US 40848.0112WOU1 US 63/286,476 2021-12-06 REGENERON PHARMACEUTICALS, INC. ANTAGONIST ANTI-NPR1 ANTIBODIES AND METHODS OF USE THEREOF 78 360 DNA PAT source 1..360 mol_type other DNA organism synthetic construct gaggtgcagctggtggagtctgggggaggcttggtacagccgggggggtccctgagactctcctgtgcagcctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggtagtggtactaatacatactacgcagactccgtgaagggccggttcaccatctccaacgacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaattacgatattttgactggtcattcctttgaatactggggccagggaaccctggtcaccgtctcctca 120 AA PAT source 1..120 mol_type protein organism synthetic construct EVQLVESGGGLVQPGGSLRLSCAASGFTFSSYAMSWVRQAPGKGLEWVSTISGSGTNTYYADSVKGRFTISNDNSKNTLYLQMNSLRAEDTAVYYCANYDILTGHSFEYWGQGTLVTVSS 24 DNA PAT source 1..24 mol_type other DNA organism synthetic construct ggattcacctttagcagctatgcc 8 AA PAT source 1..8 mol_type protein organism synthetic construct GFTFSSYA 24 DNA PAT source 1..24 mol_type other DNA organism synthetic construct attagtggtagtggtactaataca 8 AA PAT source 1..8 mol_type protein organism synthetic construct ISGSGTNT 39 DNA PAT source 1..39 mol_type other DNA organism synthetic construct gcgaattacgatattttgactggtcattcctttgaatac 13 AA PAT source 1..13 mol_type protein organism synthetic construct ANYDILTGHSFEY 321 DNA PAT source 1..321 mol_type other DNA organism synthetic construct gccatccagatgacccagtctccatcctccctgtctgcatctgtaggagacagagtcaccatcacttgccgggcaagtcagggcattagaaatgatttaggctggtatcagcagaaaccagggaaagcccctgaactcctaatctatgctgcatccaggttaccaagtggggtcccattaaggttcagcggcagtggatctggcacagatttcactctcaccatcagcagcctgcagcctgaagatgttgcaacttattactgtctacaagattacaattacccattcactttcggccctgggaccaaagtggatatcaaa 107 AA PAT source 1..107 mol_type protein organism synthetic construct AIQMTQSPSSLSASVGDRVTITCRASQGIRNDLGWYQQKPGKAPELLIYAASRLPSGVPLRFSGSGSGTDFTLTISSLQPEDVATYYCLQDYNYPFTFGPGTKVDIK 18 DNA PAT source 1..18 mol_type other DNA organism synthetic construct cagggcattagaaatgat 6 AA PAT source 1..6 mol_type protein organism synthetic construct QGIRND 000 000 27 DNA PAT source 1..27 mol_type other DNA organism synthetic construct ctacaagattacaattacccattcact 9 AA PAT source 1..9 mol_type protein organism synthetic construct LQDYNYPFT 1344 DNA PAT source 1..1344 mol_type other DNA organism synthetic construct gaggtgcagctggtggagtctgggggaggcttggtacagccgggggggtccctgagactctcctgtgcagcctctggattcacctttagcagctatgccatgagctgggtccgccaggctccagggaaggggctggagtgggtctcaactattagtggtagtggtactaatacatactacgcagactccgtgaagggccggttcaccatctccaacgacaattccaagaacacgttgtatctgcaaatgaacagcctgagagccgaggacacggccgtatattactgtgcgaattacgatattttgactggtcattcctttgaatactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcaggcgccctgaccagcggcgtgcacaccttcccggctgtcctacagtcctcaggactctactccctcagcagcgtggtgaccgtgccctccagcagcttgggcacgaagacctacacctgcaacgtagatcacaagcccagcaacaccaaggtggacaagagagttgagtccaaatatggtcccccatgcccaccctgcccagcacctgagttcctggggggaccatcagtcttcctgttccccccaaaacccaaggacactctcatgatctcccggacccctgaggtcacgtgcgtggtggtggacgtgagccaggaagaccccgaggtccagttcaactggtacgtggatggcgtggaggtgcataatgccaagacaaagccgcgggaggagcagttcaacagcacgtaccgtgtggtcagcgtcctcaccgtcctgcaccaggactggctgaacggcaaggagtacaagtgcaaggtctccaacaaaggcctcccgtcctccatcgagaaaaccatctccaaagccaaagggcagccccgagagccacaggtgtacaccctgcccccatcccaggaggagatgaccaagaaccaggtcagcctgacctgcctggtcaaaggcttctaccccagcgacatcgccgtggagtgggagagcaatgggcagccggagaacaactacaagaccacgcctcccgtgctggactccgacggctccttcttcctctacagcaggctcaccgtggacaagagcaggtggcaggaggggaatgtcttctcatgctccgtgatgcatgaggctctgcacaaccactacacacagaagtccctctccctgtctctgggtaaatga 447 AA PAT source 1..447 mol_type protein organism synthetic construct EVQLVESGGGLVQPGGSLRLSCAASGFTFSSYAMSWVRQAPGKGLEWVSTISGSGTNTYYADSVKGRFTISNDNSKNTLYLQMNSLRAEDTAVYYCANYDILTGHSFEYWGQGTLVTVSSASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTKTYTCNVDHKPSNTKVDKRVESKYGPPCPPCPAPEFLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSQEDPEVQFNWYVDGVEVHNAKTKPREEQFNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKGLPSSIEKTISKAKGQPREPQVYTLPPSQEEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSRLTVDKSRWQEGNVFSCSVMHEALHNHYTQKSLSLSLGK 645 DNA PAT source 1..645 mol_type other DNA organism synthetic construct gccatccagatgacccagtctccatcctccctgtctgcatctgtaggagacagagtcaccatcacttgccgggcaagtcagggcattagaaatgatttaggctggtatcagcagaaaccagggaaagcccctgaactcctaatctatgctgcatccaggttaccaagtggggtcccattaaggttcagcggcagtggatctggcacagatttcactctcaccatcagcagcctgcagcctgaagatgttgcaacttattactgtctacaagattacaattacccattcactttcggccctgggaccaaagtggatatcaaacgaactgtggctgcaccatctgtcttcatcttcccgccatctgatgagcagttgaaatctggaactgcctctgttgtgtgcctgctgaataacttctatcccagagaggccaaagtacagtggaaggtggataacgccctccaatcgggtaactcccaggagagtgtcacagagcaggacagcaaggacagcacctacagcctcagcagcaccctgacgctgagcaaagcagactacgagaaacacaaagtctacgcctgcgaagtcacccatcagggcctgagctcgcccgtcacaaagagcttcaacaggggagagtgttag 214 AA PAT source 1..214 mol_type protein organism synthetic construct AIQMTQSPSSLSASVGDRVTITCRASQGIRNDLGWYQQKPGKAPELLIYAASRLPSGVPLRFSGSGSGTDFTLTISSLQPEDVATYYCLQDYNYPFTFGPGTKVDIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 360 DNA PAT source 1..360 mol_type other DNA organism synthetic construct gaggtgcagctggtggagtctgggggaggcttggtacagcctggggggtccctgagactctcctgtgcagcctctggattctcctttgtcagctatgtcatgggctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattagtggaagtcttacgaacacatactacgcagaccccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgcatattactgtgtgacctacgatattttgactggtcatctctttgactactggggccagggaaccctggtcaccgtctcctca 120 AA PAT source 1..120 mol_type protein organism synthetic construct EVQLVESGGGLVQPGGSLRLSCAASGFSFVSYVMGWVRQAPGKGLEWVSSISGSLTNTYYADPVKGRFTISRDNSKNTLYLQMNSLRAEDTAAYYCVTYDILTGHLFDYWGQGTLVTVSS 