210855 1PCWO CN 202110178859.1 2021-02-09 Shanghai Junshi Biosciences Co., Ltd. ANTI-CD112R ANTIBODY AND USE THEREOF 150 5 AA PAT REGION 1..5 note HCDR1 source 1..5 mol_type protein organism synthetic construct NYNIH 17 AA PAT REGION 1..17 note HCDR2 source 1..17 mol_type protein organism synthetic construct YVYPYNGVPGYNQKFKS 9 AA PAT REGION 1..9 note HCDR3 source 1..9 mol_type protein organism synthetic construct ERGRDYFDS 11 AA PAT REGION 1..11 note LCDR1 source 1..11 mol_type protein organism synthetic construct RVSANIYSNLV 7 AA PAT REGION 1..7 note LCDR2 source 1..7 mol_type protein organism synthetic construct GGTNLAD 9 AA PAT REGION 1..9 note LCDR3 source 1..9 mol_type protein organism synthetic construct QHFWSTPYT 5 AA PAT REGION 1..5 note HCDR1 source 1..5 mol_type protein organism synthetic construct SHYMY 17 AA PAT REGION 1..17 note HCDR2 source 1..17 mol_type protein organism synthetic construct EINPSNGDTKFNEKFKS 10 AA PAT REGION 1..10 note HCDR3 source 1..10 mol_type protein organism synthetic construct EKDAFSALDY 11 AA PAT REGION 1..11 note LCDR1 source 1..11 mol_type protein organism synthetic construct RASQGIRGHLD 7 AA PAT REGION 1..7 note LCDR2 source 1..7 mol_type protein organism synthetic construct STSILNF 9 AA PAT REGION 1..9 note LCDR3 source 1..9 mol_type protein organism synthetic construct LQRNAYPLT 5 AA PAT REGION 1..5 note HCDR1 source 1..5 mol_type protein organism synthetic construct SYHMS 17 AA PAT REGION 1..17 note HCDR2 source 1..17 mol_type protein organism synthetic construct AINSNDINTYYLDTVKG 11 AA PAT REGION 1..11 note HCDR3 source 1..11 mol_type protein organism synthetic construct HEDYYGFAMDY 5 AA PAT REGION 1..5 note HCDR1 source 1..5 mol_type protein organism synthetic construct DYFIH 17 AA PAT REGION 1..17 note HCDR2 source 1..17 mol_type protein organism synthetic construct WIIPASGDTDCAPIFQG 10 AA PAT REGION 1..10 note HCDR3 source 1..10 mol_type protein organism synthetic construct WVWSPYAVDY 10 AA PAT REGION 1..10 note LCDR1 source 1..10 mol_type protein organism synthetic construct SATSSINYMH 7 AA PAT REGION 1..7 note LCDR2 source 1..7 mol_type protein organism synthetic construct DTSKLAS 9 AA PAT REGION 1..9 note LCDR3 source 1..9 mol_type protein organism synthetic construct QQWTSNPLT 5 AA PAT REGION 1..5 note HCDR1 source 1..5 mol_type protein organism synthetic construct NYIMS 17 AA PAT REGION 1..17 note HCDR2 source 1..17 mol_type protein organism synthetic construct TISSGGSSTYYVDRVKG 14 AA PAT REGION 1..14 note HCDR3 source 1..14 mol_type protein organism synthetic construct HEDWDPLYYYSMDY 10 AA PAT REGION 1..10 note LCDR1 source 1..10 mol_type protein organism synthetic construct SASSSVSYMY 7 AA PAT REGION 1..7 note LCDR2 source 1..7 mol_type protein organism synthetic construct DTSHLAF 9 AA PAT REGION 1..9 note LCDR3 source 1..9 mol_type protein organism