IL 2022-09-29 RAMOT/0120 PCT US 63249834 2021-09-29 RAMOT AT TEL-AVIV UNIVERSITY LTD. TREATMENT OF ELEVATED METABOLITE LEVELS USING NANO-CARRIERS 24 71 DNA PAT source 1..71 mol_type other DNA organism synthetic construct gcgcgttgtataacctcaataatatggtttgagggtgtctaccaggaaccgtaaattcctgattacaacgc 19 DNA PAT source 1..19 mol_type other DNA organism synthetic construct acatgaggatcacccatgt 240 DNA PAT source 1..240 mol_type other DNA organism synthetic construct cgcttccgtcaaacccctgcgcgttgtataacctcaataatatggtttgagggtgtctaccaggaaccgtaaattcctgattacaacgcaaaccggatgatagacctcacctccccgcccaatactgaaatctcattaatacgcatacccccactatacacacgcaatcaccacattagcacaatgaataatcatcgtacgggagaaaacattctaaacccacatgaggatcacccatgt 834 DNA PAT source 1..834 mol_type other DNA organism synthetic construct agccctcaaccggagtttgaagcatggcttctaactttactcagttcgttctcgtcgacaatggcggaactggcgacgtgactgtcgccccaagcaacttcgctaacggggtcgctgaatggatcagctctaactcgcgttcacaggcttacaaagtaacctgtagcgttcgtcagagctctgcgcagaatcgcaaatacaccatcaaagtcgaggtgcctaaagtggcaacccagactgttggtggtgtagagcttcctgtagccgcatggcgttcgtacttaaatatggaactaaccattccaattttcgctacgaattccgactgcgagcttattgttaaggcaatgcaaggtctcctaaaagatggaaacccgattccctcagcaatcgcagcaaactccggcatctacgctaactttactcagttcgttctcgtcgacaatggcggtacccatcaccatcaccatcacggtaccggcgacgtgactgtcgccccaagcaacttcgctaacggggtcgctgaatggatcagctctaactcgcgttcacaggcttacaaagtaacctgtagcgttcgtcagagctctgcgcagaatcgcaaatacaccatcaaagtcgaggtgcctaaagtggcaacccagactgttggtggtgtagagcttcctgtagccgcatggcgttcgtacttaaatatggaactaaccattccaattttcgctacgaattccgactgcgagcttattgttaaggcaatgcaaggtctcctaaaagatggaaacccgattccctcagcaatcgcagcaaactccggcatctactaatagacgccgg 1739 DNA PAT source 1..1739 mol_type other DNA organism synthetic construct acgactcactataggggaattgtgagcggataacaattcccctgtagaaataattttgtttaactttaataaggagatataccatggtggctatcgctgtaggtagccggaattccattcctaggaggtttgacctgtgcgagcttttagtacccttgatagggagaacgagaccttcgtcccctccgttcgcgtttacgcggacggtgagactgaagataactcattctctttaaaatatcgttcgaactggactcccggtcgttttaactcgactggggccaaaacgaaacagtggcactacccctctccgtattcacggggggcgttaagtgtcacatcgatagatcaaggtgcctacaagcgaagtgggtcatcgtggggtcgcccgtacgaggagaaagccggtttcggcttctccctcgacgcacgctcctgctacagcctcttccctgtaagccagaacttgacttacatcgaagtgccgcagaacgttgcgaaccgggcgtcgaccgaagtcctgcaaaaggtcacccagggtaattttaaccttggtgttgctttagcagaggccaggtcgacagcctcacaactcgcgacgcaaaccattgcgctcgtgaaggcgtacactgccgctcgtcgcggtaattggcgccaggcgctccgctaccttgccctaaacgaagatcgaaagtttcgatcaaaacacgtggccggcaggtggttggagttgcagttcggttggttaccactaatgagtgatatccagggtgcctatgagatgcttacgaaggttcaccttcaagagtttcttcctatgagagccgtacgtcaggtcggtactaacatcaagttaaatggccgtctgtcgtatccagctgcaaacttccagacaacgtgcaacatatcgcgacgtatcgtgatatggttttacataaacgatgcacgtttggcatggttgtcgtctctaggtatcttgaacccactaggtatagtgtgggaaaaggtgcctttctcattcgttgtcgactggctcctacctgtaggtaacatgctcgagggccttacggcccccgtgggatgctcctacatgtcaggaacagttactgacgtaataacgggtgagtccatcataagcgttgacgctccctacgggtggactgtggagagacagggcactgctaaggcccaaatctcagccatgcatcgaggggtacaatccgtatggccaacaactggcgcgtacgtaaagtctcctttctcgatggtccataccttagatgcgttagcattaatcaggcaacggctctctagatagagccctcaaccggagtttgaagcatggcttctaactttactcagttcgttctcgtcgacaatggcggaactggcgacgtgactgtcgccccaagcaacttcgctaacggggtcgctgaatggatcagctctaactcgcgttcacaggcttacaaagtaacctgtagcgttcgtcagagctctgcgcagaatcgcaaatacaccatcaaagtcgaggtgcctaaagtggcaacccagactgttggtggtgtagagcttcctgtagccgcatggcgttcgtacttaaatatggaactaaccattccaattttcgctacgaattccgactgcgagcttattgttaaggcaatgcaaggtctcctaaaagatggaaacccgattccctcagcaatcgcagcaaactccggcatctacgctaactt 240 RNA PAT source 1..240 mol_type other RNA organism synthetic construct cgcttccgtcaaacccctgcgcgttgtataacctcaataatatggtttgagggtgtctaccaggaaccgtaaattcctgattacaacgcaaaccggatgatagacctcacctccccgcccaatactgaaatctcattaatacgcatacccccactatacacacgcaatcaccacattagcacaatgaataatcatcgtacgggagaaaacattctaaacccacatgaggatcacccatgt 246 RNA PAT source 1..246 mol_type other RNA organism synthetic construct cgcgttgtataacctcaataatatggtttgagggtgtctaccaggaaccgtaaattcctgattacaacgccccctgcgcttccgtcaaacccctgaaaccggatgatagacctcacctccccgcccaatactgaaatctcattaatacgcatacccccactatacacacgcaatcaccacattagcacaatgaataatcatcgtacgggagaaaacattctaaacccacatgaggatcacccatgt 240 RNA PAT source 1..240 mol_type other RNA organism synthetic construct cgcttccgtcaaacccctgaaaccggatgatagacctcacctccccgcccaatactgaaatctcattaatacgcatacccccactatacacacgcaatcaccacattacgcgttgtataacctcaataatatggtttgagggtgtctaccaggaaccgtaaattcctgattacaacgcgcacaatgaataatcatcgtacgggagaaaacattctaaacccacatgaggatcacccatgt 242 RNA PAT source 1..242 mol_type other RNA organism synthetic construct cgcgttgtataacctcaataatatggtttgagggtgtctaccaggaaccgtaaattcctgattacaacgctttcagttagttaatgtatctactttctaaatattatatttgtatgtattttttgatactcaaatgaaatttgtattattaactaatataagttagtatcacattataagaaagcaaaaacaattcctgtataggtaagaaattgccaaaaaaacatgaggatcacccatgt 242 RNA PAT source 1..242 mol_type other RNA organism synthetic construct cgcgttgtataacctcaataatatggtttgagggtgtctaccaggaaccgtaaattcctgattacaacgctcgtactagatttttagatgattttcagaataattgcgctctattataacttaattagtacctaaagggtgaaacgtctaactattgaacaccctacgatgtctacatatgggcatagtaaaccagaatctcccccaatcgagtgtatattgtacatgaggatcacccatgt 242 RNA PAT source 1..242 mol_type other RNA organism synthetic construct cgcgttgtataacctcaataatatggtttgagggtgtctaccaggaaccgtaaattcctgattacaacgcaagaagttatagtggtaattttcccatgacaaggaccctatgaacttcataagtcaaatgtgtcatcttgttcatttgattgaaggatttaagacaataacgtcgtgctcgcgatcaactacccaaagacatcattgagcggggcaattttggacatgaggatcacccatgt 242 RNA PAT source 1..242 mol_type other RNA organism synthetic construct cgcgttgtataacctcaataatatggtttgagggtgtctaccaggaaccgtaaattcctgattacaacgccgccggaaccgtgctattgtgaaataaacacacgttcgggaaacaagggcacacatagcccagattcgcccacccaactgccagtgcccgagcttaccatattcgttctgtatgcagtgctgtaattgcgtgcacggaagattcattcttgcgacatgaggatcacccatgt 242 RNA PAT source 1..242 mol_type other RNA organism synthetic construct