24 DNA PAT source 1..24 mol_type other DNA organism synthetic construct ggattctcctttgtcagctatgtc 8 AA PAT source 1..8 mol_type protein organism synthetic construct GFSFVSYV 24 DNA PAT source 1..24 mol_type other DNA organism synthetic construct attagtggaagtcttacgaacaca 8 AA PAT source 1..8 mol_type protein organism synthetic construct ISGSLTNT 39 DNA PAT source 1..39 mol_type other DNA organism synthetic construct gtgacctacgatattttgactggtcatctctttgactac 13 AA PAT source 1..13 mol_type protein organism synthetic construct VTYDILTGHLFDY 321 DNA PAT source 1..321 mol_type other DNA organism synthetic construct gccatccagatgacccagtctccatcctccctgtctgcatctgtaggagacagagtcaccatcacttgccggtcaagtcagggcattagaaatgattttggctggtatcagcagaaaccagggaaagcccctaaactcctgatctatgctgcatccagattacaaagtggggtcccatcaaggttcagcggcagtggatctggcacagatttcactctcaccatcaacaacctgcagcctgaagattttgcaacttattactgtctccaagattacacttacccattcactttcggccctgggaccaaagtggatatcaaa 107 AA PAT source 1..107 mol_type protein organism synthetic construct AIQMTQSPSSLSASVGDRVTITCRSSQGIRNDFGWYQQKPGKAPKLLIYAASRLQSGVPSRFSGSGSGTDFTLTINNLQPEDFATYYCLQDYTYPFTFGPGTKVDIK 27 DNA PAT source 1..27 mol_type other DNA organism synthetic construct ctccaagattacacttacccattcact 9 AA PAT source 1..9 mol_type protein organism synthetic construct LQDYTYPFT 1344 DNA PAT source 1..1344 mol_type other DNA organism synthetic construct gaggtgcagctggtggagtctgggggaggcttggtacagcctggggggtccctgagactctcctgtgcagcctctggattctcctttgtcagctatgtcatgggctgggtccgccaggctccagggaaggggctggagtgggtctcaagtattagtggaagtcttacgaacacatactacgcagaccccgtgaagggccggttcaccatctccagagacaattccaagaacacgctgtatctgcaaatgaacagcctgagagccgaggacacggccgcatattactgtgtgacctacgatattttgactggtcatctctttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcaggcgccctgaccagcggcgtgcacaccttcccggctgtcctacagtcctcaggactctactccctcagcagcgtggtgaccgtgccctccagcagcttgggcacgaagacctacacctgcaacgtagatcacaagcccagcaacaccaaggtggacaagagagttgagtccaaatatggtcccccatgcccaccctgcccagcacctgagttcctggggggaccatcagtcttcctgttccccccaaaacccaaggacactctcatgatctcccggacccctgaggtcacgtgcgtggtggtggacgtgagccaggaagaccccgaggtccagttcaactggtacgtggatggcgtggaggtgcataatgccaagacaaagccgcgggaggagcagttcaacagcacgtaccgtgtggtcagcgtcctcaccgtcctgcaccaggactggctgaacggcaaggagtacaagtgcaaggtctccaacaaaggcctcccgtcctccatcgagaaaaccatctccaaagccaaagggcagccccgagagccacaggtgtacaccctgcccccatcccaggaggagatgaccaagaaccaggtcagcctgacctgcctggtcaaaggcttctaccccagcgacatcgccgtggagtgggagagcaatgggcagccggagaacaactacaagaccacgcctcccgtgctggactccgacggctccttcttcctctacagcaggctcaccgtggacaagagcaggtggcaggaggggaatgtcttctcatgctccgtgatgcatgaggctctgcacaaccactacacacagaagtccctctccctgtctctgggtaaatga 447 AA PAT source 1..447 mol_type protein organism synthetic construct EVQLVESGGGLVQPGGSLRLSCAASGFSFVSYVMGWVRQAPGKGLEWVSSISGSLTNTYYADPVKGRFTISRDNSKNTLYLQMNSLRAEDTAAYYCVTYDILTGHLFDYWGQGTLVTVSSASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTKTYTCNVDHKPSNTKVDKRVESKYGPPCPPCPAPEFLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSQEDPEVQFNWYVDGVEVHNAKTKPREEQFNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKGLPSSIEKTISKAKGQPREPQVYTLPPSQEEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSRLTVDKSRWQEGNVFSCSVMHEALHNHYTQKSLSLSLGK 645 DNA PAT source 1..645 mol_type other DNA organism synthetic construct gccatccagatgacccagtctccatcctccctgtctgcatctgtaggagacagagtcaccatcacttgccggtcaagtcagggcattagaaatgattttggctggtatcagcagaaaccagggaaagcccctaaactcctgatctatgctgcatccagattacaaagtggggtcccatcaaggttcagcggcagtggatctggcacagatttcactctcaccatcaacaacctgcagcctgaagattttgcaacttattactgtctccaagattacacttacccattcactttcggccctgggaccaaagtggatatcaaacgaactgtggctgcaccatctgtcttcatcttcccgccatctgatgagcagttgaaatctggaactgcctctgttgtgtgcctgctgaataacttctatcccagagaggccaaagtacagtggaaggtggataacgccctccaatcgggtaactcccaggagagtgtcacagagcaggacagcaaggacagcacctacagcctcagcagcaccctgacgctgagcaaagcagactacgagaaacacaaagtctacgcctgcgaagtcacccatcagggcctgagctcgcccgtcacaaagagcttcaacaggggagagtgttag 214 AA PAT source 1..214 mol_type protein organism synthetic construct AIQMTQSPSSLSASVGDRVTITCRSSQGIRNDFGWYQQKPGKAPKLLIYAASRLQSGVPSRFSGSGSGTDFTLTINNLQPEDFATYYCLQDYTYPFTFGPGTKVDIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 360 DNA PAT source 1..360 mol_type other DNA organism synthetic construct caggtccagctggtacagtctggggctgaggtgaagaagcctggggcctcagtgaaggtttcctgcaaggcatctggatacaccttcaccagctattatatacactgggtgcgacaggcccctggacaagggcttgagtggatgggaataatcagccctagtgatggttacacaagctacgcacagaacttccagggcagagtcaccatgaccagggacacgtccacgaacacagtctacatggacctgagcagcctgagatctgaggacacggccatgttttactgtgcgagaaatgatcctctgaccacagtcgcccttgactactggggccagggaaccctggtcaccgtctcctca 120 AA PAT source 1..120 mol_type protein organism synthetic construct QVQLVQSGAEVKKPGASVKVSCKASGYTFTSYYIHWVRQAPGQGLEWMGIISPSDGYTSYAQNFQGRVTMTRDTSTNTVYMDLSSLRSEDTAMFYCARNDPLTTVALDYWGQGTLVTVSS 24 DNA PAT source 1..24 mol_type other DNA organism synthetic construct ggatacaccttcaccagctattat 8 AA PAT source 1..8 mol_type protein organism synthetic construct GYTFTSYY 24 DNA PAT source 1..24 mol_type other DNA organism synthetic construct atcagccctagtgatggttacaca 8 AA PAT source 1..8 mol_type protein organism synthetic construct ISPSDGYT 39 DNA PAT source 1..39 mol_type other DNA organism synthetic construct gcgagaaatgatcctctgaccacagtcgcccttgactac 13 AA PAT source 1..13 mol_type protein organism synthetic construct ARNDPLTTVALDY 321 DNA PAT source 1..321 mol_type other DNA organism synthetic construct gccatccagatgacccagtctccatcctccctgtctgcatctgtaggagacagagtcaccatcacttgccgggcaagtcagggcattagatatgatttaggctggtttcagcagaaaccagggaaagcccctaaactcctgatccatgctgcatccagtttacaaagtggggtcccatcaaggttcagcggcagtggatctggcacagatttcactctcaccatcagcagcctgcagcctgaagattttgcaacttattactgtctacaagactacaattacccgttcacttttggccaggggaccaagctggagatcaaa 107 AA PAT source 1..107 mol_type protein organism synthetic construct AIQMTQSPSSLSASVGDRVTITCRASQGIRYDLGWFQQKPGKAPKLLIHAASSLQSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCLQDYNYPFTFGQGTKLEIK 18 DNA PAT source 1..18 mol_type other DNA organism synthetic construct cagggcattagatatgat 6 AA PAT source 1..6 mol_type protein organism synthetic construct QGIRYD 27 DNA PAT source 1..27 mol_type other DNA organism synthetic construct ctacaagactacaattacccgttcact 1344 DNA PAT source 1..1344 mol_type other DNA organism synthetic construct caggtccagctggtacagtctggggctgaggtgaagaagcctggggcctcagtgaaggtttcctgcaaggcatctggatacaccttcaccagctattatatacactgggtgcgacaggcccctggacaagggcttgagtggatgggaataatcagccctagtgatggttacacaagctacgcacagaacttccagggcagagtcaccatgaccagggacacgtccacgaacacagtctacatggacctgagcagcctgagatctgaggacacggccatgttttactgtgcgagaaatgatcctctgaccacagtcgcccttgactactggggccagggaaccctggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcaggcgccctgaccagcggcgtgcacaccttcccggctgtcctacagtcctcaggactctactccctcagcagcgtggtgaccgtgccctccagcagcttgggcacgaagacctacacctgcaacgtagatcacaagcccagcaacaccaaggtggacaagagagttgagtccaaatatggtcccccatgcccaccctgcccagcacctgagttcctggggggaccatcagtcttcctgttccccccaaaacccaaggacactctcatgatctcccggacccctgaggtcacgtgcgtggtggtggacgtgagccaggaagaccccgaggtccagttcaactggtacgtggatggcgtggaggtgcataatgccaagacaaagccgcgggaggagcagttcaacagcacgtaccgtgtggtcagcgtcctcaccgtcctgcaccaggactggctgaacggcaaggagtacaagtgcaaggtctccaacaaaggcctcccgtcctccatcgagaaaaccatctccaaagccaaagggcagccccgagagccacaggtgtacaccctgcccccatcccaggaggagatgaccaagaaccaggtcagcctgacctgcctggtcaaaggcttctaccccagcgacatcgccgtggagtgggagagcaatgggcagccggagaacaactacaagaccacgcctcccgtgctggactccgacggctccttcttcctctacagcaggctcaccgtggacaagagcaggtggcaggaggggaatgtcttctcatgctccgtgatgcatgaggctctgcacaaccactacacacagaagtccctctccctgtctctgggtaaatga 447 AA PAT source 1..447 mol_type protein organism synthetic construct QVQLVQSGAEVKKPGASVKVSCKASGYTFTSYYIHWVRQAPGQGLEWMGIISPSDGYTSYAQNFQGRVTMTRDTSTNTVYMDLSSLRSEDTAMFYCARNDPLTTVALDYWGQGTLVTVSSASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTKTYTCNVDHKPSNTKVDKRVESKYGPPCPPCPAPEFLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSQEDPEVQFNWYVDGVEVHNAKTKPREEQFNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKGLPSSIEKTISKAKGQPREPQVYTLPPSQEEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSRLTVDKSRWQEGNVFSCSVMHEALHNHYTQKSLSLSLGK 645 DNA PAT source 1..645 mol_type other DNA organism synthetic construct