CFP034754 US 63/540,954 2023-09-28 PELL BIO-MED TECHNOLOGY CO., LTD. NUCLEIC ACID MOLECULE COMPRISING INTRACELLULAR SIGNALING DOMAIN AND NKP30 TRANSMEMBRANE DOMAIN AND CHIMERIC ANTIGEN RECEPTOR COMPRISING THE SAME 99 242 AA PAT source 1..242 mol_type protein organism synthetic construct SITE 1..242 note anti BCMA VHH1-GGGGS -VHH2 QVKLEESGGGLVQAGRSLRLSCAASEHTFSSHVMGWFRQAPGKERESVAVIGWRDISTSYADSVKGRFTISRDNAKKTLYLQMNSLKPEDTAVYYCAARRIDAADFDSWGQGTQVTVSSGGGGSEVQLVESGGGLVQAGGSLRLSCAASGRTFTMGWFRQAPGKEREFVAAISLSPTLAYYAESVKGRFTISRDNAKNTVVLQMNSLKPEDTALYYCAADRKSVMSIRPDYWGQGTQVTVSS 119 AA PAT source 1..119 mol_type protein organism synthetic construct SITE 1..119 note anti BCMA VHH1 QVKLEESGGGLVQAGRSLRLSCAASEHTFSSHVMGWFRQAPGKERESVAVIGWRDISTSYADSVKGRFTISRDNAKKTLYLQMNSLKPEDTAVYYCAARRIDAADFDSWGQGTQVTVSS 118 AA PAT source 1..118 mol_type protein organism synthetic construct SITE 1..118 note anti BCMA VHH2 EVQLVESGGGLVQAGGSLRLSCAASGRTFTMGWFRQAPGKEREFVAAISLSPTLAYYAESVKGRFTISRDNAKNTVVLQMNSLKPEDTALYYCAADRKSVMSIRPDYWGQGTQVTVSS 9 AA PAT source 1..9 mol_type protein organism synthetic construct SITE 1..9 note anti BCMA VHH1 CDRH1 HTFSSHVMG 11 AA PAT source 1..11 mol_type protein organism synthetic construct SITE 1..11 note anti BCMA VHH1 CDRH2 GWRDISTSYAD 12 AA PAT source 1..12 mol_type protein organism synthetic construct SITE 1..12 note anti BCMA VHH1 CDRH3 AARRIDAADFDS 6 AA PAT source 1..6 mol_type protein organism synthetic construct SITE 1..6 note anti BCMA VHH2 CDRH1 RTFTMG 11 AA PAT source 1..11 mol_type protein organism synthetic construct SITE 1..11 note anti BCMA VHH2 CDRH2 SLSPTLAYYAE 14 AA PAT source 1..14 mol_type protein organism synthetic construct SITE 1..14 note anti BCMA VHH2 CDRH3 AADRKSVMSIRPDY 10 AA PAT source 1..10 mol_type protein organism synthetic construct SITE 1..10 note anti CD19 antibody(FMC63) CDRH1 GVSLPDYGVS 16 AA PAT source 1..16 mol_type protein organism synthetic construct SITE 1..16 note anti CD19 antibody(FMC63) CDRH2 VIWGSETTYYNSALKS 12 AA PAT source 1..12 mol_type protein organism synthetic construct SITE 1..12 note anti CD19 antibody(FMC63) CDRH3 HYYYGGSYAMDY 11 AA PAT source 1..11 mol_type protein organism synthetic construct SITE 1..11 note anti CD19 antibody(FMC63) CDRL1 RASQDISKYLN 7 AA PAT source 1..7 mol_type protein organism synthetic construct SITE 1..7 note anti CD19 antibody(FMC63) CDRL2 SRLHSGV 9 AA PAT source 1..9 mol_type protein organism synthetic construct SITE 1..9 note anti CD19 antibody(FMC63) CDRL3 QQGNTLPYT 242 AA PAT source 1..242 mol_type protein organism synthetic construct SITE 1..242 note FMC63 scfv DIQMTQTTSSLSASLGDRVTISCRASQDISKYLNWYQQKPDGTVKLLIYHTSRLHSGVPSRFSGSGSGTDYSLTISNLEQEDIATYFCQQGNTLPYTFGGGTKLEITGGGGSGGGGSGGGGSEVKLQESGPGLVAPSQSLSVTCTVSGVSLPDYGVSWIRQPPRKGLEWLGVIWGSETTYYNSALKSRLTIIKDNSKSQVFLKMNSLQTDDTAIYYCAKHYYYGGSYAMDYWGQGTSVTVSS 5 AA PAT source 1..5 mol_type protein organism synthetic construct SITE 1..5 note anti mesothelin antibody(SS1) CDRH1 GYTMN 15 AA PAT source 1..15 mol_type protein organism synthetic construct SITE 1..15 note anti mesothelin antibody(SS1) CDRH2 LITPYNGASSYNQKF 10 AA PAT source 1..10 mol_type protein organism synthetic construct SITE 1..10 note anti mesothelin antibody(SS1) CDRH3 GGYDGRGFDY 10 AA PAT source 1..10 mol_type protein organism synthetic construct SITE 1..10 note anti mesothelin antibody(SS1) CDRL1 SASSSVSYMH 7 AA PAT source 1..7 mol_type protein organism synthetic construct SITE 1..7 note anti mesothelin antibody(SS1) CDRL2 DTSKLAS 9 AA PAT source 1..9 mol_type protein organism synthetic construct SITE 1..9 note anti mesothelin antibody(SS1) CDRL3 QQWSKHPLT 240 AA PAT source 1..240 mol_type protein organism synthetic construct SITE 1..240 note SS1 scfv QVQLQQSGPELEKPGASVKLSCKASGYSFTGYTMNWVKQSHGKSLEWIGLITPYNGASSYNQKFRGKATLTVDKSSSTAYMDLLSLTSEDSAVYFCARGGYDGRGFDYWGQGTTVTVSSGVGGSGGGGSGGGGSDIELTQSPAIMSASPGEKVTMTCSASSSVSYMHWYQQKSGTSPKRWIYDTSKLASGVPGRFSGSGSGNSYSLTISSVEAEDDATYYCQQWSKHPLTFGAGTKLEIK 10 AA PAT source 1..10 mol_type protein organism synthetic construct SITE 1..10 note anti BCMA antibody(J6M0) CDRH1 GGTFSNYWMH 17 AA PAT source 1..17 mol_type protein organism synthetic construct SITE 1..17 note anti BCMA antibody(J6M0) CDRH2 ATYRGHSDTYYNQKFKG 12 AA PAT source 1..12 mol_type protein organism synthetic construct SITE 1..12 note anti BCMA antibody(J6M0) CDRH3 GAIYDGYDVLDN 11 AA PAT source 1..11 mol_type protein organism synthetic construct SITE 1..11 note anti BCMA antibody(J6M0) CDRL1 SASQDISNYLN 7 AA PAT source 1..7 mol_type protein organism synthetic construct SITE 1..7 note anti BCMA antibody(J6M0) CDRL2 YTSNLHS 9 AA PAT source 1..9 mol_type protein organism synthetic construct SITE 1..9 note anti BCMA