cgcgttgtataacctcaataatatggtttgagggtgtctaccaggaaccgtaaattcctgattacaacgccgaggaaatgcacacggagcttcccacatacgccgcccgcttacggccgtccgttccgactctaggacacgtaaaactcacccttacgctcacagcagtgaatcggggtagcaggcccccgaccgtccactcgcccgagcgagcggatgatgaacatgaggatcacccatgt 242 RNA PAT source 1..242 mol_type other RNA organism synthetic construct cgcgttgtataacctcaataatatggtttgagggtgtctaccaggaaccgtaaattcctgattacaacgcgatgccatgagccacgagggcgagtacgagctggtgggccctggcacttaacctgaactaggcggcaactttacgacgagagttcgtgactggccacgcggaacgcactccccgtacggagcctgcgcatcatgtcggaagcggggtgggctgacatgaggatcacccatgt 242 RNA PAT source 1..242 mol_type other RNA organism synthetic construct cgcgttgtataacctcaataatatggtttgagggtgtctaccaggaaccgtaaattcctgattacaacgccgtaagcgatcccggccacactgtcgggaggccgcctctgcctccggcttggcggccacccaggtatggagggttgcctgccggctgcgttcgcgccatcgctacgcgggcagcgggaggcaacgagccgacgtacgcccggctaggaatcccacatgaggatcacccatgt 242 RNA PAT source 1..242 mol_type other RNA organism synthetic construct cgcgttgtataacctcaataatatggtttgagggtgtctaccaggaaccgtaaattcctgattacaacgcaagccgacgctgcagtccggcgccgggagtggcggcccgccccccaccagtccctgggcgccgcggtggcctcatacggagccggcctggagccggcggggggcgctgcgccagcgctggcgcgttggggaccgggccgcgatcgtgcgcggcacatgaggatcacccatgt 130 AA PAT source 1..130 mol_type protein organism Emesvirus zinderi MASNFTQFVLVDNGGTGDVTVAPSNFANGVAEWISSNSRSQAYKVTCSVRQSSAQNRKYTIKVEVPKVATQTVGGVQLPVAAWRSYLNMELTIPIFATNDDCALIVKAMQGLLKDGNPIPSAIAANSGIY 12 RNA PAT source 1..12 mol_type other RNA organism synthetic construct cggggtgggctg 243 RNA PAT source 1..243 mol_type other RNA organism synthetic construct cgcgttgtataacctcaataatatggtttgagggtgtctaccaggaaccgtaaattcctgattacaacgctcgtactagatttttagatgattttcagaataattgcgctctattataacttaattagtacctaaagggtgaaacgtctaactattgaacaccctacgatgtctacatatgggcatagtaaaccagaatctcccccaatcgagtgtatgggctgacatgaggatcacccatgt 241 RNA PAT source 1..241 mol_type other RNA organism synthetic construct cgcgttgtataacctcaataatatggtttgagggtgtctaccaggaaccgtaaattcctgattacaacgctcgtactagatttttagatgattttcagaataattgcgctctattataacttaattagtacctaaagggtgaaacgtctaactattgaacaccctacgatgtctacatatgggcatagtaaaccagaatctcccccaatccggggtgggctgacatgaggatcacccatgt 242 RNA PAT source 1..242 mol_type other RNA organism synthetic construct cgcgttgtataacctcaataatatggtttgagggtgtctaccaggaaccgtaaattcctgattacaacgccgaggaaatgcacacggagcttcccacatacgccgcccgcttacggccgtccgttccgactctaggacacgtaaaactcacccttacgctcacagcagtgaatcggggtagcaggcccccgaccgtccactcgcccgagcccggggtgggctgacatgaggatcacccatgt 70 RNA PAT source 1..70 mol_type other RNA organism synthetic construct ccacttgccggtcctgtgagttaatagggaatccagtgcgaatctggagctgacgcgcagcggtaaggaa 242 RNA PAT source 1..242 mol_type other RNA organism synthetic construct ccacttgccggtcctgtgagttaatagggaatccagtgcgaatctggagctgacgcgcagcggtaaggaagagcgcggtgtggctggcgagcctaccgtgttggataaaggcacaggttttggtttaggggcgaccgtcacctttgtacccctattaccgaagcgctcggagcctagctgaacacttgttcagaaaaagccgagataaaactggcggcacggaacatgaggatcacccatgt 55 RNA PAT source 1..55 mol_type other RNA organism synthetic construct ggagagtgagtagaagcggtcagtgcaggcagctgcgcgggacattgctcagcaa