gccatccagatgacccagtctccatcctccctgtctgcatctgtaggagacagagtcaccatcacttgccgggcaagtcagggcattagatatgatttaggctggtttcagcagaaaccagggaaagcccctaaactcctgatccatgctgcatccagtttacaaagtggggtcccatcaaggttcagcggcagtggatctggcacagatttcactctcaccatcagcagcctgcagcctgaagattttgcaacttattactgtctacaagactacaattacccgttcacttttggccaggggaccaagctggagatcaaacgaactgtggctgcaccatctgtcttcatcttcccgccatctgatgagcagttgaaatctggaactgcctctgttgtgtgcctgctgaataacttctatcccagagaggccaaagtacagtggaaggtggataacgccctccaatcgggtaactcccaggagagtgtcacagagcaggacagcaaggacagcacctacagcctcagcagcaccctgacgctgagcaaagcagactacgagaaacacaaagtctacgcctgcgaagtcacccatcagggcctgagctcgcccgtcacaaagagcttcaacaggggagagtgttag 214 AA PAT source 1..214 mol_type protein organism synthetic construct AIQMTQSPSSLSASVGDRVTITCRASQGIRYDLGWFQQKPGKAPKLLIHAASSLQSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCLQDYNYPFTFGQGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 372 DNA PAT source 1..372 mol_type other DNA organism synthetic construct gaggtgcagctattggagtctgggggagacttggtacagcctggggggtccctgagactctcctgtgcagcctctggattcacctttagcgactatgccatgatctgggtccgccagactccagggaagggactggaatgggtctcaggtatcagtggtggtggtggaagcacagactacgcagactccgtgaagggccggttcaccacctccagagacaatgtcaagaatgcgatgtatctgcaaatgaacagcctgagaaccgaggacacggccgtatattattgtgcgagagaggaccaactgccatcatatcacaattattacggtatggacgtctggggccaggggaccacggtcaccgtctcctca 124 AA PAT source 1..124 mol_type protein organism synthetic construct EVQLLESGGDLVQPGGSLRLSCAASGFTFSDYAMIWVRQTPGKGLEWVSGISGGGGSTDYADSVKGRFTTSRDNVKNAMYLQMNSLRTEDTAVYYCAREDQLPSYHNYYGMDVWGQGTTVTVSS 24 DNA PAT source 1..24 mol_type other DNA organism synthetic construct ggattcacctttagcgactatgcc 8 AA PAT source 1..8 mol_type protein organism synthetic construct GFTFSDYA 24 DNA PAT source 1..24 mol_type other DNA organism synthetic construct atcagtggtggtggtggaagcaca 8 AA PAT source 1..8 mol_type protein organism synthetic construct ISGGGGST 51 DNA PAT source 1..51 mol_type other DNA organism synthetic construct gcgagagaggaccaactgccatcatatcacaattattacggtatggacgtc 17 AA PAT source 1..17 mol_type protein organism synthetic construct AREDQLPSYHNYYGMDV 321 DNA PAT source 1..321 mol_type other DNA organism synthetic construct gacatccagatgacccagtctccatcctcagtgtctgcatctgtaggagacagagtcaccatcacttgtcgggcgagtcagggcatcaacaattatttagcctggtttcagcagaaaccagggaaagccccaaagtccctgatctatggcgcatccagtttgcaaagtggggtcccatcaaagttcagcggcagcagatctggcatagatttcactctcaccatcagcagcctgcagcctgaagattttgcaacttattactgccaacagtacaatagttatccgtacacttttggccaggggaccaagctggagatcaaa 107 AA PAT source 1..107 mol_type protein organism synthetic construct DIQMTQSPSSVSASVGDRVTITCRASQGINNYLAWFQQKPGKAPKSLIYGASSLQSGVPSKFSGSRSGIDFTLTISSLQPEDFATYYCQQYNSYPYTFGQGTKLEIK 18 DNA PAT source 1..18 mol_type other DNA organism synthetic construct cagggcatcaacaattat 6 AA PAT source 1..6 mol_type protein organism synthetic construct QGINNY 000 000 27 DNA PAT source 1..27 mol_type other DNA organism synthetic construct caacagtacaatagttatccgtacact 9 AA PAT source 1..9 mol_type protein organism synthetic construct QQYNSYPYT 1356 DNA PAT source 1..1356 mol_type other DNA organism synthetic construct gaggtgcagctattggagtctgggggagacttggtacagcctggggggtccctgagactctcctgtgcagcctctggattcacctttagcgactatgccatgatctgggtccgccagactccagggaagggactggaatgggtctcaggtatcagtggtggtggtggaagcacagactacgcagactccgtgaagggccggttcaccacctccagagacaatgtcaagaatgcgatgtatctgcaaatgaacagcctgagaaccgaggacacggccgtatattattgtgcgagagaggaccaactgccatcatatcacaattattacggtatggacgtctggggccaggggaccacggtcaccgtctcctcagcctccaccaagggcccatcggtcttccccctggcgccctgctccaggagcacctccgagagcacagccgccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcaggcgccctgaccagcggcgtgcacaccttcccggctgtcctacagtcctcaggactctactccctcagcagcgtggtgaccgtgccctccagcagcttgggcacgaagacctacacctgcaacgtagatcacaagcccagcaacaccaaggtggacaagagagttgagtccaaatatggtcccccatgcccaccctgcccagcacctgagttcctggggggaccatcagtcttcctgttccccccaaaacccaaggacactctcatgatctcccggacccctgaggtcacgtgcgtggtggtggacgtgagccaggaagaccccgaggtccagttcaactggtacgtggatggcgtggaggtgcataatgccaagacaaagccgcgggaggagcagttcaacagcacgtaccgtgtggtcagcgtcctcaccgtcctgcaccaggactggctgaacggcaaggagtacaagtgcaaggtctccaacaaaggcctcccgtcctccatcgagaaaaccatctccaaagccaaagggcagccccgagagccacaggtgtacaccctgcccccatcccaggaggagatgaccaagaaccaggtcagcctgacctgcctggtcaaaggcttctaccccagcgacatcgccgtggagtgggagagcaatgggcagccggagaacaactacaagaccacgcctcccgtgctggactccgacggctccttcttcctctacagcaggctcaccgtggacaagagcaggtggcaggaggggaatgtcttctcatgctccgtgatgcatgaggctctgcacaaccactacacacagaagtccctctccctgtctctgggtaaatga 451 AA PAT source 1..451 mol_type protein organism synthetic construct EVQLLESGGDLVQPGGSLRLSCAASGFTFSDYAMIWVRQTPGKGLEWVSGISGGGGSTDYADSVKGRFTTSRDNVKNAMYLQMNSLRTEDTAVYYCAREDQLPSYHNYYGMDVWGQGTTVTVSSASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTKTYTCNVDHKPSNTKVDKRVESKYGPPCPPCPAPEFLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSQEDPEVQFNWYVDGVEVHNAKTKPREEQFNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKGLPSSIEKTISKAKGQPREPQVYTLPPSQEEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSRLTVDKSRWQEGNVFSCSVMHEALHNHYTQKSLSLSLGK 645 DNA PAT source 1..645 mol_type other DNA organism synthetic construct gacatccagatgacccagtctccatcctcagtgtctgcatctgtaggagacagagtcaccatcacttgtcgggcgagtcagggcatcaacaattatttagcctggtttcagcagaaaccagggaaagccccaaagtccctgatctatggcgcatccagtttgcaaagtggggtcccatcaaagttcagcggcagcagatctggcatagatttcactctcaccatcagcagcctgcagcctgaagattttgcaacttattactgccaacagtacaatagttatccgtacacttttggccaggggaccaagctggagatcaaacgaactgtggctgcaccatctgtcttcatcttcccgccatctgatgagcagttgaaatctggaactgcctctgttgtgtgcctgctgaataacttctatcccagagaggccaaagtacagtggaaggtggataacgccctccaatcgggtaactcccaggagagtgtcacagagcaggacagcaaggacagcacctacagcctcagcagcaccctgacgctgagcaaagcagactacgagaaacacaaagtctacgcctgcgaagtcacccatcagggcctgagctcgcccgtcacaaagagcttcaacaggggagagtgttag 214 AA PAT source 1..214 mol_type protein organism synthetic construct