antibody(J6M0) CDRL3 QQYRKLPWT 244 AA PAT source 1..244 mol_type protein organism synthetic construct SITE 1..244 note J6M0 scfv QVQLVQSGAEVKKPGSSVKVSCKASGGTFSNYWMHWVRQAPGQGLEWMGATYRGHSDTYYNQKFKGRVTITADKSTSTAYMELSSLRSEDTAVYYCARGAIYDGYDVLDNWGQGTLVTVSSGGGGSGGGGSGGGGSDIQMTQSPSSLSASVGDRVTITCSASQDISNYLNWYQQKPGKAPKLLIYYTSNLHSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQYRKLPWTFGQGTKLEIKR 10 AA PAT source 1..10 mol_type protein organism synthetic construct SITE 1..10 note anti BCMA antibody(BB2121) CDRH1 GYTFTDYSIN 17 AA PAT source 1..17 mol_type protein organism synthetic construct SITE 1..17 note anti BCMA antibody(BB2121) CDRH2 WINTETREPAYAYDFRG 8 AA PAT source 1..8 mol_type protein organism synthetic construct SITE 1..8 note anti BCMA antibody(BB2121) CDRH3 DYSYAMDY 15 AA PAT source 1..15 mol_type protein organism synthetic construct SITE 1..15 note anti BCMA antibody(BB2121) CDRL1 RASESVTILGSHLIH 7 AA PAT source 1..7 mol_type protein organism synthetic construct SITE 1..7 note anti BCMA antibody(BB2121) CDRL2 LASNVQT 8 AA PAT source 1..8 mol_type protein organism synthetic construct SITE 1..8 note anti BCMA antibody(BB2121) CDRL3 QSRTIPRT 246 AA PAT source 1..246 mol_type protein organism synthetic construct SITE 1..246 note BB2121 scfv DIVLTQSPPSLAMSLGKRATISCRASESVTILGSHLIHWYQQKPGQPPTLLIQLASNVQTGVPARFSGSGSRTDFTLTIDPVEEDDVAVYYCLQSRTIPRTFGGGTKLEIKGSTSGSGKPGSGEGSTKGQIQLVQSGPELKKPGETVKISCKASGYTFTDYSINWVKRAPGKGLKWMGWINTETREPAYAYDFRGRFAFSLETSASTAYLQINNLKYEDTATYFCALDYSYAMDYWGQGTSVTVSS 8 AA PAT source 1..8 mol_type protein organism synthetic construct SITE 1..8 note anti CD22 antibody(m971) CDRH1 SSNSAAWN 18 AA PAT source 1..18 mol_type protein organism synthetic construct SITE 1..18 note anti CD22 antibody(m971) CDRH2 RTYYRSKWYNDYAVSVKS 12 AA PAT source 1..12 mol_type protein organism synthetic construct SITE 1..12 note anti CD22 antibody(m971) CDRH3 EVTGDLEDAFDI 10 AA PAT source 1..10 mol_type protein organism synthetic construct SITE 1..10 note anti CD22 antibody(m971) CDRL1 RASQTIWSYL 7 AA PAT source 1..7 mol_type protein organism synthetic construct SITE 1..7 note anti CD22 antibody(m971) CDRL2 AASSLQS 9 AA PAT source 1..9 mol_type protein organism synthetic construct SITE 1..9 note anti CD22 antibody(m971) CDRL3 QQSYSIPQT 246 AA PAT source 1..246 mol_type protein organism synthetic construct SITE 1..246 note m971 scfv QVQLQQSGPGLVKPSQTLSLTCAISGDSVSSNSAAWNWIRQSPSRGLEWLGRTYYRSKWYNDYAVSVKSRITINPDTSKNQFSLQLNSVTPEDTAVYYCAREVTGDLEDAFDIWGQGTMVTVSSGGGGSGGGGSGGGGSDIQMTQSPSSLSASVGDRVTITCRASQTIWSYLNWYQQRPGKAPNLLIYAASSLQSGVPSRFSGRGSGTDFTLTISSLQAEDFATYYCQQSYSIPQTFGQGTKLEIK 10 AA PAT source 1..10 mol_type protein organism synthetic construct SITE 1..10 note anti CD22 antibody(LL2) CDRH1 GYTFTSYWLH 17 AA PAT source 1..17 mol_type protein organism synthetic construct SITE 1..17 note anti CD22 antibody(LL2) CDRH2 YINPRNDYTEYNQNFKD 7 AA PAT source 1..7 mol_type protein organism synthetic construct SITE 1..7 note anti CD22 antibody(LL2) CDRH3 RDITIFY 16 AA PAT source 1..16 mol_type protein organism synthetic construct SITE 1..16 note anti CD22 antibody(LL2) CDRL1 KSSQSVLYSANHKNYL 7 AA PAT source 1..7 mol_type protein organism synthetic construct SITE 1..7 note anti CD22 antibody(LL2) CDRL2 WASTRES 8 AA PAT source 1..8 mol_type protein organism synthetic construct SITE 1..8 note anti CD22 antibody(LL2) CDRL3 HQTLSSWT 244 AA PAT source 1..244 mol_type protein organism synthetic construct SITE 1..244 note LL2 scfv QVQLVQSGAEVKKPGSSVKVSCKASGYTFTSYWLHWVRQAPGQGLEWIGYINPRNDYTEYNQNFKDKATITADESTNTAYMELSSLRSEDTAFYFCARRDITTFYWGQGTTVTVSSGGGGSGGGGSGGGGSDIQLTQSPSSLSASVGDRVTMSCKSSQSVLYSANHKNYLAWYQQKPGKAPKLLIYWASTRESGVPSRFSGSGSGTDFTFTISSLQPEDIATYYCHQYLSSWTFGGGTKLEIKR 10 AA PAT source 1..10 mol_type protein organism synthetic construct SITE 1..10 note anti CD22 antibody(G5/44) CDRH1 GYRFTNYWIH 17 AA PAT source 1..17 mol_type protein organism synthetic construct SITE 1..17 note anti CD22 antibody(G5/44) CDRH2 GINPGNNYATYRRKFQG 12 AA PAT source 1..12 mol_type protein organism synthetic construct SITE 1..12 note anti CD22 antibody(G5/44) CDRH3 EGYGNYGAWFAY 15 AA PAT source 1..15 mol_type protein organism synthetic construct SITE 1..15 note anti CD22 antibody(G5/44) CDRL1 RSSQSLANSYGNTFL 7 AA PAT source 1..7 mol_type protein organism synthetic construct SITE 1..7 note anti CD22 antibody(G5/44) CDRL2 GISNRFS 9 AA PAT source 1..9 mol_type protein organism synthetic construct SITE 1..9 note anti CD22 antibody(G5/44) CDRL3 LQGTHQPYT 249 AA PAT source 1..249 mol_type protein organism synthetic construct SITE 1..249 note G5/44 scfv