WO 2022-11-30 SAP-882-PCT JP 2021195792 2021-12-01 株式会社Ｅｐｓｉｌｏｎ　Ｍｏｌｅｃｕｌａｒ　Ｅｎｇｉｎｅｅｒｉｎｇ Epsilon Molecular Engineering, Inc. ランダム領域搭載用フレームワーク配列を有するペプチド及びそのペプチドで構成されるペプチドライブラリ Peptide having framework sequences for implementing random sequences and peptide library comprising thereof 37 25 AA PAT source 1..25 mol_type protein organism synthetic construct EVQLVESGGGLVQPGGSLRLSCAAS 14 AA PAT source 1..14 mol_type protein organism synthetic construct VARIANT 2 note X can be any amino acid VARIANT 10 note X can be any amino acid WXRQAPGKGXEXVA 14 AA PAT source 1..14 mol_type protein organism synthetic construct WYRQAPGKGLEWVA 14 AA PAT source 1..14 mol_type protein organism synthetic construct WVRQAPGKGLEWVA 14 AA PAT source 1..14 mol_type protein organism synthetic construct WFRQAPGKGREFVA 14 AA PAT source 1..14 mol_type protein organism synthetic construct WFRQAPGKGREGVA 32 AA PAT source 1..32 mol_type protein organism synthetic construct VARIANT 13 note X can be any amino acid VARIANT 31 note X can be any amino acid VARIANT 32 note X can be any amino acid RFTISRDNAKNTXYLQMNSLRAEDTAVYYCXX 32 AA PAT source 1..32 mol_type protein organism synthetic construct RFTISRDNAKNTLYLQMNSLRAEDTAVYYCNA 32 AA PAT source 1..32 mol_type protein organism synthetic construct RFTISRDNAKNTLYLQMNSLRAEDTAVYYCNV 32 AA PAT source 1..32 mol_type protein organism synthetic construct RFTISRDNAKNTLYLQMNSLRAEDTAVYYCNR 32 AA PAT source 1..32 mol_type protein organism synthetic construct RFTISRDNAKNTLYLQMNSLRAEDTAVYYCNL 9 AA PAT source 1..9 mol_type protein organism synthetic construct FRUPRIGHT 32 AA PAT source 1..32 mol_type protein organism synthetic construct RFTISRDNAKNTVYLQMNSLRAEDTAVYYCNV 32 AA PAT source 1..32 mol_type protein organism synthetic construct RFTISRDNAKNTVYLQMNSLRAEDTAVYYCNR 32 AA PAT source 1..32 mol_type protein organism synthetic construct RFTISRDNAKNTVYLQMNSLRAEDTAVYYCNL 32 AA PAT source 1..32 mol_type protein organism synthetic construct RFTISRDNAKNTLYLQMNSLRAEDTAVYYCAV 32 AA PAT source 1..32 mol_type protein organism synthetic construct RFTISRDNAKNTLYLQMNSLRAEDTAVYYCAR 32 AA PAT source 1..32 mol_type protein organism synthetic construct RFTISRDNAKNTLYLQMNSLRAEDTAVYYCAL 32 AA PAT source 1..32 mol_type protein organism synthetic construct RFTISRDNAKNTVYLQMNSLRAEDTAVYYCAV 32 AA PAT source 1..32 mol_type protein organism synthetic construct RFTISRDNAKNTVYLQMNSLRAEDTAVYYCAR 32 AA PAT source 1..32 mol_type protein organism synthetic construct RFTISRDNAKNTVYLQMNSLRAEDTAVYYCAL 32 AA PAT source 1..32 mol_type protein organism synthetic construct RFTISRDNAKNTLYLQMNSLRAEDTAVYYCKA 32 AA PAT source 1..32 mol_type protein organism synthetic construct RFTISRDNAKNTLYLQMNSLRAEDTAVYYCKV 32 AA PAT source 1..32 mol_type protein organism synthetic construct RFTISRDNAKNTLYLQMNSLRAEDTAVYYCKR 32 AA PAT source 1..32 mol_type protein organism synthetic construct RFTISRDNAKNTLYLQMNSLRAEDTAVYYCKL 32 AA PAT source 1..32 mol_type protein organism synthetic construct RFTISRDNAKNTVYLQMNSLRAEDTAVYYCKA 32 AA PAT source 1..32 mol_type protein organism synthetic construct RFTISRDNAKNTVYLQMNSLRAEDTAVYYCKV 32 AA PAT source 1..32 mol_type protein organism synthetic construct RFTISRDNAKNTVYLQMNSLRAEDTAVYYCKR 32 AA PAT source 1..32 mol_type protein organism synthetic construct RFTISRDNAKNTVYLQMNSLRAEDTAVYYCKL 32 AA PAT source 1..32 mol_type protein organism synthetic construct RFTISRDNAKNTLYLQMNSLRAEDTAVYYCAA 32 AA PAT source 1..32 mol_type protein organism synthetic construct RFTISRDNAKNTVYLQMNSLRAEDTAVYYCAA 11 AA PAT source 1..11 mol_type protein organism synthetic construct WGQGTLVTVSS 23 DNA PAT source 1..23 mol_type other DNA organism synthetic construct misc_feature 3 note n is guanosine misc_feature 12 note n is 3-cyanovinylcarbazole aanaatttccangccgccccccg 25 AA PAT source 1..25 mol_type protein organism synthetic construct EVQLLESGGGLVQPGGSLRLSCAAS 14 AA PAT source 1..14 mol_type protein organism synthetic construct WVRQAPGKGLEWVS 32 AA PAT source 1..32 mol_type protein organism synthetic construct RFTISRDNSKNTLYLQMNSLRAEDTAVYYCAK 11 AA PAT source 1..11 mol_type protein organism synthetic construct WGQGTLVTVSS