141652 EP 21212124.8 2021-12-02 University of Copenhagen Peptide-drug conjugates for treatment of neurodegenerative diseases 9 40 AA PAT source 1..40 mol_type protein organism Homo sapiens VARIANT 2 note D-alanine, D-serine, alpha-aminoisobutyric acid, N-methyl-serine, glycine, or valine VARIANT 40 note L-penicillamine or L-homocysteine HAEGTFTSDVSSYLEEQAAKEFIAWLVKGGPSSGAPPPSC 31 AA PAT source 1..31 mol_type protein organism Homo sapiens HAEGTFTSDVSSYLEGQAAKEFIAWLVKGRG 39 AA PAT source 1..39 mol_type protein organism Homo sapiens HGEGTFTSDLSKQMEEEAVRLFIEWLKNGGPSSGAPPPS 42 AA PAT source 1..42 mol_type protein organism Homo sapiens YAEGTFISDYSIAMDKIHQQDFVNWLLAQKGKKNDWKHNITQ 40 AA PAT source 1..40 mol_type protein organism Homo sapiens VARIANT 2 note alpha-aminoisobutyric acid VARIANT 20 note alpha-aminoisobutyric acid VARIANT 40 note L-Penicillamine YGEGTFTSDYSIYLDKQAAKEFVNWLLAGGPSSGAPPPSC 39 AA PAT source 1..39 mol_type protein organism Homo sapiens VARIANT 2 note D-alanine, D-serine, alpha-aminoisobutyric acid, N-methyl-serine, glycine, or valine VARIANT 13 note D-alanine, D-serine, alpha-aminoisobutyric acid, N-methyl-serine, glycine, or valine YAEGTFTSDYSIALDKIAQKAFVQWLIAGGPSSGAPPPS 39 AA PAT source 1..39 mol_type protein organism Homo sapiens VARIANT 2 note D-alanine, D-serine, alpha-aminoisobutyric acid, N-methyl-serine, glycine, or valine HAQGTFTSDKSKYLDERAAQDFVQWLLDGGPSSGAPPPS 40 AA PAT source 1..40 mol_type protein organism Homo sapiens VARIANT 2 note D-alanine, D-serine, alpha-aminoisobutyric acid, N-methyl-serine, glycine, or valine VARIANT 1 note X is any natural or synthetic amino acid VARIANT 10 note X is any natural or synthetic amino acid VARIANT 12 note X is any natural or synthetic amino acid VARIANT 15 note X is any natural or synthetic amino acid VARIANT 16 note X is any natural or synthetic amino acid VARIANT 23 note X is any natural or synthetic amino acid VARIANT 24 note X is any natural or synthetic amino acid VARIANT 27 note X is any natural or synthetic amino acid VARIANT 28 note X is any natural or synthetic amino acid VARIANT 40 note L-penicillamine or L-homocysteine XAEGTFTSDXSXYLXXQAAKEFXXWLXXGGPSSGAPPPSC 10 AA PAT source 1..10 mol_type protein organism Homo sapiens GPSSGAPPPS