EVQLVQSGAEVKKPGASVKVSCKASGYRFTNYWIHWVRQAPGQGLEWIGGINPGNNYATYRRKFQGRVTMTADTSTSTVYMELSSLRSEDTAVYYCTREGYGNYGAWFAYWGQGTLVTVSSGGGGSGGGGSGGGGSDVQVTQSPSSLSASVGDRVTITCRSSQSLANSYGNTFLSWYLHKPGKAPQLLIYGISNRFSGVPDRFSGSGSGTDFTLTISSLQPEDFATYYCLQGTHQPYTFGQGTKVEIKR 10 AA PAT source 1..10 mol_type protein organism synthetic construct SITE 1..10 note anti CD22 antibody(RFB4) CDRH1 GFTFSIYDMS 17 AA PAT source 1..17 mol_type protein organism synthetic construct SITE 1..17 note anti CD22 antibody(RFB4) CDRH2 YISSGGGTTYYPDTVKG 14 AA PAT source 1..14 mol_type protein organism synthetic construct SITE 1..14 note anti CD22 antibody(RFB4) CDRH3 HSGYGSSYGVLFAY 10 AA PAT source 1..10 mol_type protein organism synthetic construct SITE 1..10 note anti CD22 antibody(RFB4) CDRL1 RASQTISNYL 7 AA PAT source 1..7 mol_type protein organism synthetic construct SITE 1..7 note anti CD22 antibody(RFB4) CDRL2 YTSILHS 9 AA PAT source 1..9 mol_type protein organism synthetic construct SITE 1..9 note anti CD22 antibody(RFB4) CDRL3 QQGNTLPWT 244 AA PAT source 1..244 mol_type protein organism synthetic construct SITE 1..244 note RFB4 scfv QLVQSGAEVKKPGSSVKVSCKASGFTFSIYDMSWVRQAPGQGLEWVAYISSGGGTTYYPDTVKGRFTITADESTNTAYMELSSLRSEDTAFYFCARHSGYGSSYGVLFAYWGQGTLVTVSSGGGGSGGGGSGGGGSDIQLTQSPSSLSASVGDRVTISCRASQDISNYLNWYQQKPGKAPKLLIYYTSILHSGVPSRFSGSGSGTDYTFTISSLQPEDIATYYCQQGNTLPWTFGGGTKVQIKR 45 DNA PAT source 1..45 mol_type other DNA organism synthetic construct misc_feature 1..45 note (G4S)3 hinge ggcggcggaggctctggcggcggcggcagcggcggcggaggctcc 207 DNA PAT source 1..207 mol_type other DNA organism synthetic construct misc_feature 1..207 note CD8 hinge accactaccccagcaccgaggccacccaccccggctcctaccatcgcctcccagcctctgtccctgcgtccggaggcatgtagacccgcagctggtggggccgtgcatacccggggtcttgacttcgcctgcgatatctacatttgggcccctctggctggtacttgcggggtcctgctgctttcactcgtgatcactctttactgt 117 DNA PAT source 1..117 mol_type other DNA organism synthetic construct misc_feature 1..117 note CD28 hinge attgaagttatgtatcctcctccttacctagacaatgagaagagcaatggaaccattatccatgtgaaagggaaacacctttgtccaagtcccctatttcccggaccttctaagccc 36 DNA PAT source 1..36 mol_type other DNA organism synthetic construct misc_feature 1..36 note IgG4 hinge gagtccaaatatggtcccccatgcccatcatgccca 30 DNA PAT source 1..30 mol_type other DNA organism synthetic construct misc_feature 1..30 note EAAAKGGGGS hinge gaagcggcggcgaaaggaggaggaggaagc 45 DNA PAT source 1..45 mol_type other DNA organism synthetic construct misc_feature 1..45 note (EAAAK)3 hinge gaagcagccgctaaagaggcagctgctaaggaagccgcagctaaa 54 DNA PAT source 1..54 mol_type other DNA organism synthetic construct misc_feature 1..54 note GST hinge ggaagcacgtccggctcagggaagccgggctccggcgagggaagcacgaagggg 60 DNA PAT source 1..60 mol_type other DNA organism synthetic construct misc_feature 1..60 note EAAAK-GS hinge gaagcagccgctaaaggcggaggcggttctggaggcggtggctccgcggccgcagctaag 192 DNA PAT source 1..192 mol_type other DNA organism synthetic construct misc_feature 1..192 note IgD hinge aggtggcccgaaagtcccaaggcccaggcatctagtgttcctactgcacagccccaggcagaaggcagcctagccaaagctactactgcacctgccactacgcgcaatactggccgtggcggggaggagaagaaaaaggagaaagagaaagaagaacaggaagagagggagaccaagacccctgaatgtcca 357 DNA PAT source 1..357 mol_type other DNA organism synthetic construct misc_feature 1..357 note IgG4-CH3 hinge gagtccaaatatggtcccccatgcccatcatgcccagggcagccccgagagccacaggtgtacaccctgcccccatcccaggaggagatgaccaagaaccaggtcagcctgacctgcctggtcaaaggcttctaccccagcgacatcgccgtggagtgggagagcaatgggcagccggagaacaactacaagaccacgcctcccgtgctggactccgacggctccttcttcctctacagcaggctaaccgtggacaagagcaggtggcaggaggggaatgtcttctcatgctccgtgatgcatgaggctctgcacaaccactacacacagaagagcctctccctgtctctgggtaaa 36 DNA PAT source 1..36 mol_type other DNA organism synthetic construct misc_feature 1..36 note (AP)6 hinge gcacctgcccctgcaccagctccagctcccgcccca 258 DNA PAT source 1..258 mol_type other DNA organism synthetic construct misc_feature 1..258 note DNA sequence of Fc epsilon R1 gamma atgattccagcagtggtcttgctcttactccttttggttgaacaagcagcggccctgggagagcctcagctctgctatatcctggatgccatcctgtttctgtatggaattgtcctcaccctcctctactgtcgactgaagatccaagtgcgaaaggcagctataaccagctatgagaaatcagatggtgtttacacgggcctgagcaccaggaaccaggagacttacgagactctgaagcatgagaaaccaccacag 156 DNA PAT source 1..156 mol_type other DNA organism synthetic construct misc_feature 1..156 note DNA sequence of DAP12 intracellular signaling domain tacttcctgggccggctggtccctcgggggcgaggggctgcggaggcagcgacccggaaacagcgtatcactgagaccgagtcgccttatcaggagctccagggtcagaggtcggatgtctacagcgacctcaacacacagaggccgtattacaaa 612 DNA PAT source 1..612 mol_type other DNA organism synthetic construct misc_feature 1..612 note NKp30 (DNA