26C80749 CN 202311515509.5 2023-11-14 SIMCERE ZAIMING PHARMACEUTICAL CO., LTD. LIGAND-DRUG CONJUGATE, LINKER FOR CONJUGATION, AND USE THEREOF 22 120 AA PAT source 1..120 mol_type protein organism synthetic construct EVQLVESGGGLVQPGGSLRLSCAASGFNIKDTYIHWVRQAPGKGLEWVARIYPTNGYTRYADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCSRWGGDGFYAMDYWGQGTLVTVSS 107 AA PAT source 1..107 mol_type protein organism synthetic construct DIQMTQSPSSLSASVGDRVTITCRASQDVNTAVAWYQQKPGKAPKLLIYSASFLYSGVPSRFSGSRSGTDFTLTISSLQPEDFATYYCQQHYTTPPTFGQGTKVEIK 330 AA PAT source 1..330 mol_type protein organism synthetic construct ASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK 107 AA PAT source 1..107 mol_type protein organism synthetic construct RTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 5 AA PAT source 1..5 mol_type protein organism synthetic construct DTYIH 17 AA PAT source 1..17 mol_type protein organism synthetic construct RIYPTNGYTRYADSVKG 11 AA PAT source 1..11 mol_type protein organism synthetic construct WGGDGFYAMDY 11 AA PAT source 1..11 mol_type protein organism synthetic construct RASQDVNTAVA 7 AA PAT source 1..7 mol_type protein organism synthetic construct SASFLYS 9 AA PAT source 1..9 mol_type protein organism synthetic construct QQHYTTPPT 454 AA PAT source 1..454 mol_type protein organism synthetic construct QVQLVQSGAEVKKPGSSVKVSCKASGGTFSDNDFSWVRQAPGQGLEWMGAIVAVFRTETYAQKFQDRVKITADISTRTTYMELSSLRSEDTAVYYCARRLMSAISGPGAPLLMWGQGTLVTVSSASTKGPSVCPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSVDKTHTCPPCPAPEFEGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPASIEKTISKAKGQPREPQVYTLPPCREEMTKNQVSLWCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK 446 AA PAT source 1..446 mol_type protein organism synthetic construct QVQLVQSGAEVKKPGASVKVSCKASGYTFTDYYIHWVRQATGQGLEWMGWMNPNSGNTGYAQKFQGRVTMTRDTSISTAYMELSSLRSEDTAVYYCARGQGYTHSWGQGTMVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCDKTHTCPPCPAPEFEGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPASIEKTISKAKGQPREPQVCTLPPSREEMTKNQVSLSCAVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLVSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK 217 AA PAT source 1..217 mol_type protein organism synthetic construct QSALTQPRSVSGSPGQSVTISCTGTSSDVGGYNYVSWYQQHPGKAPKLMIYDVSKRPSGVPDRFSGSKSGNTASLTISGLQAEDEADYYCSSYTSSDTLEIFGGGTKLTVLGQPKAAPSVTLFPPCSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPTEVS 214 AA PAT source 1..214 mol_type protein organism synthetic construct DIQMTQSPSTLSASVGDRVTITCRASEGIYHWLAWYQQKPGKAPKLLIYKASSLASGVPSRFSGSGSGTEFTLTISSLQPDDFATYYCQQYSNYPPTFGGGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 117 AA PAT source 1..117 mol_type protein organism synthetic construct EVQLVQSGAEVKKPGSSVKVSCKASGYTFTNYWMHWVRQAPGQGLEWMGDIDPSHSETHYTQKFKDRVTITVDKSTSTAYMELSSLRSEDTAVYYCARGDLGRFDYWGQGTTVTVSS 111 AA PAT source 1..111 mol_type protein organism synthetic construct DIQMTQSPSSLSASVGDRVTITCRASESVSIHGTHLMHWYQQKPGKPPKLLIYAASNLESGVPSRFSGSGSETDFTFTISSLQPEDIATYYCQQSFEDPWTFGGGTKVEIK 5 AA PAT source 1..5 mol_type protein organism synthetic construct NYWMH 17 AA PAT source 1..17 mol_type protein organism synthetic construct DIDPSHSETHYTQKFKD 8 AA PAT source 1..8 mol_type protein organism synthetic construct GDLGRFDY 15 AA PAT source 1..15 mol_type protein organism synthetic construct RASESVSIHGTHLMH 7 AA PAT source 1..7 mol_type protein organism synthetic construct AASNLES 9 AA PAT source 1..9 mol_type protein organism synthetic construct QQSFEDPWT