DIQMTQSPSSVSASVGDRVTITCRASQGINNYLAWFQQKPGKAPKSLIYGASSLQSGVPSKFSGSRSGIDFTLTISSLQPEDFATYYCQQYNSYPYTFGQGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 469 AA PAT source 1..469 mol_type protein organism synthetic construct GNLTVAVVLPLANTSYPWSWARVGPAVELALAQVKARPDLLPGWTVRTVLGSSENALGVCSDTAAPLAAVDLKWEHNPAVFLGPGCVYAAAPVGRFTAHWRVPLLTAGAPALGFGVKDEYALTTRAGPSYAKLGDFVAALHRRLGWERQALMLYAYRPGDEEHCFFLVEGLFMRVRDRLNITVDHLEFAEDDLSHYTRLLRTMPRKGRVIYICSSPDAFRTLMLLALEAGLCGEDYVFFHLDIFGQSLQGGQGPAPRRPWERGDGQDVSARQAFQAAKIITYKDPDNPEYLEFLKQLKHLAYEQFNFTMEDGLVNTIPASFHDGLLLYIQAVTETLAHGGTVTDGENITQRMWNRSFQGVTGYLKIDSSGDRETDFSLWDMDPENGAFRVVLNYNGTSQELVAVSGRKLNWPLGYPPPDIPKCGFDNEDPACNQDHLSTLEEQKLISEEDLGGEQKLISEEDLHHHHHH 469 AA PAT source 1..469 mol_type protein organism synthetic construct GNLTVAVVLPLANTSYPWSWARVGPAVELALARVKARPDLLPGWTVRTVLGSSENALGVCSDTAAPLAAVDLKWEHNPAAFLGPGCVYAAAPVGRFTAHWRVPLLTAGAPALGFGVKDEYALTTRAGPSYAKLGDFVAALHRRLGWERQALMLYAYRPGDEEHCFFLVEGLFMRVRDRLNITVDHLEFAEDDLSHYTRLLRTMPRKGRVIYICSSPDAFRTLMLLALEAGLCGEDYVFFHLDIFGQSLQGGQGPAPRRPWERGDGQDVSARQAFQAAKIITYKEPDNPEYLEFLKQLKHLAREQFNFTMEDGLVNTIPASFHDGLLLYIQAVTETLAHGGTVTDGENITQRMWNRSFQGVTGYLKIDSSGDRETDFSLWDMDPETGAFRVVLNYNGTSQELVAVSGRKLNWPLGYPPPDIPKCGFDNEDPACNQDHLSTLEEQKLISEEDLGGEQKLISEEDLHHHHHH 469 AA PAT source 1..469 mol_type protein organism synthetic construct SDLTVAVVLPLTNTSYPWSWARVGPAVELALGRVKARPDLLPGWTVRMVLGSSENAAGVCSDTAAPLAAVDLKWEHSPAVFLGPGCVYSAAPVGRFTAHWRVPLLTAGAPALGIGVKDEYALTTRTGPSHVKLGDFVTALHRRLGWEHQALVLYADRLGDDRPCFFIVEGLYMRVRERLNITVNHQEFVEGDPDHYTKLLRTVQRKGRVIYICSSPDAFRNLMLLALDAGLTGEDYVFFHLDVFGQSLQGAQGPVPRKPWERDDGQDRRARQAFQAAKIITYKEPDNPEYLEFLKQLKLLADKKFNFTMEDGLKNIIPASFHDGLLLYVQAVTETLAQGGTVTDGENITQRMWNRSFQGVTGYLKIDRNGDRDTDFSLWDMDPETGAFRVVLNFNGTSQELMAVSEHRLYWPLGYPPPDIPKCGFDNEDPACNQDHFSTLEEQKLISEEDLGGEQKLISEEDLHHHHHH 469 AA PAT source 1..469 mol_type protein organism synthetic construct GNLTVAVVLPLANTSYPWSWARVGPAVELALAAVRAQPDLLPGWTVRTVLGSSENALGVCSDTAAPLAAVDLKWEHSPAVFLGPGCVYAAAPVGRFTAHWRVPLLTAGAPALGFGAKDEYALTTRAGPSHAKLGDLVAALHRRLGWERRALVLYAYRPGDDQPCFFVVEGLYVRVRERLNITVDHLEFAEGDLDQYALLLHTVRRQGRVIYICSSPDAFRTLMLLAMEAGLSGEDYVFFHLDLFGHSLQGAPGLAPHRPWERGDGQDVSAHQAFQAAKIITYKEPENPEYLEFLQQLKHLAHEQFNFTVEDGLVNTIPASFHDGLLLYVQAVTETLAHGGAVTDGEAITQRMRNRSFQGVTGYLKMDSNGDRETDFSLWDMHPETGTFRVVLNYNGTSQELVAVPGRKLSWPLGYPPPDIPKCGFDNEDPACSQDHFSTLEEQKLISEEDLGGEQKLISEEDLHHHHHH 469 AA PAT source 1..469 mol_type protein organism synthetic construct GNLTVAVVLPLANTSYPWSWARVGPAVELALAKVKARPDLLPGWTVRTVLGSSESALGVCSDTAAPLTAVDLKWEHNPAVFLGPGCVYAAAPVGRFTAHWRVPLLTAGAPALGFGAKDEYALTTRAGPSHAKLGDFVAALHRRLGWERQALVLYAYQPGDDQPCFFVVGGLYMRVRDRLNITVDHLEFAEGDRDHYTLLLRTVRRKGRVIYICSSPDTFRTLMLLALEAGLSGEDYVFFHLDLFGHSLQGAHGLVPRRPWEREDGQDVSAHQAFQAAKIITYKEPDNPEYLEFLRKLKHLAREQFNFTMEDGLVNTIPAAFHDGLLLYAQAVTETLAHGGTVTDGESITQRMWNRSFQGVTGYLKMDSNGDRETDFSLWDMDPETGAFRVVLNFNGTSQELVTVSGHTLNWPLGHPPPDVPRCGFDNEDPACNQDHFSTLEEQKLISEEDLGGEQKLISEEDLHHHHHH