sequence) atggcctggatgctgctgctgatcctgatcatggtgcaccctggctcttgcgcactgtgggtgagccagccaccagagatccgcacactggagggcagctccgccttcctgccatgttcctttaacgcatctcagggccggctggcaatcggctccgtgacctggtttagagacgaggtggtgcccggcaaggaggtgaggaatggcacacccgagttcaggggccgcctggcacctctggcctctagccggtttctgcacgatcaccaggccgagctgcacatccgggacgtgagaggccacgatgcctctatctacgtgtgccgggtggaggtgctgggcctgggagtgggcaccggcaacggcacacggctggtggtggagaaggagcaccctcagctgggagcaggcaccgtgctgctgctgagggccggcttctatgccgtgagctttctgtccgtggccgtgggctccaccgtgtactatcagggcaagtgcctgacatggaaaggcccccggagacagctgccagccgtggtgccagcaccactgcctccaccctgtggctcctctgcccacctgctgcctccagtgcccggcggctgagaattc 63 DNA PAT source 1..63 mol_type other DNA organism synthetic construct misc_feature 1..63 note T2A (DNA sequence) ggctctggagagggaagaggcagcctgctgacctgcggcgacgtggaggagaatcctggccca 1101 DNA PAT source 1..1101 mol_type other DNA organism synthetic construct misc_feature 1..1101 note the nucleic acid molecule of example 1-1 ttcgaagccaccatgatcccagccgtggtgctgctgctgctgctgctggtggagcaggccgccgccctgggagagccccagctgtgctacatcctggacgccatcctgttcctgtacggcatcgtgctgaccctgctgtattgtaggctgaagatccaggtgcgcaaggccgccatcacatcttacgagaagagcgatggcgtgtataccggcctgagcacaagaaaccaggagacatacgagacactgaagcacgagaagccacctcagtacttcctgggccggctggtgccaaggggaagaggagcagcagaggcagccaccaggaagcagcgcatcaccgagacagagtctccataccaggagctgcagggacagcggagcgacgtgtattccgatctgaacacacagaggccttactataagggcagcggagagggaaggggctccctgctgacctgcggcgacgtggaggagaatcccggccctatggcctggatgctgctgctgatcctgatcatggtgcaccctggctcttgcgcactgtgggtgagccagccaccagagatccgcacactggagggcagctccgccttcctgccatgttcctttaacgcatctcagggccggctggcaatcggctccgtgacctggtttagagacgaggtggtgcccggcaaggaggtgaggaatggcacacccgagttcaggggccgcctggcacctctggcctctagccggtttctgcacgatcaccaggccgagctgcacatccgggacgtgagaggccacgatgcctctatctacgtgtgccgggtggaggtgctgggcctgggagtgggcaccggcaacggcacacggctggtggtggagaaggagcaccctcagctgggagcaggcaccgtgctgctgctgagggccggcttctatgccgtgagctttctgtccgtggccgtgggctccaccgtgtactatcagggcaagtgcctgacatggaaaggcccccggagacagctgccagccgtggtgccagcaccactgcctccaccctgtggctcctctgcccacctgctgcctccagtgcccggcggctgagaattc 126 DNA PAT source 1..126 mol_type other DNA organism synthetic construct misc_feature 1..126 note 41BB intracellular signaling domain (DNA sequence) aagcgcggtcggaagaagctgctgtacatctttaagcaacccttcatgaggcctgtgcagactactcaagaggaggacggctgttcatgccggttcccagaggaggaggaaggcggctgcgaactg 1071 DNA PAT source 1..1071 mol_type other DNA organism synthetic construct misc_feature 1..1071 note the nucleic acid molecule of example 1-2 ttcgaagccaccatgatcccagccgtggtgctgctgctgctgctgctggtggagcaggccgccgccctgggagagccccagctgtgctacatcctggacgccatcctgttcctgtacggcatcgtgctgaccctgctgtattgtaggctgaagatccaggtgcgcaaggccgccatcacatcttacgagaagagcgatggcgtgtataccggcctgagcacaagaaaccaggagacatacgagacactgaagcacgagaagccacctcagaagcgcggtcggaagaagctgctgtacatctttaagcaacccttcatgaggcctgtgcagactactcaagaggaggacggctgttcatgccggttcccagaggaggaggaaggcggctgcgaactgggctctggagagggaagaggcagcctgctgacctgcggcgacgtggaggagaatcctggcccaatggcctggatgctgctgctgatcctgatcatggtgcaccctggctcttgcgcactgtgggtgagccagccaccagagatccgcacactggagggcagctccgccttcctgccatgttcctttaacgcatctcagggccggctggcaatcggctccgtgacctggtttagagacgaggtggtgcccggcaaggaggtgaggaatggcacacccgagttcaggggccgcctggcacctctggcctctagccggtttctgcacgatcaccaggccgagctgcacatccgggacgtgagaggccacgatgcctctatctacgtgtgccgggtggaggtgctgggcctgggagtgggcaccggcaacggcacacggctggtggtggagaaggagcaccctcagctgggagcaggcaccgtgctgctgctgagggccggcttctatgccgtgagctttctgtccgtggccgtgggctccaccgtgtactatcagggcaagtgcctgacatggaaaggcccccggagacagctgccagccgtggtgccagcaccactgcctccaccctgtggctcctctgcccacctgctgcctccagtgcccggcggctgagaattc 945 DNA PAT source 1..945 mol_type other DNA organism synthetic construct misc_feature 1..945 note the nucleic acid molecule of comparative example 1 ttcgaagccaccatgatcccagccgtggtgctgctgctgctgctgctggtggagcaggccgccgccctgggagagccccagctgtgctacatcctggacgccatcctgttcctgtacggcatcgtgctgaccctgctgtattgtaggctgaagatccaggtgcgcaaggccgccatcacatcttacgagaagagcgatggcgtgtataccggcctgagcacaagaaaccaggagacatacgagacactgaagcacgagaagccacctcagggctctggagagggaagaggcagcctgctgacctgcggcgacgtggaggagaatcctggcccaatggcctggatgctgctgctgatcctgatcatggtgcaccctggctcttgcgcactgtgggtgagccagccaccagagatccgcacactggagggcagctccgccttcctgccatgttcctttaacgcatctcagggccggctggcaatcggctccgtgacctggtttagagacgaggtggtgcccggcaaggaggtgaggaatggcacacccgagttcaggggccgcctggcacctctggcctctagccggtttctgcacgatcaccaggccgagctgcacatccgggacgtgagaggccacgatgcctctatctacgtgtgccgggtggaggtgctgggcctgggagtgggcaccggcaacggcacacggctggtggtggagaaggagcaccctcagctgggagcaggcaccgtgctgctgctgagggccggcttctatgccgtgagctttctgtccgtggccgtgggctccaccgtgtactatcagggcaagtgcctgacatggaaaggcccccggagacagctgccagccgtggtgccagcaccactgcctccaccctgtggctcctctgcccacctgctgcctccagtgcccggcggctgagaattc 720 DNA PAT source 1..720 mol_type other DNA organism synthetic construct misc_feature 1..720 note SS1 scfv