peptide SITE 10 note MISC_FEATURE - Xaa is G or S source 1..17 mol_type protein organism synthetic construct KGDWLPAIVXIGGGGGL 16 AA PAT REGION 1..16 note antagonistic peptide SITE 10 note MISC_FEATURE - Xaa is G or S source 1..16 mol_type protein organism synthetic construct KGDWLPAIVXIGGGGG 15 AA PAT REGION 1..15 note antagonistic peptide SITE 10 note MISC_FEATURE - Xaa is G or S source 1..15 mol_type protein organism synthetic construct KGDWLPAIVXIGGGG 14 AA PAT REGION 1..14 note antagonistic peptide SITE 10 note MISC_FEATURE - Xaa is G or S source 1..14 mol_type protein organism synthetic construct KGDWLPAIVXIGGG 18 AA PAT REGION 1..18 note BALDR source 1..18 mol_type protein organism synthetic construct KGDWLPAITGLVGGVGLL 18 AA PAT REGION 1..18 note FREYR source 1..18 mol_type protein organism synthetic construct KGDWLPAIVSIGGGVVLL 18 AA PAT REGION 1..18 note BRAGI source 1..18 mol_type protein organism synthetic construct KGDWIPALVGGGGGGGLL 18 AA PAT REGION 1..18 note NJORD source 1..18 mol_type protein organism synthetic construct KGDWLPALVSIGGGVGLL 18 AA PAT REGION 1..18 note ULLR source 1..18 mol_type protein organism synthetic construct KGDWIPALVGLGGGGGLL 14 AA PAT REGION 1..14 note SKOLL source 1..14 mol_type protein organism synthetic construct KGDWLIAIVGIGGG 14 AA PAT REGION 1..14 note HATI source 1..14 mol_type protein organism synthetic construct KGDWLPVIVGIGGG 18 AA PAT REGION 1..18 note plexA1-S2 source 1..18 mol_type protein organism synthetic construct KGDWLPAIVGIGGGGGLL 17 AA PAT REGION 1..17 note FJALAR source 1..17 mol_type protein organism synthetic construct KGDWLPAIVGIGGGGGL 16 AA PAT REGION 1..16 note GALAR source 1..16 mol_type protein organism synthetic construct KGDWLPAIVGIGGGGG 15 AA PAT REGION 1..15 note IVALDI source 1..15 mol_type protein organism synthetic construct KGDWLPAIVGIGGGG 14 AA PAT REGION 1..14 note ALVISS source 1..14 mol_type protein organism synthetic construct KGDWLPAIVGIGGG 29 AA PAT REGION 1..29 note SURTR source 1..29 mol_type protein organism synthetic construct TLPVIGVIVLVGSAVLELIAEGVYEEEEE 29 AA PAT REGION 1..29 note HODR source 1..29 mol_type protein organism synthetic construct TLPAIGVITLVGLGVLELVAEGVYEEEEE 18 AA PAT REGION 1..18 note GULLVEIG source 1..18 mol_type protein organism synthetic construct KGDWLPAIVSIGGAVVLL 18 AA PAT REGION 1..18 note SKIRNIR source 1..18 mol_type protein organism synthetic construct KGDWLPAIVGIGGSVVLL 13 AA PAT REGION 1..13 note RATATOSK source 1..13 mol_type protein organism synthetic construct KGDWLPAIVGIGG 19 AA PAT REGION 1..19 note plexA1-S1 source 1..19 mol_type protein organism synthetic construct KGDWTLPAIVGIGGGGGLL 17 AA PAT REGION 1..17 note BROKK source 1..17 mol_type protein organism synthetic construct KGDWPAIVGIGGGGGLL 15 AA PAT REGION 1..15 note EITRI source 1..15 mol_type protein organism synthetic construct KGDWIVGIGGGGGLL 31 AA PAT REGION 1..31 note DRAUPNIR source 1..31 mol_type protein organism synthetic construct TLPAIVGIGGGGGLLLEVIVEVLIAYEEEEE 29 AA PAT REGION 1..29 note MJOLLNIR source 1..29 mol_type protein organism synthetic construct TLPAITGLVGGVGLLVEVAVEIAYEEEEE 13 AA PAT REGION 1..13 note PLP139-151 fragment source 1..13 mol_type protein organism synthetic construct HSLGKWLGHPDKF 21 AA PAT REGION 1..21 note MOG35-55 fragment source 1..21 mol_type protein organism synthetic construct MEVGWYRSPFSRVVHLYRNGK 5 AA PAT REGION 1..5 note CterGp source 1..5 mol_type protein organism synthetic construct AYKRK 5 AA PAT REGION 1..5 note CterGp source 1..5 mol_type protein organism synthetic construct AYKKR 5 AA PAT REGION 1..5 note CterGp source 1..5 mol_type protein organism synthetic construct AYKRR 5 AA PAT REGION 1..5 note CterGp source 1..5 mol_type protein organism synthetic construct AYRRK 5 AA PAT REGION 1..5 note CterGp source 1..5 mol_type protein organism synthetic construct AYRKK 29 AA PAT REGION 1..29 note ODIN source 1..29 mol_type protein organism synthetic construct KRKYAILVAVIVLLLLGVGGGIGVIAPLT 5 AA PAT REGION 1..5 note Part of second domain source 1..5 mol_type protein