OPP20239225KR KR 10-2023-0010403 2023-01-26 LepiDyne Co., Ltd. COMPOSITION FOR PREDICTING RISK OF DEVELOPING LIVER CANCER 17 514 DNA PAT source 1..514 mol_type genomic DNA organism Homo sapiens cgaggtaaagatcgtccagccttcataggccacctggttccgtccccctcccccagctactcgggcacgtgtcccgactcccgccagcaggccgtgggggtgatgtggccgccatgaacccaccaaggacaagtagggcctggttttagctgcaaatgcaacaagtctctccgctgagccgcagctgctaccctctgccttctgctcctccgccagggcacggccccccctgcgccccaaactgagcggcaaagtcagggcccgcggccggatgctcagagctaaaggccgcggaggacagatgtgcttcttcctccttcccgcgtctccccatacaagtactaccccgcacgtcccatcaggcttgcctgtgggccaggattcagggtcctgagccgaaacctaccaggagagagaaggctctggagacctctgtaacagtcgtgcggagaagacaaagtcagctgcgtgcgtctcctccggcgccggctctgcaaggagggaggagggggcg 611 DNA PAT source 1..611 mol_type genomic DNA organism Homo sapiens gggcgagggaggagcctgaggagactcgcccggctcaaccccgacgtccgcgccccggccgcctgttggccatggcgggcctgggcctgggctccgccgttcccgtgtggctggccgaggacgacctcggctgcatcatctgccaggggctgctggactggcccgccacgctgccctgcggccacagcttctgccgccactgcctggaggccctgtggggcgcccgcgacgcccgccgctgggcctgccccacttgccgccagggcgccgcgcagcagccgcacctgcggaagaacacgctactgcaggacctggccgacaagtaccgccgcgccgcacgcgagatacaggcgggctccgaccctgcccactgcccctgcccgggctccagttccctctccagcgcggccgcgaggccccggcgccgcccggaactgcagcgggtagggaggccgggcccgcagctcccctggctcccccgggctgcccgccgcctgaccctttcccatgtggctcgaacccctttcctcagccgttctacttttacgttccttttctcagtctaaaagtcgagttccgctcttcggaggcactttggaaagttcataaaa 1300 DNA PAT source 1..1300 mol_type genomic DNA organism Homo sapiens gggtgaggtcacttgctagaaccctgcgagggggcggtgccgaggcgtggaggtgatcggagtggacagagaggcggccccagaagttagtcggcgggatttgggcgcgagtgcttcccaagcgggcggggcaataggctgttccgggtgggacggaggacactggcggtctccgggacaaagacagcggttggggaagggatggatggccgggcctccaggcgtctccagactggggaaggggtagggggttaagggatcagagggcggcgtcctggccccgcaggcacgtgccgcgcccttcccccgggcccaggcccgcacccgcccgcctcccgtccgtgcaggcctcacctgggcctccagtcacgccgcagacaaggcgggctcgcgggggttcggggcgggctcgaggcccatggcccggcgactgcggcgggagcggtagagcgtccgggtgcgccctgtgcgggttgctgagagggcgcgggaggcggggtctccccggcgccccgcccccaccacctgggggagccctgccccgccccgccacctgggggagccccgcctccacggccgcgtcgggggcggtgtcgcccggaaccgcagcccccctgtttcctccccgcctcgcggcccctcagtcgcccctatttccggcgcgggacccccaccccggtacctgcacacctcatgcgcccgcagtttcgagcctgcggggctgagtcactcggcgacccgaaaattcccgccgtgaccccgcgctgcccgggcggagctccaggtggtcttgggtccgcgcccccgctccggacccccaaccctcccagccccaccccgctctcttcttcgtgtccaatcggccgccgagttacaagccactccctgatccgacttggctcccaccgcccggacccccgcccagcttcggctttgccagctcgcagtatcagcgagccgcggcctcctgtgcgaggcccacctctgcggccccagctgatcatcgggcgcacgctagggttttgcaatcccgcccccgtacccctcaccctgggacagcgctgccccctgcaaagcccggccctgccctgccctgccctgtggcttcctccctcggcctccctgcggcggccccgggctcccacggtccggagcacacagccccattgtcccggttatcggtactttgttatactgtatttgattatgcaggaccggatcggggacgcagagctccgggagggccgggctggcgtgactcagccgggtgctgcgacccagctccaactgcctttacgta 514 DNA PAT misc_feature 1..514 note Bisulfite converted Marker 1 source 1..514 mol_type other DNA organism synthetic construct cgaggtaaagatcgtttagtttttataggttatttggtttcgttttttttttttagttattcgggtacgtgtttcgattttcgttagtaggtcgtgggggtgatgtggtcgttatgaatttattaaggataagtagggtttggttttagttgtaaatgtaataagttttttcgttgagtcgtagttgttattttttgttttttgttttttcgttagggtacggttttttttgcgttttaaattgagcggtaaagttagggttcgcggtcggatgtttagagttaaaggtcgcggaggatagatgtgtttttttttttttttcgcgtttttttatataagtattatttcgtacgttttattaggtttgtttgtgggttaggatttagggttttgagtcgaaatttattaggagagagaaggttttggagatttttgtaatagtcgtgcggagaagataaagttagttgcgtgcgtttttttcggcgtcggttttgtaaggagggaggagggggcg 611 DNA PAT misc_feature 1..611 note Bisulfite converted Marker 2 source 1..611 mol_type other DNA organism synthetic construct