synthetic construct QQWTTYPLT 5 AA PAT REGION 1..5 note HCDR1 source 1..5 mol_type protein organism synthetic construct DYFIH 17 AA PAT REGION 1..17 note HCDR2 source 1..17 mol_type protein organism synthetic construct WIIPASGDTDCAPIFQG 10 AA PAT REGION 1..10 note HCDR3 source 1..10 mol_type protein organism synthetic construct WVWSPYAVDY 17 AA PAT REGION 1..17 note LCDR1 source 1..17 mol_type protein organism synthetic construct KSSQSLLNSGNQKNFLA 7 AA PAT REGION 1..7 note LCDR2 source 1..7 mol_type protein organism synthetic construct GASTRES 9 AA PAT REGION 1..9 note LCDR3 source 1..9 mol_type protein organism synthetic construct QNDHSYPWT 5 AA PAT REGION 1..5 note HCDR1 source 1..5 mol_type protein organism synthetic construct DYNMH 17 AA PAT REGION 1..17 note HCDR2 source 1..17 mol_type protein organism synthetic construct YIYPYNGGTGHNQNFKS 10 AA PAT REGION 1..10 note HCDR3 source 1..10 mol_type protein organism synthetic construct EDFRHEKMDY 11 AA PAT REGION 1..11 note LCDR1 source 1..11 mol_type protein organism synthetic construct RTSDNIYVYLS 7 AA PAT REGION 1..7 note LCDR2 source 1..7 mol_type protein organism synthetic construct NAKTLTE 9 AA PAT REGION 1..9 note LCDR3 source 1..9 mol_type protein organism synthetic construct QHHYGTPYT 5 AA PAT REGION 1..5 note HCDR1 source 1..5 mol_type protein organism synthetic construct SYHMS 17 AA PAT REGION 1..17 note HCDR2 source 1..17 mol_type protein organism synthetic construct AISRDGDSTYYPDTVKG 11 AA PAT REGION 1..11 note HCDR3 source 1..11 mol_type protein organism synthetic construct HEDYFGFAMDS 11 AA PAT REGION 1..11 note LCDR1 source 1..11 mol_type protein organism synthetic construct KASQSVTNDVA 7 AA PAT REGION 1..7 note LCDR2 source 1..7 mol_type protein organism synthetic construct YVSNHYT 9 AA PAT REGION 1..9 note LCDR3 source 1..9 mol_type protein organism synthetic construct QQAYRSPWT 16 AA PAT REGION 1..16 note LCDR1 source 1..16 mol_type protein organism synthetic construct RSSQSIVHSNGNTYLH 7 AA PAT REGION 1..7 note LCDR2 source 1..7 mol_type protein organism synthetic construct KVSNRFS 9 AA PAT REGION 1..9 note LCDR3 source 1..9 mol_type protein organism synthetic construct FQGSHVPWT 5 AA PAT REGION 1..5 note HCDR1 source 1..5 mol_type protein organism synthetic construct SYHMS 17 AA PAT REGION 1..17 note HCDR2 source 1..17 mol_type protein organism synthetic construct AINSNVISTYYLDTVKG 11 AA PAT REGION 1..11 note HCDR3 source 1..11 mol_type protein organism synthetic construct HEDYYGFAMDY 11 AA PAT REGION 1..11 note LCDR1 source 1..11 mol_type protein organism synthetic construct KASQSVSNDVA 7 AA PAT REGION 1..7 note LCDR2 source 1..7 mol_type protein organism synthetic construct YVSHRFT 9 AA PAT REGION 1..9 note LCDR3 source 1..9 mol_type protein organism synthetic construct HQAYRSPWT 5 AA PAT REGION 1..5 note HCDR1 source 1..5 mol_type protein