X23072 US US 63/244,427 2021-09-15 Dermira, Inc. IL-13 INHIBITORS FOR THE TREATMENT OF PRURIGO NODULARIS 10 5 AA PAT REGION 1..5 note Synthetic Construct source 1..5 mol_type protein organism synthetic construct AYSVN 16 AA PAT REGION 1..16 note Synthetic Construct source 1..16 mol_type protein organism synthetic construct MIWGDGKIVYNSALKS 10 AA PAT REGION 1..10 note Synthetic Construct source 1..10 mol_type protein organism synthetic construct DGYYPYAMDN 15 AA PAT REGION 1..15 note Synthetic Construct source 1..15 mol_type protein organism synthetic construct RASKSVDSYGNSFMH 7 AA PAT REGION 1..7 note Synthetic Construct source 1..7 mol_type protein organism synthetic construct LASNLES 9 AA PAT REGION 1..9 note Synthetic Construct source 1..9 mol_type protein organism synthetic construct QQNNEDPRT 117 AA PAT REGION 1..117 note Synthetic Construct source 1..117 mol_type protein organism synthetic construct VTLRESGPALVKPTQTLTLTCTVSGFSLSAYSVNWIRQPPGKALEWLAMIWGDGKIVYNSALKSRLTISKDTSKNQVVLTMTNMDPVDTATYYCAGDGYYPYAMDNWGQGSLVTVSS 111 AA PAT REGION 1..111 note Synthetic Construct source 1..111 mol_type protein organism synthetic construct DIVMTQSPDSLSVSLGERATINCRASKSVDSYGNSFMHWYQQKPGQPPKLLIYLASNLESGVPDRFSGSGSGTDFTLTISSLQAEDVAVYYCQQNNEDPRTFGGGTKVEIK 445 AA PAT REGION 1..445 note Synthetic Construct SITE 1 note MISC_FEATURE - Xaa at position 1 is Q, pE, or absent SITE 444 note MISC_FEATURE - Xaa at position 444 is G or absent SITE 445 note MISC_FEATURE - Xaa at position 445 is K or absent source 1..445 mol_type protein organism synthetic construct XVTLRESGPALVKPTQTLTLTCTVSGFSLSAYSVNWIRQPPGKALEWLAMIWGDGKIVYNSALKSRLTISKDTSKNQVVLTMTNMDPVDTATYYCAGDGYYPYAMDNWGQGSLVTVSSASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTKTYTCNVDHKPSNTKVDKRVESKYGPPCPPCPAPEFLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSQEDPEVQFNWYVDGVEVHNAKTKPREEQFNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKGLPSSIEKTISKAKGQPREPQVYTLPPSQEEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSRLTVDKSRWQEGNVFSCSVMHEALHNHYTQKSLSLSLXX 218 AA PAT REGION 1..218 note Synthetic Construct source 1..218 mol_type protein organism synthetic construct DIVMTQSPDSLSVSLGERATINCRASKSVDSYGNSFMHWYQQKPGQPPKLLIYLASNLESGVPDRFSGSGSGTDFTLTISSLQAEDVAVYYCQQNNEDPRTFGGGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC