P22-239WO JP 2021-198818 2021-12-07 国立大学法人大阪大学 OSAKA UNIVERSITY 抗体又はその抗原結合性断片 76 5 AA PAT REGION 1..5 note 1 source 1..5 mol_type protein organism synthetic construct EYIIH 8 AA PAT REGION 1..8 note 2 source 1..8 mol_type protein organism synthetic construct GYTFTEYI 17 AA PAT REGION 1..17 note 3 source 1..17 mol_type protein organism synthetic construct WFYPGRGIIKYNEKFKD 8 AA PAT REGION 1..8 note 4 source 1..8 mol_type protein organism synthetic construct FYPGRGII 12 AA PAT REGION 1..12 note 5 source 1..12 mol_type protein organism synthetic construct HGITTATGAMDY 14 AA PAT REGION 1..14 note 6 source 1..14 mol_type protein organism synthetic construct ARHGITTATGAMDY 16 AA PAT REGION 1..16 note 7 source 1..16 mol_type protein organism synthetic construct RSSQSLLHSNGNTYLH 11 AA PAT REGION 1..11 note 8 source 1..11 mol_type protein organism synthetic construct QSLLHSNGNTY 7 AA PAT REGION 1..7 note 9 source 1..7 mol_type protein organism synthetic construct KVSNRFS 000 9 AA PAT REGION 1..9 note 11 source 1..9 mol_type protein organism synthetic construct SQSTHVPFT 9 AA PAT REGION 1..9 note 12 source 1..9 mol_type protein organism synthetic construct SQSTHVPFT 5 AA PAT REGION 1..5 note 13 source 1..5 mol_type protein organism synthetic construct SYAMS 8 AA PAT REGION 1..8 note 14 source 1..8 mol_type protein organism synthetic construct GITFSSYA 16 AA PAT REGION 1..16 note 15 source 1..16 mol_type protein organism synthetic construct SISSGGSTYYPDSVKG 7 AA PAT REGION 1..7 note 16 source 1..7 mol_type protein organism synthetic construct ISSGGST 9 AA PAT REGION 1..9 note 17 source 1..9 mol_type protein organism synthetic construct IWDGSSYGY 11 AA PAT REGION 1..11 note 18 source 1..11 mol_type protein organism synthetic construct VAIWDGSSYGY 16 AA PAT REGION 1..16 note 19 source 1..16 mol_type protein organism synthetic construct RSGQSLVHSNGKTYLH 11 AA PAT REGION 1..11 note 20 source 1..11 mol_type protein organism synthetic construct QSLVHSNGKTY 7 AA PAT REGION 1..7 note 21 source 1..7 mol_type protein organism synthetic construct KVSNRFS 000 9 AA PAT REGION 1..9 note 23 source 1..9 mol_type protein organism synthetic construct SQSTHVPFT 9 AA PAT REGION 1..9 note 24 source 1..9 mol_type protein organism synthetic construct SQSTHVPFT 5 AA PAT REGION 1..5 note 25 source 1..5 mol_type protein organism synthetic construct SYAMS 8 AA PAT REGION 1..8 note 26 source 1..8 mol_type protein organism synthetic construct GFIFSSYA 16 AA PAT REGION 1..16 note 27 source 1..16 mol_type protein organism synthetic construct SIGSGGTTYYPDSVRG 7 AA PAT REGION 1..7 note 28 source 1..7 mol_type protein organism synthetic construct IGSGGTT 9 AA PAT REGION 1..9 note 29 source 1..9 mol_type protein organism synthetic construct IWDGSSHGY 11 AA PAT REGION 1..11 note 30 source 1..11 mol_type protein organism synthetic construct AAIWDGSSHGY 16 AA PAT REGION 1..16 note 31 source 1..16 mol_type protein organism synthetic construct RSSQNLVHSNGNTYLH 11 AA PAT REGION 1..11 note 32 source 1..11 mol_type protein organism synthetic construct QNLVHSNGNTY 7 AA PAT REGION 1..7 note 33 source 1..7 mol_type protein organism synthetic construct KVSNRFS 000 9 AA PAT REGION 1..9 note 35 source 1..9 mol_type protein organism synthetic construct SQSTHVPYT 9 AA PAT REGION 1..9 note 36 source 1..9 mol_type protein organism synthetic construct SQSTHVPYT 5 AA PAT REGION 1..5 note 37 source 1..5 mol_type protein organism synthetic construct SYAMS 8 AA PAT REGION 1..8 note 38 source 1..8 mol_type protein organism synthetic construct GFTFSSYA 17 AA PAT REGION 1..17 note 39 source 1..17 mol_type protein organism synthetic construct SINSGGVTTYYPDSVKG 8 AA PAT REGION 1..8 note 40 source 1..8 mol_type protein organism synthetic construct INSGGVTT 9 AA PAT REGION 1..9 note 41 source 1..9 mol_type protein organism synthetic construct IWDGSSHGY 11 AA PAT REGION 1..11 note 42 source 1..11 mol_type protein organism synthetic construct AAIWDGSSHGY 16 AA PAT REGION 1..16 note 43 source 1..16 mol_type protein organism synthetic construct RSSQSLVHSNGNTYLH 11 AA PAT REGION 1..11 note 44 source 1..11 mol_type protein organism synthetic construct QSLVHSNGNTY 7 AA PAT REGION 1..7 note 45 source 1..7 mol_type protein organism synthetic construct KVSNRFS 000 9 AA PAT REGION 1..9 note 47 source 1..9 mol_type protein organism synthetic construct SQSTHVPYT 9 AA PAT REGION 1..9 note 48 source 1..9 mol_type protein organism synthetic construct SQSTHVPYT 5 AA PAT REGION 1..5 note 49 source 1..5 mol_type protein organism synthetic construct DAWMD 8 AA PAT REGION 1..8 note 50 source 1..8 mol_type protein organism synthetic construct GFTFSDAW 19 AA PAT REGION 1..19 note 51 source 1..19 mol_type protein organism synthetic construct EIRNKANNHATYFTESVKG 10 AA PAT REGION 1..10 note 52 source 1..10 mol_type protein organism synthetic construct IRNKANNHAT 5 AA PAT REGION 1..5 note 53 source 1..5 mol_type protein organism synthetic construct ATFVY 7 AA PAT REGION 1..7 note 54 source 1..7 mol_type protein organism synthetic construct TTATFVY 15 AA PAT REGION 1..15 note 55 source 1..15 mol_type protein organism synthetic construct RSSQSLVRNGITYLH 10 AA PAT REGION 1..10 note 56 source 1..10 mol_type protein organism synthetic construct QSLVRNGITY 7 AA PAT REGION 1..7 note 57 source 1..7 mol_type protein organism synthetic construct KVSNRFS 000 9 AA PAT REGION 1..9 note 59 source 1..9 mol_type protein organism synthetic construct SQTPHVPYT 9 AA PAT REGION 1..9 note 60 source 1..9 mol_type protein organism synthetic construct SQTPHVPYT 6 AA PAT REGION 1..6 note 61 source 1..6 mol_type protein organism synthetic construct TKVTKF 5 AA PAT REGION 1..5 note 62 source 1..5 mol_type protein organism synthetic construct EIKRL 6 AA PAT REGION 1..6 note 63 source 1..6 mol_type protein organism synthetic construct DEEIKR 6 AA PAT REGION 1..6 note 64 source 1..6 mol_type protein organism synthetic construct IKRLLQ 28 AA PAT source 1..28 mol_type protein organism Homo sapiens