organism synthetic construct DYNMN 17 AA PAT REGION 1..17 note HCDR2 source 1..17 mol_type protein organism synthetic construct YIYPYNGGAGYNQNFKN 11 AA PAT REGION 1..11 note HCDR3 source 1..11 mol_type protein organism synthetic construct ERGMQRDYFDY 11 AA PAT REGION 1..11 note LCDR1 source 1..11 mol_type protein organism synthetic construct RTSENIYSNLA 7 AA PAT REGION 1..7 note LCDR2 source 1..7 mol_type protein organism synthetic construct AATNLAD 9 AA PAT REGION 1..9 note LCDR3 source 1..9 mol_type protein organism synthetic construct QHFWGTPYT 5 AA PAT REGION 1..5 note HCDR1 source 1..5 mol_type protein organism synthetic construct DYNIH 17 AA PAT REGION 1..17 note HCDR2 source 1..17 mol_type protein organism synthetic construct YNYPYNGGAGYNQNFRS 11 AA PAT REGION 1..11 note HCDR3 source 1..11 mol_type protein organism synthetic construct GEEVRRGPFYF 11 AA PAT REGION 1..11 note LCDR1 source 1..11 mol_type protein organism synthetic construct RTSENIYSFLV 7 AA PAT REGION 1..7 note LCDR2 source 1..7 mol_type protein organism synthetic construct NAKTLAE 9 AA PAT REGION 1..9 note LCDR3 source 1..9 mol_type protein organism synthetic construct QHYYGTPYT 5 AA PAT REGION 1..5 note HCDR1 source 1..5 mol_type protein organism synthetic construct SYHMS 17 AA PAT REGION 1..17 note HCDR2 source 1..17 mol_type protein organism synthetic construct AINSNGINTYYLDTVKG 11 AA PAT REGION 1..11 note HCDR3 source 1..11 mol_type protein organism synthetic construct HEDYYGFAMDY 11 AA PAT REGION 1..11 note LCDR1 source 1..11 mol_type protein organism synthetic construct KASQSVSNDVA 7 AA PAT REGION 1..7 note LCDR2 source 1..7 mol_type protein organism synthetic construct YVSNRFT 9 AA PAT REGION 1..9 note LCDR3 source 1..9 mol_type protein organism synthetic construct QQAYRSPWT 5 AA PAT REGION 1..5 note HCDR1 source 1..5 mol_type protein organism synthetic construct DYSMH 17 AA PAT REGION 1..17 note HCDR2 source 1..17 mol_type protein organism synthetic construct WISTETAQPTYADDFRG 10 AA PAT REGION 1..10 note HCDR3 source 1..10 mol_type protein organism synthetic construct TGNYGWYFSV 12 AA PAT REGION 1..12 note LCDR1 source 1..12 mol_type protein organism synthetic construct RATSGVSSSYLF 7 AA PAT REGION 1..7 note LCDR2 source 1..7 mol_type protein organism synthetic construct STSNLAS 9 AA PAT REGION 1..9 note LCDR3 source 1..9 mol_type protein organism synthetic construct QQYSGYPYT 5 AA PAT REGION 1..5 note HCDR1 source 1..5 mol_type protein organism synthetic construct DYPMS 16 AA PAT REGION 1..16 note HCDR2 source 1..16 mol_type protein organism synthetic construct CIDTDENTYYPDSVKG 11 AA PAT REGION 1..11 note HCR3 source 1..11 mol_type protein organism synthetic construct GWDDYAAWFAY 10 AA PAT REGION 1..10 note LCDR1 source 1..10 mol_type protein organism synthetic construct RASSSVNYMY 7 AA PAT REGION 1..7 note LCDR2 source 1..7 mol_type protein organism synthetic construct HTSNLAP 9 AA PAT REGION 1..9 note LCDR3 source 1..9 mol_type protein organism synthetic construct QQFTSSPWT 118 AA PAT REGION 1..118 note VH source 1..118 mol_type protein organism synthetic construct EVQLQQSGPELVKPGASVKISCKASGYPFINYNIHWLRQSRGKSLEWIGYVYPYNGVPGYNQKFKSKATLTADNSFSTAYMEFRSLTSEDSAVYFCARERGRDYFDSWGQGTSLTVSS 107 AA PAT REGION 1..107 note VL source 1..107 mol_type protein organism synthetic construct DIQLTQSPASLSVSVGETVTITCRVSANIYSNLVWYHQRQGKSPQLLVYGGTNLADGVPSRFSGSGSGTQFSLKINSLQSEDFGSYHCQHFWSTPYTFGGGTKLEIK 119 AA PAT REGION 1..119 note VH source 1..119 mol_type protein organism synthetic construct QVQLQQSGAELVKPGASVKLSCKASGYTFTSHYMYWLKQRPGQGLEWIGEINPSNGDTKFNEKFKSKATLTVDKSSSTAYMQLSSLTSEDSAVYYCTREKDAFSALDYWGQGTSVTDSS 107 AA PAT REGION 1..107 note VL source 1..107 mol_type protein organism synthetic construct DIQMIQSPSSMFASLGDRVSLSCRASQGIRGHLDWYQQKPGGTIKLLIYSTSILNFGVPSRFSGSGSGSDYSLTISSLESEDFADYYCLQRNAYPLTFGAGTKLELK 120 AA PAT REGION 1..120 note VH source 1..120 mol_type protein organism synthetic construct DVQLVESGGGLVKLGGSLKLSCVASGFTFSSYHMSWIRQTPEKRLELVAAINSNDINTYYLDTVKGRFTISRDIAKNTLHLQMSSLKSEDTALYYCARHEDYYGFAMDYWGQGTSVTVSS 107 AA PAT REGION 1..107 note VL source 1..107 mol_type protein organism synthetic construct DIQLTQSPASLSVSVGETVTITCRVSANIYSNLVWYHQRQGKSPQLLVYGGTNLADGVPSRFSGSGSGTQFSLKINSLQSEDFGSYHCQHFWSTPYTFGGGTKLEIK 119 AA PAT REGION 1..119 note VH source 1..119 mol_type protein organism synthetic construct EVQLQQSGAELVRSGTSVTLSCTASGFNIRDYFIHWVKQRPEQGLEWIGWIIPASGDTDCAPIFQGKATLTADTFSNTAYLHLNSLTSEDTAVYYCNTWVWSPYAVDYWGQGTSVTVSS 106 AA PAT REGION 1..106 note VL source 1..106 mol_type protein organism synthetic construct QIVLTQSPAIMSVSPGEKVTMTCSATSSINYMHWYQQKSGTSPKRWIYDTSKLASGVPARFSGSGSGTSYSLTISNMEAEDAATYYCQQWTSNPLTFGAGTKLELK 123 AA PAT REGION 1..123 note VH source 1..123 mol_type protein organism synthetic construct EVMLVESGGGLVKPGGSLKLSCAASGFTFSNYIMSWVRQTPDMRLEWVATISSGGSSTYYVDRVKGGFPFSRDSVKYILYVHTSSLRSADTAIYYCAKHEDWDPLYYYSMDYWGQGTSVTVSS 106 AA PAT REGION 1..106 note VL source 1..106 mol_type protein organism synthetic construct QIVLTQSPTVMSASPGDKVTMTCSASSSVSYMYWFQQKPGSSPRLLIYDTSHLAFGVPSRFSGSRSGTSYSLTISRMEAEDTATYYCQQWTTYPLTFGAGTKLELK 119 AA PAT REGION 1..119 note VH source 1..119 mol_type protein organism synthetic construct EVQLQQSGAELVRSGTSVTLSCTASGFNIRDYFIHWVKQRPEQGLEWIGWIIPASGDTDCAPIFQGKATLTADTFSNTAYLHLNSLTSEDTAVYYCNTWVWSPYAVDYWGQGTSVTVSS 113 AA PAT REGION 1..113 note VL source 1..113 mol_type protein organism synthetic construct DIVMTQFPSSLSVPVGEKVTMNCKSSQSLLNSGNQKNFLAWYQQKPGQPPKLLIYGASTRESGVPYRFTGSGSGTDFTLTISSVQAEDLAVYYCQNDHSYPWTFGGGTKLEIK 119 AA PAT REGION 1..119 note VH source 1..119 mol_type protein organism synthetic construct EVQLQQSGPELVKPGASVRISCKASGYTFTDYNMHWVKQSHGKSLEWIGYIYPYNGGTGHNQNFKSKATLTVDKSSSTAYMEFRSLTSDDSAVYYCAREDFRHEKMDYWGQGTSVTVSS 107 AA