caggtgcagctccagcagtccggcccagagctggagaagcctggcgcctctgtgaagctgagctgtaaggccagcggctactccttcaccggctatacaatgaactgggtgaagcagtcccacggcaagtctctggagtggatcggcctgatcaccccctacaacggcgccagctcctataatcagaagtttcgcggcaaggccaccctgacagtggataagtctagctccaccgcctacatggacctgctgtctctgacaagcgaggattccgccgtgtacttctgcgccagaggcggctatgacggcagaggctttgattactggggccagggcaccacagtgaccgtgtctagcggcgtgggcggctctggaggaggaggcagcggcggaggaggctccgacatcgagctgacacagtccccagcaatcatgtctgccagccccggcgagaaggtgaccatgacatgttccgcctcctctagcgtgtcttacatgcactggtatcagcagaagtctggcaccagccctaagaggtggatctatgatacaagcaagctggcatccggcgtgccaggccgcttctccggctctggcagcggcaattcctactctctgaccatctcctctgtggaggccgaggacgatgccacatactattgccagcagtggagcaagcacccactgacctttggcgccggcacaaagctggagatcaag 225 DNA PAT source 1..225 mol_type other DNA organism synthetic construct misc_feature 1..225 note NKp30 without Ig-like domain (DNA sequence) gtggagaaggagcaccctcagctgggagcaggcaccgtgctgctgctgagggccggcttctatgccgtgagctttctgtccgtggccgtgggctccaccgtgtactatcagggcaagtgcctgacatggaaaggcccccggagacagctgccagccgtggtgccagcaccactgcctccaccctgtggctcctctgcccacctgctgcctccagtgcccggcggc 1566 DNA PAT source 1..1566 mol_type other DNA organism synthetic construct misc_feature 1..1566 note the nucleic acid molecule of example 2 atgattccagcagtggtcttgctcttactccttttggttgaacaagcagcggccctgggagagcctcagctctgctatatcctggatgccatcctgtttctgtatggaattgtcctcaccctcctctactgtcgactgaagatccaagtgcgaaaggcagctataaccagctatgagaaatcagatggtgtttacacgggcctgagcaccaggaaccaggagacttacgagactctgaagcatgagaaaccaccacagggctctggagagggaagaggcagcctgctgacctgcggcgacgtggaggagaatcctggcccaatcgatgccaccatcgatgccaccatggccttaccagtgaccgccttgctcctgccgctggccttgctgctccacgccgccaggccgcaggtgcagctccagcagtccggcccagagctggagaagcctggcgcctctgtgaagctgagctgtaaggccagcggctactccttcaccggctatacaatgaactgggtgaagcagtcccacggcaagtctctggagtggatcggcctgatcaccccctacaacggcgccagctcctataatcagaagtttcgcggcaaggccaccctgacagtggataagtctagctccaccgcctacatggacctgctgtctctgacaagcgaggattccgccgtgtacttctgcgccagaggcggctatgacggcagaggctttgattactggggccagggcaccacagtgaccgtgtctagcggcgtgggcggctctggaggaggaggcagcggcggaggaggctccgacatcgagctgacacagtccccagcaatcatgtctgccagccccggcgagaaggtgaccatgacatgttccgcctcctctagcgtgtcttacatgcactggtatcagcagaagtctggcaccagccctaagaggtggatctatgatacaagcaagctggcatccggcgtgccaggccgcttctccggctctggcagcggcaattcctactctctgaccatctcctctgtggaggccgaggacgatgccacatactattgccagcagtggagcaagcacccactgacctttggcgccggcacaaagctggagatcaagactagtggcggcggaggctctggcggcggcggcagcggcggcggaggctccgctagcgtggagaaggagcaccctcagctgggagcaggcaccgtgctgctgctgagggccggcttctatgccgtgagctttctgtccgtggccgtgggctccaccgtgtactatcagggcaagtgcctgacatggaaaggcccccggagacagctgccagccgtggtgccagcaccactgcctccaccctgtggctcctctgcccacctgctgcctccagtgcccggcggctacttcctgggccggctggtccctcgggggcgaggggctgcggaggcagcgacccggaaacagcgtatcactgagaccgagtcgccttatcaggagctccagggtcagaggtcggatgtctacagcgacctcaacacacagaggccgtattacaaa 207 DNA PAT source 1..207 mol_type other DNA organism synthetic construct misc_feature 1..207 note transmembrane domain of CD8 (DNA sequence) accactaccccagcaccgaggccacccaccccggctcctaccatcgcctcccagcctctgtccctgcgtccggaggcatgtagacccgcagctggtggggccgtgcatacccggggtcttgacttcgcctgcgatatctacatttgggcccctctggctggtacttgcggggtcctgctgctttcactcgtgatcactctttactgt 336 DNA PAT source 1..336 mol_type other DNA organism synthetic construct misc_feature 1..336 note CD3zeta signaling domain (DNA sequence) cgcgtgaaattcagccgcagcgcagatgctccagcctacaagcaggggcagaaccagctctacaacgaactcaatcttggtcggagagaggagtacgacgtgctggacaagcggagaggacgggacccagaaatgggcgggaagccgcgcagaaagaatccccaagagggcctgtacaacgagctccaaaaggataagatggcagaagcctatagcgagattggtatgaaaggggaacgcagaagaggcaaaggccacgacggactgtaccagggactcagcaccgccaccaaggacacctatgacgctcttcacatgcaggccctgccgcctcgg 1479 DNA PAT source 1..1479 mol_type other DNA organism synthetic construct misc_feature 1..1479 note the nucleic acid molecule of comparative example 2 atcgatgccaccatcgatgccaccatggccttaccagtgaccgccttgctcctgccgctggccttgctgctccacgccgccaggccgcaggtgcagctccagcagtccggcccagagctggagaagcctggcgcctctgtgaagctgagctgtaaggccagcggctactccttcaccggctatacaatgaactgggtgaagcagtcccacggcaagtctctggagtggatcggcctgatcaccccctacaacggcgccagctcctataatcagaagtttcgcggcaaggccaccctgacagtggataagtctagctccaccgcctacatggacctgctgtctctgacaagcgaggattccgccgtgtacttctgcgccagaggcggctatgacggcagaggctttgattactggggccagggcaccacagtgaccgtgtctagcggcgtgggcggctctggaggaggaggcagcggcggaggaggctccgacatcgagctgacacagtccccagcaatcatgtctgccagccccggcgagaaggtgaccatgacatgttccgcctcctctagcgtgtcttacatgcactggtatcagcagaagtctggcaccagccctaagaggtggatctatgatacaagcaagctggcatccggcgtgccaggccgcttctccggctctggcagcggcaattcctactctctgaccatctcctctgtggaggccgaggacgatgccacatactattgccagcagtggagcaagcacccactgacctttggcgccggcacaaagctggagatcaagaccactaccccagcaccgaggccacccaccccggctcctaccatcgcctcccagcctctgtccctgcgtccggaggcatgtagacccgcagctggtggggccgtgcatacccggggtcttgacttcgcctgcgatatctacatttgggcccctctggctggtacttgcggggtcctgctgctttcactcgtgatcactctttactgtaagcgcggtcggaagaagctgctgtacatctttaagcaacccttcatgaggcctgtgcagactactcaagaggaggacggctgttcatgccggttcccagaggaggaggaaggcggctgcgaactgcgcgtgaaattcagccgcagcgcagatgctccagcctacaagcaggggcagaaccagctctacaacgaactcaatcttggtcggagagaggagtacgacgtgctggacaagcggagaggacgggacccagaaatgggcgggaagccgcgcagaaagaatccccaagagggcctgtacaacgagctccaaaaggataagatggcagaagcctatagcgagattggtatgaaaggggaacgcagaagaggcaaaggccacgacggactgtaccagggactcagcaccgccaccaaggacacctatgacgctcttcacatgcaggccctgccgcctcggtaa 