organism synthetic construct LPAIT 5 AA PAT REGION 1..5 note Part of second domain source 1..5 mol_type protein organism synthetic construct LPAIV 5 AA PAT REGION 1..5 note part of second domain source 1..5 mol_type protein organism synthetic construct IPALV 5 AA PAT REGION 1..5 note part of second domain source 1..5 mol_type protein organism synthetic construct LPALV 5 AA PAT REGION 1..5 note part of second domain source 1..5 mol_type protein organism synthetic construct LIAIV 5 AA PAT REGION 1..5 note part of second domain source 1..5 mol_type protein organism synthetic construct LPVIV 13 AA PAT REGION 1..13 note part of second domain source 1..13 mol_type protein organism synthetic construct GGLLLLVIVAVLI 7 AA PAT REGION 1..7 note CterpolyE source 1..7 mol_type protein organism synthetic construct AYEEEEE 8 AA PAT REGION 1..8 note CterpolyE source 1..8 mol_type protein organism synthetic construct LIYEEEEE 11 AA PAT REGION 1..11 note part of second domain source 1..11 mol_type protein organism synthetic construct VGLLLEVIVEV 10 AA PAT REGION 1..10 note part of second domain source 1..10 mol_type protein organism synthetic construct GGELLLVIVE 11 AA PAT REGION 1..11 note part of second domain source 1..11 mol_type protein organism synthetic construct VVLLLEVIVEV 30 AA PAT source 1..30 mol_type protein organism synthetic construct TLPAITGVVVGGVGLLLEVIVEVAYEEEEE 29 AA PAT source 1..29 mol_type protein organism synthetic construct TLPAITGLVVGVGLLLEVIVEVAYEEEEE 28 AA PAT source 1..28 mol_type protein organism synthetic construct TLPAITGLVGGVGLLLEVIVEVAYEEEE 27 AA PAT source 1..27 mol_type protein organism synthetic construct TLPAITGLVGGVGLLLEVIVEVAYEEE 26 AA PAT source 1..26 mol_type protein organism synthetic construct TLPAITGLVGGVGLLLEVIVEVAYEE 29 AA PAT source 1..29 mol_type protein organism synthetic construct TLPAITGLVGGVGLLLEVIVEVAYDDDDD 29 AA PAT source 1..29 mol_type protein organism synthetic construct TLPAITGLVGGVVLLLEVIVEVAYEEEEE 29 AA PAT source 1..29 mol_type protein organism synthetic construct TLPAITGLVGGVGLVLEVIVEVAYEEEEE 29 AA PAT source 1..29 mol_type protein organism synthetic construct TLPAITGLVGGVGLLLVVIVEVAYEEEEE 29 AA PAT source 1..29 mol_type protein organism synthetic construct TLPAITGLVGGVGLLLEVVVEVAYEEEEE 29 AA PAT source 1..29 mol_type protein organism synthetic construct TLPAITGLVGGVGLLLEVIVVVAYEEEEE 29 AA PAT source 1..29 mol_type protein organism synthetic construct NON_STD 1..29 note D amino acids TLPAITGLVGGVGLLLEVIVEVVYEEEEE 29 AA PAT source 1..29 mol_type protein organism synthetic construct EEEEEYAVEVIVELLLGVGGVLGTIAPLT 26 AA PAT source 1..26 mol_type protein organism synthetic construct TLPAITGLVGGVGLLLEVIVEVAYDD 29 AA PAT source 1..29 mol_type protein organism synthetic construct TLPAITGLVGGVGLLLEVIVEVAYDEDED 23 AA PAT source 1..23 mol_type protein organism synthetic construct TGLVGGVGLLLEVIVEVAYEEEE 22 AA PAT source 1..22 mol_type protein organism synthetic construct TGLVGGVGLLLEVIVEVAYEEE 29 AA PAT source 1..29 mol_type protein organism synthetic construct MOD_RES 1 note D-Threonine TLPAITGLVGGVGLLLEVIVEVAYEEEEE 29 AA PAT source 1..29 mol_type protein organism synthetic construct MOD_RES 21 note D-glutamic acid TLPAITGLVGGVGLLLEVIVEVAYEEEEE 29 AA PAT source 1..29 mol_type protein organism synthetic construct TLPAITGLVGGVGLLVEVIVEVAYEEEEE 29 AA PAT source 1..29 mol_type protein organism synthetic construct TLPAITGLVGGVGLLLEVAVEVAYEEEEE 29 AA PAT source 1..29 mol_type protein organism synthetic construct TLPAITGLVGGVGLLLEVIVEIAYEEEEE 4 AA PAT source 1..4 mol_type protein organism synthetic construct KGDW 11 AA PAT source 1..11 mol_type protein organism synthetic construct VGLLVEVIVEV 11 AA PAT source 1..11 mol_type protein organism synthetic construct VGLVLEVIVEV 28 AA PAT source 1..28 mol_type protein organism synthetic construct SITE 1 note X is G or S SITE 6..7 note X is G or V SITE 8 note X is L or E SITE 10 note X is L or V SITE 11 note X is L or E SITE 19..20 note X is D or E SITE 21..28 note X is D, E or is absent XLVGGXXXLXXVIVEVAYXXXXXXXXXX