gggcgagggaggagtttgaggagattcgttcggtttaatttcgacgttcgcgtttcggtcgtttgttggttatggcgggtttgggtttgggtttcgtcgttttcgtgtggttggtcgaggacgatttcggttgtattatttgttaggggttgttggattggttcgttacgttgttttgcggttatagtttttgtcgttattgtttggaggttttgtggggcgttcgcgacgttcgtcgttgggtttgttttatttgtcgttagggcgtcgcgtagtagtcgtatttgcggaagaatacgttattgtaggatttggtcgataagtatcgtcgcgtcgtacgcgagatataggcgggtttcgattttgtttattgtttttgttcgggttttagttttttttttagcgcggtcgcgaggtttcggcgtcgttcggaattgtagcgggtagggaggtcgggttcgtagtttttttggttttttcgggttgttcgtcgtttgatttttttttatgtggttcgaatttttttttttagtcgttttatttttacgtttttttttttagtttaaaagtcgagtttcgtttttcggaggtattttggaaagtttataaaa 1300 DNA PAT misc_feature 1..1300 note Bisulfite converted Marker 3 source 1..1300 mol_type other DNA organism synthetic construct gggtgaggttatttgttagaattttgcgagggggcggtgtcgaggcgtggaggtgatcggagtggatagagaggcggttttagaagttagtcggcgggatttgggcgcgagtgttttttaagcgggcggggtaataggttgtttcgggtgggacggaggatattggcggttttcgggataaagatagcggttggggaagggatggatggtcgggtttttaggcgtttttagattggggaaggggtagggggttaagggattagagggcggcgttttggtttcgtaggtacgtgtcgcgtttttttttcgggtttaggttcgtattcgttcgtttttcgttcgtgtaggttttatttgggtttttagttacgtcgtagataaggcgggttcgcgggggttcggggcgggttcgaggtttatggttcggcgattgcggcgggagcggtagagcgttcgggtgcgttttgtgcgggttgttgagagggcgcgggaggcggggttttttcggcgtttcgtttttattatttgggggagttttgtttcgtttcgttatttgggggagtttcgtttttacggtcgcgtcgggggcggtgtcgttcggaatcgtagtttttttgtttttttttcgtttcgcggttttttagtcgtttttattttcggcgcgggatttttatttcggtatttgtatattttatgcgttcgtagtttcgagtttgcggggttgagttattcggcgattcgaaaattttcgtcgtgatttcgcgttgttcgggcggagttttaggtggttttgggttcgcgttttcgtttcggatttttaatttttttagttttatttcgttttttttttcgtgtttaatcggtcgtcgagttataagttattttttgattcgatttggtttttatcgttcggattttcgtttagtttcggttttgttagttcgtagtattagcgagtcgcggttttttgtgcgaggtttatttttgcggttttagttgattatcgggcgtacgttagggttttgtaatttcgttttcgtattttttattttgggatagcgttgttttttgtaaagttcggttttgttttgttttgttttgtggttttttttttcggtttttttgcggcggtttcgggtttttacggttcggagtatatagttttattgtttcggttatcggtattttgttatattgtatttgattatgtaggatcggatcggggacgtagagtttcgggagggtcgggttggcgtgatttagtcgggtgttgcgatttagttttaattgtttttacgta 20 DNA PAT misc_feature 1..20 note Methylated Forward Primer for Marker 1 source 1..20 mol_type other DNA organism synthetic construct aaccgacgccgaaaaaaacg 26 DNA PAT misc_feature 1..26 note Methylated Reverse Primer for Marker 1 source 1..26 mol_type other DNA organism synthetic construct gaaggttttggagatttttgtaatag 26 DNA PAT misc_feature 1..26 note Unmethylated Forward Primer for Marker 1 source 1..26 mol_type other DNA organism synthetic construct ttacaaaaccaacaccaaaaaaaaca 28 DNA PAT misc_feature 1..28 note Methylated Forward Primer for marker 1 source 1..28 mol_type other DNA organism synthetic construct gagaaggttttggagatttttgtaatag 21 DNA PAT misc_feature 1..21 note Methylated Reverse Primer for marker 1 source 1..21 mol_type other DNA organism synthetic construct ctccttacaaaaccgacgccg 20 DNA PAT misc_feature 1..20 note Unmethylated Reverse Primer for marker 1 source 1..20 mol_type other DNA organism synthetic construct tccttacaaaaccaacacca 25 DNA PAT misc_feature 1..25 note Methylated Forward Primer for Marker 2 source 1..25 mol_type other DNA organism synthetic construct ttatggcgggtttgggtttgggttt 24 DNA PAT misc_feature 1..24 note Methylated Reverse Primer for Marker 2 source 1..24 mol_type other DNA organism synthetic construct caacccctaacaaataatacaacc 22 DNA PAT misc_feature 1..22 note Methylated Forward Primer for Marker 3 source 1..22 mol_type other DNA organism synthetic construct ggattagggagtggtttgtaat 18 DNA PAT misc_feature 1..18 note Methylated Reverse Primer for Marker 3 source 1..18 mol_type other DNA organism synthetic construct cccgctctcttcttcgta 20 DNA PAT misc_feature 1..20 note Unmethylated Reverse Primer for Marker 3 source 1..20 mol_type other DNA organism synthetic construct accccactctcttcttcata