738 DNA PAT source 1..738 mol_type other DNA organism synthetic construct misc_feature 1..738 note m971 sfcv caggtacagctgcagcagtcaggtccaggactggtgaagccctcgcagaccctctcactcacctgtgccatctccggggacagtgtctctagcaacagtgctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtatctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagctgaactctgtgactcccgaggacacggctgtgtattactgtgcaagagaagtgactggggatctcgaggatgcttttgatatctggggccaagggacaatggtcaccgtctcctctggaggaggaggatccggaggaggaggaagcggaggaggaggaagcgacatccagatgacccagtctccatcgtccctgtctgcatctgtaggagacagagtcaccatcacttgccgggcaagccagaccatttggagctacttaaattggtatcagcagagaccagggaaagcccctaacctcctgatctatgctgcatccagtttgcaaagtggggtcccatcaaggttcagtggcaggggatctgggacagatttcactctcaccatcagcagtctgcaagctgaagattttgcaacttactactgtcaacagagttacagtatccctcagacttttggccaggggaccaagctggagatcaaa 1746 DNA PAT source 1..1746 mol_type other DNA organism synthetic construct misc_feature 1..1746 note the nucleic acid molecule of example 3 atgattccagcagtggtcttgctcttactccttttggttgaacaagcagcggccctgggagagcctcagctctgctatatcctggatgccatcctgtttctgtatggaattgtcctcaccctcctctactgtcgactgaagatccaagtgcgaaaggcagctataaccagctatgagaaatcagatggtgtttacacgggcctgagcaccaggaaccaggagacttacgagactctgaagcatgagaaaccaccacagatgattccagcagtggtcttgctcttactccttttggttgaacaagcagcggccctgggagagcctcagctctgctatatcctggatgccatcctgtttctgtatggaattgtcctcaccctcctctactgtcgactgaagatccaagtgcgaaaggcagctataaccagctatgagaaatcagatggtgtttacacgggcctgagcaccaggaaccaggagacttacgagactctgaagcatgagaaaccaccacagggctctggagagggaagaggcagcctgctgacctgcggcgacgtggaggagaatcctggcccaatcgatgccaccatcgatgccaccatggccttaccagtgaccgccttgctcctgccgctggccttgctgctccacgccgccaggccgcaggtacagctgcagcagtcaggtccaggactggtgaagccctcgcagaccctctcactcacctgtgccatctccggggacagtgtctctagcaacagtgctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtatctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagctgaactctgtgactcccgaggacacggctgtgtattactgtgcaagagaagtgactggggatctcgaggatgcttttgatatctggggccaagggacaatggtcaccgtctcctctggaggaggaggatccggaggaggaggaagcggaggaggaggaagcgacatccagatgacccagtctccatcgtccctgtctgcatctgtaggagacagagtcaccatcacttgccgggcaagccagaccatttggagctacttaaattggtatcagcagagaccagggaaagcccctaacctcctgatctatgctgcatccagtttgcaaagtggggtcccatcaaggttcagtggcaggggatctgggacagatttcactctcaccatcagcagtctgcaagctgaagattttgcaacttactactgtcaacagagttacagtatccctcagacttttggccaggggaccaagctggagatcaaaattgaagttatgtatcctcctccttacctagacaatgagaagagcaatggaaccattatccatgtgaaagggaaacacctttgtccaagtcccctatttcccggaccttctaagcccgtggagaaggagcaccctcagctgggagcaggcaccgtgctgctgctgagggccggcttctatgccgtgagctttctgtccgtggccgtgggctccaccgtgtactatcagggcaagtgcctgacatggaaaggcccccggagacagctgccagccgtggtgccagcaccactgcctccaccctgtggctcctctgcccacctgctgcctccagtgcccggcggc 1497 DNA PAT source 1..1497 mol_type other DNA organism synthetic construct misc_feature 1..1497 note the nucleic acid molecule of comparative example 3-1 atcgatgccaccatcgatgccaccatggccttaccagtgaccgccttgctcctgccgctggccttgctgctccacgccgccaggccgcaggtacagctgcagcagtcaggtccaggactggtgaagccctcgcagaccctctcactcacctgtgccatctccggggacagtgtctctagcaacagtgctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtatctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagctgaactctgtgactcccgaggacacggctgtgtattactgtgcaagagaagtgactggggatctcgaggatgcttttgatatctggggccaagggacaatggtcaccgtctcctctggaggaggaggatccggaggaggaggaagcggaggaggaggaagcgacatccagatgacccagtctccatcgtccctgtctgcatctgtaggagacagagtcaccatcacttgccgggcaagccagaccatttggagctacttaaattggtatcagcagagaccagggaaagcccctaacctcctgatctatgctgcatccagtttgcaaagtggggtcccatcaaggttcagtggcaggggatctgggacagatttcactctcaccatcagcagtctgcaagctgaagattttgcaacttactactgtcaacagagttacagtatccctcagacttttggccaggggaccaagctggagatcaaaaccactaccccagcaccgaggccacccaccccggctcctaccatcgcctcccagcctctgtccctgcgtccggaggcatgtagacccgcagctggtggggccgtgcatacccggggtcttgacttcgcctgcgatatctacatttgggcccctctggctggtacttgcggggtcctgctgctttcactcgtgatcactctttactgtaagcgcggtcggaagaagctgctgtacatctttaagcaacccttcatgaggcctgtgcagactactcaagaggaggacggctgttcatgccggttcccagaggaggaggaaggcggctgcgaactgcgcgtgaaattcagccgcagcgcagatgctccagcctacaagcaggggcagaaccagctctacaacgaactcaatcttggtcggagagaggagtacgacgtgctggacaagcggagaggacgggacccagaaatgggcgggaagccgcgcagaaagaatccccaagagggcctgtacaacgagctccaaaaggataagatggcagaagcctatagcgagattggtatgaaaggggaacgcagaagaggcaaaggccacgacggactgtaccagggactcagcaccgccaccaaggacacctatgacgctcttcacatgcaggccctgccgcctcggtaa 