PAT REGION 1..107 note VL source 1..107 mol_type protein organism synthetic construct DIQMTQSPASLSASVGETVTITCRTSDNIYVYLSWYQQKQGKSPQLLVYNAKTLTENVPSRFSGSGSGTQFSLKINSLQPEDFGSYYCQHHYGTPYTFGGGTKLEIK 120 AA PAT REGION 1..120 note VH source 1..120 mol_type protein organism synthetic construct DVKLVESGGGLVKLGGSLKLSCAASGFTFSSYHMSWVRQTPEKRLELVAAISRDGDSTYYPDTVKGRFTISRDDAENTLYLQMSSLKSEDTALYYCSRHEDYFGFAMDSWGQGTSVTVSS 107 AA PAT REGION 1..107 note VL source 1..107 mol_type protein organism synthetic construct SIVMTQTPKFLLVSAGDRVTITCKASQSVTNDVAWYQQKPGQSPKLLMYYVSNHYTGVPDRFIGSGYGTDFTFTISTVQAEDLAVYFCQQAYRSPWTFGGGTKLEIK 119 AA PAT REGION 1..119 note VH source 1..119 mol_type protein organism synthetic construct EVQLQQSGAELVRSGTSVTLSCTASGFNIRDYFIHWVKQRPEQGLEWIGWIIPASGDTDCAPIFQGKATLTADTFSNTAYLHLNSLTSEDTAVYYCNTWVWSPYAVDYWGQGTSVTVSS 112 AA PAT REGION 1..112 note VL source 1..112 mol_type protein organism synthetic construct DVLMTQTPLSLPVSLGDQTSISCRSSQSIVHSNGNTYLHWYLQKPGQSPKLLIYKVSNRFSGVPDRFSGSGSGTDFTLKISRVEAEDLGVYYCFQGSHVPWTFGGGTRLEIK 120 AA PAT REGION 1..120 note VH source 1..120 mol_type protein organism synthetic construct DVKLVESGGGLVKLGGSLKLSCAASGFTFSSYHMSWVRQTPEKRLELVAAINSNVISTYYLDTVKGRFTISRDNAKNTLYLQMSSLKSEDTALYYCARHEDYYGFAMDYWGQGTSVTVSS 107 AA PAT REGION 1..107 note VL source 1..107 mol_type protein organism synthetic construct SIVMTQTPKFLLVSAGDRVTITCKASQSVSNDVAWYQEKPGQSPKLLMYYVSHRFTGVPDRFTGSGYGTDFTFTINTVQAEDLAVYFCHQAYRSPWTFGGGTKLEIK 120 AA PAT REGION 1..120 note VH source 1..120 mol_type protein organism synthetic construct EVQLQQSGPELVRPGASVRISCKASGYTFTDYNMNWVKQSHGKSLEWIGYIYPYNGGAGYNQNFKNKATLTVDTYSRAAYMELRSLTSEDSAVYYCARERGMQRDYFDYWGQGTILTVSS 107 AA PAT REGION 1..107 note VL source 1..107 mol_type protein organism synthetic construct DIQMTQSPASLSVSVGETVTITCRTSENIYSNLAWYQQKQGKSPQLLVYAATNLADGVPSRFSGSGSGTQFSLKINSLQSGDFGSYFCQHFWGTPYTFGGGTKLEIK 119 AA PAT REGION 1..119 note VH source 1..119 mol_type protein organism synthetic construct EVQLQQSGPELVKPGASVKISCKASGYTFTDYNIHWVKQSHGKRPDWIGYNYPYNGGAGYNQNFRSRATLTVDKFSSTAYMELRSLTSEDSAVYYCAGEEVRRGPFYFWGQGTSVTVSS 107 AA PAT REGION 1..107 note VL source 1..107 mol_type protein organism synthetic construct DIQMTQSPDSLSASVGETVTITCRTSENIYSFLVWYQQKQGKSPQLLVYNAKTLAEGVPSRFSGSGSGTQFSLKINSLQPEDFGTYYCQHYYGTPYTFGGGTKLEIK 120 AA PAT REGION 1..120 note VH source 1..120 mol_type protein organism synthetic construct DVKLVESGGGLVKLGGSLKLSCAASGFTFSSYHMSWIRQTPEKRLELVAAINSNGINTYYLDTVKGRFTISRDNAKNTLYLQMSSLKSEDTALYYCARHEDYYGFAMDYWGQGTSVTVSS 107 AA PAT REGION 1..107 note VL source 1..107 mol_type protein organism synthetic construct SIVMTQTPKFLLVSAGDRVTITCKASQSVSNDVAWYQQKPGQSPKLLMYYVSNRFTGVPDRFTGSGYGTDFTFTINTVQAEDLAVYFCQQAYRSPWTFGGGTKLEIK 118 AA PAT REGION 1..118 note VH source 1..118 mol_type protein organism synthetic construct QIQLVQSGPELKKPGETVKISCKASGYTFTDYSMHWVKQAPGKGLKWVGWISTETAQPTYADDFRGRFAFSLETSASTAYLQINNLRNEDTATYFCATGNYGWYFSVWGAGTTVTVSS 