EVTKVTKFIEGGDGHLFEDEEIKRLLQG 809 AA PAT source 1..809 mol_type protein organism Homo sapiens MIPFLPMFSLLLLLIVNPINANNHYDKILAHSRIRGRDQGPNVCALQQILGTKKKYFSTCKNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDASKLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLKNGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDFIEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEALMKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHLIDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSMDQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQGRNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDAFKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVNDTLLVNELKSKESDIMTTNGVIHVVDKLLYPADTPVGNDQLLEILNKLIKYIQIKFVRGSTFKEIPVTVYRPTLTKVKIEGEPEFRLIKEGETITEVIHGEPIIKKYTKIIDGVPVEITEKETREERIITGPEIKYTRISTGGGETEETLKKLLQEEVTKVTKFIEGGDGHLFEDEEIKRLLQGDTPVRKLQANKKVQGSRRRLREGRSQ 121 AA PAT REGION 1..121 note 67 source 1..121 mol_type protein organism synthetic construct KVQLVQSGAEVVKPGASVKLSCKASGYTFTEYIIHWVKQASGQGLEWIGWFYPGRGIIKYNEKFKDKATLTADKSISTVYMDLSRLRSEDTAVYFCARHGITTATGAMDYWGQGTLVTVSS 112 AA PAT REGION 1..112 note 68 source 1..112 mol_type protein organism synthetic construct DVVMTQTPLSLSVTLGQPASISCRSSQSLLHSNGNTYLHWYLQKPGQAPKLLIYKVSNRFSGVPDRFSGSGSGTDFTLKISRVEAEDVGVYFCSQSTHVPFTFGQGTKLEIK 117 AA PAT REGION 1..117 note 69 source 1..117 mol_type protein organism synthetic construct EVQLVESGGGLVKPGGSLRLSCAASGITFSSYAMSWVRQAPGKGLEWVASISSGGSTYYPDSVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCVAIWDGSSYGYWGQGTTVTVSS 112 AA PAT REGION 1..112 note 70 source 1..112 mol_type protein organism synthetic construct DIVMTQTPLSLSVTPGQPASISCKSGQSLVHSNGKTYLHWYLQKPGQSPQLLIYKVSNRFSGVPDRFSGSGSGTDFTLKISRVEAEDVGVYYCSQSTHVPFTFGQGTKLEIK 117 AA PAT REGION 1..117 note 71 source 1..117 mol_type protein organism synthetic construct EVQLVESGGGLVKPGGSLRLSCAASGFIFSSYAMSWVRQPPGKRLEWVASIGSGGTTYYPDSVRGRFTISRDNARNILYLQMRSLRAEDTAVYYCAAIWDGSSHGYWGQGTLLTVSS 112 AA PAT REGION 1..112 note 72 source 1..112 mol_type protein organism synthetic construct DVVMTQSPLSLPVTLGQPASISCRSSQNLVHSNGNTYLHWYLQRPGQSPQLLIYKVSNRFSGVPDRFSGSGSGTDFTLKISRVEAEDLGVYYCSQSTHVPYTFGPGTKLEIK 118 AA PAT REGION 1..118 note 73 source 1..118 mol_type protein organism synthetic construct EVQLVESGGGLVKPGGSLRLSCAASGFTFSSYAMSWVRQTPEKRLEWVASINSGGVTTYYPDSVKGRFTISRDNAINILYLQMRSLRSEDTALYYCAAIWDGSSHGYWGQGTLVTVSS 112 AA PAT REGION 1..112 note 74 source 1..112 mol_type protein organism synthetic construct DVVMTQSPLSLPVTLGQPASISCRSSQSLVHSNGNTYLHWYLQRPGQSPRLLIYKVSNRFSGVPDRFSGSGSGTDFTLKISRVEAEDFGVYFCSQSTHVPYTFGPGTKLEIK 116 AA PAT REGION 1..116 note 75 source 1..116 mol_type protein organism synthetic construct EVQLVESGGGLVQPGGSLKLSCAASGFTFSDAWMDWVRQAPGKGLEWVAEIRNKANNHATYFTESVKGRFTISRDDSKNTVYLQMNSLRAEDTAVYYCTTATFVYWGQGTLVTVSS 111 AA PAT REGION 1..111 note 76 source 1..111 mol_type protein organism synthetic construct DVVMTQSPLSLPVSLGDRASISCRSSQSLVRNGITYLHWYQQKPGQSPKLLIYKVSNRFSGVPDRFSGSGSGTDFTLKISSVEAEDFGVYYCSQTPHVPYTFGQGTKLEIK