1488 DNA PAT source 1..1488 mol_type other DNA organism synthetic construct misc_feature 1..1488 note the nucleic acid molecule of comparative example 3-2 atgattccagcagtggtcttgctcttactccttttggttgaacaagcagcggccctgggagagcctcagctctgctatatcctggatgccatcctgtttctgtatggaattgtcctcaccctcctctactgtcgactgaagatccaagtgcgaaaggcagctataaccagctatgagaaatcagatggtgtttacacgggcctgagcaccaggaaccaggagacttacgagactctgaagcatgagaaaccaccacagggctctggagagggaagaggcagcctgctgacctgcggcgacgtggaggagaatcctggcccaatcgatgccaccatcgatgccaccatggccttaccagtgaccgccttgctcctgccgctggccttgctgctccacgccgccaggccgcaggtacagctgcagcagtcaggtccaggactggtgaagccctcgcagaccctctcactcacctgtgccatctccggggacagtgtctctagcaacagtgctgcttggaactggatcaggcagtccccatcgagaggccttgagtggctgggaaggacatactacaggtccaagtggtataatgattatgcagtatctgtgaaaagtcgaataaccatcaacccagacacatccaagaaccagttctccctgcagctgaactctgtgactcccgaggacacggctgtgtattactgtgcaagagaagtgactggggatctcgaggatgcttttgatatctggggccaagggacaatggtcaccgtctcctctggaggaggaggatccggaggaggaggaagcggaggaggaggaagcgacatccagatgacccagtctccatcgtccctgtctgcatctgtaggagacagagtcaccatcacttgccgggcaagccagaccatttggagctacttaaattggtatcagcagagaccagggaaagcccctaacctcctgatctatgctgcatccagtttgcaaagtggggtcccatcaaggttcagtggcaggggatctgggacagatttcactctcaccatcagcagtctgcaagctgaagattttgcaacttactactgtcaacagagttacagtatccctcagacttttggccaggggaccaagctggagatcaaaattgaagttatgtatcctcctccttacctagacaatgagaagagcaatggaaccattatccatgtgaaagggaaacacctttgtccaagtcccctatttcccggaccttctaagcccgtggagaaggagcaccctcagctgggagcaggcaccgtgctgctgctgagggccggcttctatgccgtgagctttctgtccgtggccgtgggctccaccgtgtactatcagggcaagtgcctgacatggaaaggcccccggagacagctgccagccgtggtgccagcaccactgcctccaccctgtggctcctctgcccacctgctgcctccagtgcccggcggc 2208 DNA PAT source 1..2208 mol_type genomic DNA organism Homo sapiens misc_feature 1..2208 note truncated CD22 fragment (DNA sequence) atgcatctcctcggcccctggctcctgctcctggttctagaatacttggctttctctgactcaagtaaatgggtttttgagcaccctgaaaccctctacgcctgggagggggcctgcgtctggatcccctgcacctacagagccctagatggtgacctggaaagcttcatcctgttccacaatcctgagtataacaagaacacctcgaagtttgatgggacaagactctatgaaagcacaaaggatgggaaggttccttctgagcagaaaagggtgcaattcctgggagacaagaataagaactgcacactgagtatccacccggtgcacctcaatgacagtggtcagctggggctgaggatggagtccaagactgagaaatggatggaacgaatacacctcaatgtctctgaaaggccttttccacctcatatccagctccctccagaaattcaagagtcccaggaagtcactctgacctgcttgctgaatttctcctgctatgggtatccgatccaattgcagtggctcctagagggggttccaatgaggcaggctgctgtcacctcgacctccttgaccatcaagtctgtcttcacccggagcgagctcaagttctccccacagtggagtcaccatgggaagattgtgacctgccagcttcaggatgcagatgggaagttcctctccaatgacacggtgcagctgaacgtgaagcacaccccgaagttggagatcaaggtcactcccagtgatgccatagtgagggagggggactctgtgaccatgacctgcgaggtcagcagcagcaacccggagtacacgacggtatcctggctcaaggatgggacctcgctgaagaagcagaatacattcacgctaaacctgcgcgaagtgaccaaggaccagagtgggaagtactgctgtcaggtctccaatgacgtgggcccgggaaggtcggaagaagtgttcctgcaagtgcagtatgccccggaaccttccacggttcagatcctccactcaccggctgtggagggaagtcaagtcgagtttctttgcatgtcactggccaatcctcttccaacaaattacacgtggtaccacaatgggaaagaaatgcagggaaggacagaggagaaagtccacatcccaaagatcctcccctggcacgctgggacttattcctgtgtggcagaaaacattcttggtactggacagaggggcccgggagctgagctggatgtccagtatcctcccaagaaggtgaccacagtgattcaaaaccccatgccgattcgagaaggagacacagtgaccctttcctgtaactacaattccagtaaccccagtgttacccggtatgaatggaaaccccatggcgcctgggaggagccatcgcttggggtgctgaagatccaaaacgttggctgggacaacacaaccatcgcctgcgcagcttgtaatagttggtgctcgtgggcctcccctgtcgccctgaatgtccagtatgccccccgagacgtgagggtccggaaaatcaagcccctttccgagattcactctggaaactcggtcagcctccaatgtgacttctcaagcagccaccccaaagaagtccagttcttctgggagaaaaatggcaggcttctggggaaagaaagccagctgaattttgactccatctccccagaagatgctgggagttacagctgctgggtgaacaactccataggacagacagcgtccaaggcctggacacttgaagtgctgtatgcacccaggaggctgcgtgtgtccatgagcccgggggaccaagtgatggaggggaagagtgcaaccctgacctgtgagagcgacgccaaccctcccgtctcccactacacctggtttgactggaataaccaaagcctcccctaccacagccagaagctgagattggagccggtgaaggtccagcactcgggtgcctactggtgccaggggaccaacagtgtgggcaagggccgttcgcctctcagcaccctcaccgtctactatagcccggagaccatcggcaggcgagtggctgtgggactcgggtcctgcctcgccatcctcatcctggcaatctgtgggctcaagctccagcgacgttggaagaggacacagagccagcaggggcttcaggagaattccagcggccagagcttctttgtgaggaataaaaag 726 DNA PAT source 1..726 mol_type other DNA organism synthetic construct misc_feature 1..726 note FMC63 scfv (DNA sequence) gacatccagatgacacagactacatcctccctgtctgcctctctgggagacagagtcaccatcagttgcagggcaagtcaggacattagtaaatatttaaattggtatcagcagaaaccagatggaactgttaaactcctgatctaccatacatcaagattacactcaggagtcccatcaaggttcagtggcagtgggtctggaacagattattctctcaccattagcaacctggagcaagaagatattgccacttacttttgccaacagggtaatacgcttccgtacacgttcggaggggggaccaagctggagatcacaggtggcggtggctcgggcggtggtgggtcgggtggcggcggatctgaggtgaaactgcaggagtcaggacctggcctggtggcgccctcacagagcctgtccgtcacatgcactgtctcaggggtctcattacccgactatggtgtaagctggattcgccagcctccacgaaagggtctggagtggctgggagtaatatggggtagtgaaaccacatactataattcagctctcaaatccagactgaccatcatcaaggacaactccaagagccaagttttcttaaaaatgaacagtctgcaaactgatgacacagccatttactactgtgccaaacattattactacggtggtagctatgctatggactactggggccaaggaacctcagtcaccgtctcctca 