108 AA PAT REGION 1..108 note VL source 1..108 mol_type protein organism synthetic construct ENVLTQSPAIMSASPGEKVTMTCRATSGVSSSYLFWYQQKSGASPKIWIYSTSNLASGVPTRFSGSGSGTSYSLTISSVEAEDAATYYCQQYSGYPYTFGGGTKLEIK 119 AA PAT REGION 1..119 note VH source 1..119 mol_type protein organism synthetic construct EVKLVESGGGLVKPGGSLKVSCAASGFTFSDYPMSWVRQTPDKRLEWVACIDTDENTYYPDSVKGRFTISRDNGRNIVNLQMSSLRSEDAAMYYCARGWDDYAAWFAYWGQGTLVTVSA 106 AA PAT REGION 1..106 note VL source 1..106 mol_type protein organism synthetic construct ENVLTQFPAIMSVFLGERVTMSCRASSSVNYMYWYQQKSDASPKLWIYHTSNLAPGVPARFSGSGSGNSYSLTISSMEGEDAATYYCQQFTSSPWTFGGGTKLEIK 120 AA PAT REGION 1..120 note VH source 1..120 mol_type protein organism synthetic construct EVQLVESGGGLVQPGGSLRLSCAASGFTFSSYHMSWVRQAPGKGLELVAAINSNDINTYYLDTVKGRFTISRDIAKNSLYLQMNSLRAEDTAVYYCARHEDYYGFAMDYWGQGTLVTVSS 120 AA PAT REGION 1..120 note VH source 1..120 mol_type protein organism synthetic construct EVQLVESGGGLVKPGGSLRLSCAASGFTFSSYHMSWVRQAPGKGLELVSAINSNDINTYYLDTVKGRFTISRDIAKNSLYLQMNSLRAEDTAVYYCARHEDYYGFAMDYWGQGTLVTVSS 120 AA PAT REGION 1..120 note VH source 1..120 mol_type protein organism synthetic construct EVQLVESGGGLVKPGGSLRLSCAASGFTFSSYHMSWIRQAPGKGLELVSAINSNDINTYYLDTVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCARHEDYYGFAMDYWGQGTLVTVSS 120 AA PAT REGION 1..120 note VH source 1..120 mol_type protein organism synthetic construct EVQLVESGGGLVKPGGSLRLSCAASGFTFSSYHMSWVRQAPGKGLELVSAISRDGDSTYYPDTVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCSRHEDYFGFAMDSWGQGTLVTVSS 120 AA PAT REGION 1..120 note VH source 1..120 mol_type protein organism synthetic construct EVQLVESGGGLVKPGGSLRLSCAASGFTFSSYHMSWVRQAPGKGLELVSAISRDGDSTYYPDTVKGRFTISRDDAENSLYLQMNSLRAEDTAVYYCSRHEDYFGFAMDSWGQGTLVTVSS 120 AA PAT REGION 1..120 note VH source 1..120 mol_type protein organism synthetic construct EVQLVESGGGLVQPGGSLRLSCAASGFTFSSYHMSWVRQAPGKGLELVAAISRDGDSTYYPDTVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCSRHEDYFGFAMDSWGQGTLVTVSS 120 AA PAT REGION 1..120 note VH source 1..120 mol_type protein organism synthetic construct EVQLVESGGGLVQPGGSLRLSCAASGFTFSSYHMSWVRQAPGKGLELVAAISRDGDSTYYPDTVKGRFTISRDDAENSLYLQMNSLRAEDTAVYYCSRHEDYFGFAMDSWGQGTLVTVSS 107 AA PAT REGION 1..107 note VL source 1..107 mol_type protein organism synthetic construct DIVMTQSPDSLAVSLGERATINCKASQSVTNDVAWYQQKPGQPPKLLIYYVSNHYTGVPDRFSGSGSGTDFTLTISSLQAEDVAVYFCQQAYRSPWTFGQGTKLEIK 107 AA PAT REGION 1..107 note VL source 1..107 mol_type protein organism synthetic construct AIQMTQSPSSLSASVGDRVTITCKASQSVTNDVAWYQQKPGKAPKLLIYYVSNHYTGVPSRFSGSGSGTDFTLTISSLQPEDFATYFCQQAYRSPWTFGQGTKLEIK 120 AA PAT REGION 1..120 note VH source 1..120 mol_type protein organism synthetic construct EVQLVESGGGLVQPGGSLRLSCAASGFTFSSYHMSWVRQAPGKGLELVSAINSNVISTYYLDTVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCARHEDYYGFAMDYWGQGTLVTVSS 120 AA