CN 091866-8001WO01 CN 202311686000 .7 2023-12-11 杭州鼎乐新为生物科技有限公司 Hangzhou Dinovate Biotech Co., Ltd. 张睿 ZHANG, Rui SIRNA MOLECULE FOR INHIBITING PCSK9 EXPRESSION AND USE THEREOF 106 21 RNA PAT source 1..21 mol_type other RNA organism synthetic construct ctagacctgttttgcttttgt 23 RNA PAT source 1..23 mol_type other RNA organism synthetic construct acaaaagcaaaacaggtctagaa 19 RNA PAT source 1..19 mol_type other RNA organism synthetic construct ggtctggaatgcaaagtca 21 RNA PAT source 1..21 mol_type other RNA organism synthetic construct tgactttgcattccagacctg 19 RNA PAT source 1..19 mol_type other RNA organism synthetic construct ggtggaggtgtatctccta 21 RNA PAT source 1..21 mol_type other RNA organism synthetic construct taggagatacacctccaccag 19 RNA PAT source 1..19 mol_type other RNA organism synthetic construct cctacgtggtggtgctgaa 21 RNA PAT source 1..21 mol_type other RNA organism synthetic construct ttcagcaccaccacgtaggtg 19 RNA PAT source 1..19 mol_type other RNA organism synthetic construct ggactgtatggtcagcaca 21 RNA PAT source 1..21 mol_type other RNA organism synthetic construct tgtgctgaccatacagtcctg 19 RNA PAT source 1..19 mol_type other RNA organism synthetic construct gcacctgctttgtgtcaca 21 RNA PAT source 1..21 mol_type other RNA organism synthetic construct tgtgacacaaagcaggtgctg 19 RNA PAT source 1..19 mol_type other RNA organism synthetic construct gggtcatggtcaccgactt 21 RNA PAT source 1..21 mol_type other RNA organism synthetic construct aagtcggtgaccatgaccctg 19 RNA PAT source 1..19 mol_type other RNA organism synthetic construct ccaagcaagcagacattta 21 RNA PAT source 1..21 mol_type other RNA organism synthetic construct taaatgtctgcttgcttgggt 19 RNA PAT source 1..19 mol_type other RNA organism synthetic construct gtctggaatgcaaagtcaa 21 RNA PAT source 1..21 mol_type other RNA organism synthetic construct ttgactttgcattccagacct 19 RNA PAT source 1..19 mol_type other RNA organism synthetic construct caagcaagcagacatttat 21 RNA PAT source 1..21 mol_type other RNA organism synthetic construct ataaatgtctgcttgcttggg 19 RNA PAT source 1..19 mol_type other RNA organism synthetic construct ggttagcggcaccctcata 21 RNA PAT source 1..21 mol_type other RNA organism synthetic construct tatgagggtgccgctaaccgt 19 RNA PAT source 1..19 mol_type other RNA organism synthetic construct cctacttcacagaggaaga 21 RNA PAT source 1..21 mol_type other RNA organism synthetic construct tcttcctctgtgaagtagggg 19 RNA PAT source 1..19 mol_type other RNA organism synthetic construct cctgattaatggaggctta 21 RNA PAT source 1..21 mol_type other RNA organism synthetic construct taagcctccattaatcaggga 19 RNA PAT source 1..19 mol_type other RNA organism synthetic construct ccaagatcctgcatgtctt 21 RNA PAT source 1..21 mol_type other RNA organism synthetic construct aagacatgcaggatcttggtg 19 RNA PAT source 1..19 mol_type other RNA organism synthetic construct gagttgaggcagagactga 21 RNA PAT source 1..21 mol_type other RNA organism synthetic construct tcagtctctgcctcaactcgg 19 RNA PAT source 1..19 mol_type other RNA organism synthetic construct ggcagtgtgcagtggtgca 21 RNA PAT source 1..21 mol_type other RNA organism synthetic construct tgcaccactgcacactgccga 19 RNA PAT source 1..19 mol_type other RNA organism synthetic construct gaagcacccgagcacggaa 21 RNA PAT source 1..21 mol_type other RNA organism synthetic construct ttccgtgctcgggtgcttcgg 19 RNA PAT source 1..19 mol_type other RNA organism synthetic construct gggacgatgcctgcctcta 21 RNA PAT source 1..21 mol_type other RNA organism synthetic construct tagaggcaggcatcgtcccgg 19 RNA PAT source 1..19 mol_type other RNA organism synthetic construct ggtacagccgcgtcctcaa 21 RNA PAT source 1..21 mol_type other RNA organism synthetic construct ttgaggacgcggctgtaccca 19 RNA PAT source 1..19 mol_type other RNA organism synthetic construct cagaggaagaaacctggaa 21 RNA PAT source 1..21 mol_type other RNA organism synthetic construct ttccaggtttcttcctctgtg 19 RNA PAT source 1..19 mol_type other RNA organism synthetic construct ccaaagatgtcatcaatga 21 RNA PAT source 1..21 mol_type other RNA organism synthetic construct tcattgatgacatctttggca 19 RNA PAT source 1..19 mol_type other RNA organism synthetic construct gcatttcaccattcaaaca 21 RNA PAT source 1..21 mol_type other RNA organism synthetic construct tgtttgaatggtgaaatgccc 19 RNA PAT source 1..19 mol_type other RNA organism synthetic construct gcagaatgacttttattga 21 RNA PAT source 1..21 mol_type other RNA organism synthetic construct tcaataaaagtcattctgccc 19 RNA PAT source 1..19 mol_type other RNA organism synthetic construct ggaactttttccgttatca 21 RNA PAT source 1..21 mol_type other RNA organism synthetic construct tgataacggaaaaagttccat 19 RNA PAT source 1..19 mol_type other RNA organism synthetic construct gtaacttgaagatatttat 21 RNA PAT source 1..21 mol_type other RNA organism synthetic construct ataaatatcttcaagttacaa 19 RNA PAT source 1..19 mol_type other RNA organism synthetic construct gggttttgtagcattttta 21 RNA PAT source 1..21 mol_type other RNA organism synthetic construct taaaaatgctacaaaacccag 19 RNA PAT source 1..19 mol_type other RNA organism synthetic construct gtagcatttttattaatat 21 RNA PAT source 1..21 mol_type other RNA organism synthetic construct atattaataaaaatgctacaa 19 RNA PAT source 1..19 mol_type other RNA organism synthetic construct ggtcaccgacttcgagaat 21 RNA PAT source 1..21 mol_type other RNA organism synthetic construct attctcgaagtcggtgaccat 19 RNA PAT source 1..19 mol_type other RNA organism synthetic construct gaggcagagactgatccac 21 RNA PAT source 1..21 mol_type other RNA organism synthetic construct gtggatcagtctctgcctcaa 19 RNA PAT source 1..19 mol_type other RNA organism synthetic construct ggcagagactgatccactt 21 RNA PAT source 1..21 mol_type other RNA organism synthetic construct aagtggatcagtctctgcctc 19 RNA PAT source 1..19 mol_type other RNA organism synthetic construct gggcatttcaccattcaaa 21 RNA PAT source 1..21 mol_type other RNA organism synthetic construct tttgaatggtgaaatgcccca 19 RNA PAT source 1..19 mol_type other RNA organism synthetic construct gtttcctgagccaccttta 21 RNA PAT source 1..21 mol_type other RNA organism synthetic construct taaaggtggctcaggaaacca 19 RNA PAT source 1..19 mol_type other RNA organism synthetic construct gccacctttactctgctct 21 RNA PAT source 1..21 mol_type other RNA organism synthetic construct agagcagagtaaaggtggctc 19 RNA PAT source 1..19 mol_type other RNA organism synthetic construct tggtcaccgacttcgagaa 21 RNA PAT source 1..21 mol_type other RNA organism synthetic construct ttctcgaagtcggtgaccatg 18 RNA PAT source 1..18 mol_type other RNA organism synthetic construct ggtcacgacttcgagaat 21 RNA PAT source 1..21 mol_type other RNA organism synthetic construct attctcgaagtcggtgaccat 19 RNA PAT source 1..19 mol_type other RNA organism synthetic construct cagagtgaccaccgggaaa 21 RNA PAT source 1..21 mol_type other RNA organism synthetic construct tttcccggtggtcactctgta 19 RNA PAT source 1..19 mol_type other RNA organism synthetic construct cgtggaacctggagcggat 21 RNA PAT source 1..21 mol_type other RNA organism synthetic construct atccgctccaggttccacggg 19 RNA PAT source 1..19 mol_type other RNA organism synthetic construct ccgggacgtcagcactaca 21 RNA PAT source 1..21 mol_type other RNA organism synthetic construct tgtagtgctgacgtcccggct 21 RNA PAT source 1..21 mol_type other RNA organism synthetic construct caagcagacatttatcttttt 23 RNA PAT source 1..23 mol_type other RNA organism synthetic construct aaaaagataaatgtctgcttgct 21 RNA PAT source 1..21 mol_type other RNA organism synthetic construct caagcaagcagacatttatct 23 RNA PAT source 1..23 mol_type other RNA organism synthetic construct agataaatgtctgcttgcttggg 21 RNA PAT source 1..21 mol_type other RNA organism synthetic construct ttctagacctgttttgctttt 23 RNA PAT source 1..23 mol_type other RNA organism synthetic construct aaaagcaaaacaggtctagaaaa 21 RNA PAT source 1..21 mol_type other RNA organism synthetic construct tagacctgttttgcttttgta 23 RNA PAT source 1..23 mol_type other RNA organism synthetic construct tacaaaagcaaaacaggtctaga 21 RNA PAT source 1..21 mol_type other RNA organism synthetic construct ttttctagacctgttttgctt 23 RNA PAT source 1..23 mol_type other RNA organism synthetic construct aagcaaaacaggtctagaaaagt 21 RNA PAT source 1..21 mol_type other RNA organism synthetic construct aagcaagcagacatttatctt 23 RNA PAT source 1..23 mol_type other RNA organism synthetic construct aagataaatgtctgcttgcttgg 21 RNA PAT source 1..21 mol_type other RNA organism synthetic construct tgtaacttgaagatatttatt 23 RNA PAT source 1..23 mol_type other RNA organism synthetic construct aataaatatcttcaagttacaaa 21 RNA PAT source 1..21 mol_type other RNA organism synthetic construct tttctagacctgttttgcttt 23 RNA PAT source 1..23 mol_type other RNA organism synthetic construct aaagcaaaacaggtctagaaaag 21 RNA PAT source 1..21 mol_type other RNA organism synthetic construct ttttgtaacttgaagatattt 23 RNA PAT source 1..23 mol_type other RNA organism synthetic construct aaatatcttcaagttacaaaagc 21 RNA PAT source 1..21 mol_type other RNA organism synthetic construct cacccaagcaagcagacattt 23 RNA PAT source 1..23 mol_type other RNA organism synthetic construct aaatgtctgcttgcttgggtggg 21 RNA PAT source 1..21 mol_type other RNA organism synthetic construct ccaagcaagcagacatttatt 23 RNA PAT source 1..23 mol_type other RNA organism synthetic construct aataaatgtctgcttgcttgggt 21 RNA PAT source 1..21 mol_type other RNA organism synthetic construct cccaagcaagcagacatttat 23 RNA PAT source 1..23 mol_type other RNA organism synthetic construct ataaatgtctgcttgcttgggtg 19 RNA PAT source 1..19 mol_type other RNA organism synthetic construct agacctgttttgcttttgt 21 RNA PAT source 1..21 mol_type other RNA organism synthetic construct acaaaagcaaaacaggtctag 19 RNA PAT source 1..19 mol_type other RNA organism synthetic construct agacctgttttgcttttgt 21 RNA PAT source 1..21 mol_type other RNA organism synthetic construct acaaaagcaaaacaggtctag 21 RNA PAT source 1..21 mol_type other RNA organism synthetic construct ctagacctgttttgcttttgt 23 RNA PAT source 1..23 mol_type other RNA organism synthetic construct acaaaagcaaaacaggtctagaa