1551 DNA PAT source 1..1551 mol_type other DNA organism synthetic construct misc_feature 1..1551 note the nucleic acid molecule of example 4 atgattccagcagtggtcttgctcttactccttttggttgaacaagcagcggccctgggagagcctcagctctgctatatcctggatgccatcctgtttctgtatggaattgtcctcaccctcctctactgtcgactgaagatccaagtgcgaaaggcagctataaccagctatgagaaatcagatggtgtttacacgggcctgagcaccaggaaccaggagacttacgagactctgaagcatgagaaaccaccacagtacttcctgggccggctggtccctcgggggcgaggggctgcggaggcagcgacccggaaacagcgtatcactgagaccgagtcgccttatcaggagctccagggtcagaggtcggatgtctacagcgacctcaacacacagaggccgtattacaaaggctctggagagggaagaggcagcctgctgacctgcggcgacgtggaggagaatcctggcccaatcgatgccaccatcgatgccaccatggccttaccagtgaccgccttgctcctgccgctggccttgctgctccacgccgccaggccggacatccagatgacacagactacatcctccctgtctgcctctctgggagacagagtcaccatcagttgcagggcaagtcaggacattagtaaatatttaaattggtatcagcagaaaccagatggaactgttaaactcctgatctaccatacatcaagattacactcaggagtcccatcaaggttcagtggcagtgggtctggaacagattattctctcaccattagcaacctggagcaagaagatattgccacttacttttgccaacagggtaatacgcttccgtacacgttcggaggggggaccaagctggagatcacaggtggcggtggctcgggcggtggtgggtcgggtggcggcggatctgaggtgaaactgcaggagtcaggacctggcctggtggcgccctcacagagcctgtccgtcacatgcactgtctcaggggtctcattacccgactatggtgtaagctggattcgccagcctccacgaaagggtctggagtggctgggagtaatatggggtagtgaaaccacatactataattcagctctcaaatccagactgaccatcatcaaggacaactccaagagccaagttttcttaaaaatgaacagtctgcaaactgatgacacagccatttactactgtgccaaacattattactacggtggtagctatgctatggactactggggccaaggaacctcagtcaccgtctcctcagagtccaaatatggtcccccatgcccatcatgcccagtggagaaggagcaccctcagctgggagcaggcaccgtgctgctgctgagggccggcttctatgccgtgagctttctgtccgtggccgtgggctccaccgtgtactatcagggcaagtgcctgacatggaaaggcccccggagacagctgccagccgtggtgccagcaccactgcctccaccctgtggctcctctgcccacctgctgcctccagtgcccggcggc 1485 DNA PAT source 1..1485 mol_type other DNA organism synthetic construct misc_feature 1..1485 note the nucleic acid molecule of comparative example 4 atcgatgccaccatcgatgccaccatggccttaccagtgaccgccttgctcctgccgctggccttgctgctccacgccgccaggccggacatccagatgacacagactacatcctccctgtctgcctctctgggagacagagtcaccatcagttgcagggcaagtcaggacattagtaaatatttaaattggtatcagcagaaaccagatggaactgttaaactcctgatctaccatacatcaagattacactcaggagtcccatcaaggttcagtggcagtgggtctggaacagattattctctcaccattagcaacctggagcaagaagatattgccacttacttttgccaacagggtaatacgcttccgtacacgttcggaggggggaccaagctggagatcacaggtggcggtggctcgggcggtggtgggtcgggtggcggcggatctgaggtgaaactgcaggagtcaggacctggcctggtggcgccctcacagagcctgtccgtcacatgcactgtctcaggggtctcattacccgactatggtgtaagctggattcgccagcctccacgaaagggtctggagtggctgggagtaatatggggtagtgaaaccacatactataattcagctctcaaatccagactgaccatcatcaaggacaactccaagagccaagttttcttaaaaatgaacagtctgcaaactgatgacacagccatttactactgtgccaaacattattactacggtggtagctatgctatggactactggggccaaggaacctcagtcaccgtctcctcaaccactaccccagcaccgaggccacccaccccggctcctaccatcgcctcccagcctctgtccctgcgtccggaggcatgtagacccgcagctggtggggccgtgcatacccggggtcttgacttcgcctgcgatatctacatttgggcccctctggctggtacttgcggggtcctgctgctttcactcgtgatcactctttactgtaagcgcggtcggaagaagctgctgtacatctttaagcaacccttcatgaggcctgtgcagactactcaagaggaggacggctgttcatgccggttcccagaggaggaggaaggcggctgcgaactgcgcgtgaaattcagccgcagcgcagatgctccagcctacaagcaggggcagaaccagctctacaacgaactcaatcttggtcggagagaggagtacgacgtgctggacaagcggagaggacgggacccagaaatgggcgggaagccgcgcagaaagaatccccaagagggcctgtacaacgagctccaaaaggataagatggcagaagcctatagcgagattggtatgaaaggggaacgcagaagaggcaaaggccacgacggactgtaccagggactcagcaccgccaccaaggacacctatgacgctcttcacatgcaggccctgccgcctcggtaa 1026 DNA PAT source 1..1026 mol_type other DNA organism synthetic construct misc_feature 1..1026 note truncated CD19 fragment (DNA sequence) atgccacctcctcgcctcctcttcttcctcctcttcctcacccccatggaagtcaggcccgaggaacctctagtggtgaaggtggaagagggagataacgctgtgctgcagtgcctcaaggggacctcagatggccccactcagcagctgacctggtctcgggagtccccgcttaaacccttcttaaaactcagcctggggctgccaggcctgggaatccacatgaggcccctggccatctggcttttcatcttcaacgtctctcaacagatggggggcttctacctgtgccagccggggcccccctctgagaaggcctggcagcctggctggacagtcaatgtggagggcagcggggagctgttccggtggaatgtttcggacctaggtggcctgggctgtggcctgaagaacaggtcctcagagggccccagctccccttccgggaagctcatgagccccaagctgtatgtgtgggccaaagaccgccctgagatctgggagggagagcctccgtgtctcccaccgagggacagcctgaaccagagcctcagccaggacctcaccatggcccctggctccacactctggctgtcctgtggggtaccccctgactctgtgtccaggggccccctctcctggacccatgtgcaccccaaggggcctaagtcattgctgagcctagagctgaaggacgatcgcccggccagagatatgtgggtaatggagacgggtctgttgttgccccgggccacagctcaagacgctggaaagtattattgtcaccgtggcaacctgaccatgtcattccacctggagatcactgctcggccagtactatggcactggctgctgaggactggtggctggaaggtctcagctgtgactttggcttatctgatcttctgcctgtgttcccttgtgggcattcttcatcttcaaagagccctggtcctgaggaggaaaagaaagcgaatgactgaccccaccaggagattcttcaaagtgacgcctcccccaggaagc