PAT REGION 1..120 note VH source 1..120 mol_type protein organism synthetic construct EVQLVESGGGLVKPGGSLRLSCAASGFTFSSYHMSWVRQAPGKGLELVSAINSNVISTYYLDTVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCARHEDYYGFAMDYWGQGTLVTVSS 107 AA PAT REGION 1..107 note VL source 1..107 mol_type protein organism synthetic construct EIVMTQSPPTLSLSPGERVTLSCKASQSVSNDVAWYQEKPGQAPRLLIYYVSHRFTGIPARFSGSGSGTDFTLTISSLQPEDFAVYYCHQAYRSPWTFGQGTKLEIK 107 AA PAT REGION 1..107 note VL source 1..107 mol_type protein organism synthetic construct DIVMTQSPDSLAVSLGERATINCKASQSVSNDVAWYQQKPGQPPKLLIYYVSHRFTGVPDRFSGSGSGTDFTLTISSLQAEDVAVYFCHQAYRSPWTFGQGTKLEIK 120 AA PAT REGION 1..120 note VH source 1..120 mol_type protein organism synthetic construct EVQLVESGGGLVKPGGSLRLSCAASGFTFSSYHMSWVRQAPGKGLELVSAINSNGINTYYLDTVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCARHEDYYGFAMDYWGQGTLVTVSS 120 AA PAT REGION 1..120 note VH source 1..120 mol_type protein organism synthetic construct EVQLVESGGGLVQPGGSLRLSCAASGFTFSSYHMSWIRQAPGKGLELVAAINSNGINTYYLDTVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCARHEDYYGFAMDYWGQGTLVTVSS 120 AA PAT REGION 1..120 note VH source 1..120 mol_type protein organism synthetic construct EVQLVESGGGLVQPGGSLRLSCAASGFTFSSYHMSWIRQAPGKGLELVAAINSNDINTYYLDTVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCARHEDYYGFAMDYWGQGTLVTVSS 107 AA PAT REGION 1..107 note VL source 1..107 mol_type protein organism synthetic construct DIQMTQSPSSLSASVGDRVTITCKASQSVSNDVAWYQQKPGKAPKLLIYYVSNRFTGVPSRFSGSGSGTDFTLTISSLQPEDFATYFCQQAYRSPWTFGQGTKLEIK 107 AA PAT REGION 1..107 note VL source 1..107 mol_type protein organism synthetic construct EIVMTQSPPTLSLSPGERVTLSCKASQSVSNDVAWYQQKPGQAPRLLIYYVSNRFTGIPARFSGSGSGTDFTLTISSLQPEDFAVYFCQQAYRSPWTFGQGTKLEIK 214 AA PAT REGION 1..214 note LC source 1..214 mol_type protein organism synthetic construct DIVMTQSPDSLAVSLGERATINCKASQSVSNDVAWYQQKPGQPPKLLIYYVSHRFTGVPDRFSGSGSGTDFTLTISSLQAEDVAVYFCHQAYRSPWTFGQGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 447 AA PAT REGION 1..447 note HC source 1..447 mol_type protein organism synthetic construct EVQLVESGGGLVKPGGSLRLSCAASGFTFSSYHMSWVRQAPGKGLELVSAISRDGDSTYYPDTVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCSRHEDYFGFAMDSWGQGTLVTVSSASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTKTYTCNVDHKPSNTKVDKRVESKYGPPCPPCPAPEFLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSQEDPEVQFNWYVDGVEVHNAKTKPREEQFNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKGLPSSIEKTISKAKGQPREPQVYTLPPSQEEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSRLTVDKSRWQEGNVFSCSVMHEALHNHYTQKSLSLSLGK 450 AA PAT REGION 1..450 note HC source 1..450 mol_type protein organism synthetic construct EVQLVESGGGLVKPGGSLRLSCAASGFTFSSYHMSWVRQAPGKGLELVSAISRDGDSTYYPDTVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCSRHEDYFGFAMDSWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK 214 AA PAT REGION 1..214 note LC source 1..214 mol_type protein organism synthetic construct DIVMTQSPDSLAVSLGERATINCKASQSVSNDVAWYQQKPGQPPKLLIYYVSHRFTGVPDRFSGSGSGTDFTLTISSLQAEDVAVYFCHQAYRSPWTFGQGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 447 AA PAT REGION 1..447 note HC source 1..447 mol_type protein organism synthetic construct EVQLVESGGGLVKPGGSLRLSCAASGFTFSSYHMSWVRQAPGKGLELVSAINSNGINTYYLDTVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCARHEDYYGFAMDYWGQGTLVTVSSASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTKTYTCNVDHKPSNTKVDKRVESKYGPPCPPCPAPEFLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSQEDPEVQFNWYVDGVEVHNAKTKPREEQFNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKGLPSSIEKTISKAKGQPREPQVYTLPPSQEEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSRLTVDKSRWQEGNVFSCSVMHEALHNHYTQKSLSLSLGK 450 AA PAT REGION 1..450 note HC source 1..450 mol_type protein organism synthetic construct EVQLVESGGGLVKPGGSLRLSCAASGFTFSSYHMSWVRQAPGKGLELVSAINSNGINTYYLDTVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCARHEDYYGFAMDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK 214 AA PAT REGION 1..214 note LC source 1..214 mol_type protein organism synthetic construct DIQMTQSPSSLSASVGDRVTITCKASQSVSNDVAWYQQKPGKAPKLLIYYVSNRFTGVPSRFSGSGSGTDFTLTISSLQPEDFATYFCQQAYRSPWTFGQGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 447 AA PAT REGION 1..447 note HC source 1..447 mol_type protein organism synthetic construct EVQLVESGGGLVQPGGSLRLSCAASGFTFSSYHMSWIRQAPGKGLELVAAINSNGINTYYLDTVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCARHEDYYGFAMDYWGQGTLVTVSSASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTKTYTCNVDHKPSNTKVDKRVESKYGPPCPPCPAPEFLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSQEDPEVQFNWYVDGVEVHNAKTKPREEQFNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKGLPSSIEKTISKAKGQPREPQVYTLPPSQEEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSRLTVDKSRWQEGNVFSCSVMHEALHNHYTQKSLSLSLGK 450 AA PAT REGION 1..450 note HC source 1..450 mol_type protein organism synthetic construct EVQLVESGGGLVQPGGSLRLSCAASGFTFSSYHMSWIRQAPGKGLELVAAINSNGINTYYLDTVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCARHEDYYGFAMDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK 121 AA PAT REGION 1..121 note VH source 1..121 mol_type protein organism synthetic construct EVQLQQSGAELVKPGASVKISCKASGYTFTDYNMDWVKQSHGKSLEWIGDIHPKYDRTSYNQNFKGKATLTVDKSSRTAYMELRSLTSEDTAVYFCVRINDFDEGFAMDYWGQGTSVTVSS 5 AA PAT REGION 1..5 note HCDR1 source 1..5 mol_type protein organism synthetic construct DYNMD 17 AA PAT REGION 1..17 note HCDR2 source 1..17 mol_type protein organism synthetic construct DIHPKYDRTSYNQNFKG 12 AA PAT REGION 1..12 note HCDR3 source 1..12 mol_type protein organism synthetic construct INDFDEGFAMDY 17 AA PAT REGION 1..17 note HCDR2 MUTAGEN 3 note Xaa is N or S MUTAGEN 4 note Xaa is S or R MUTAGEN 5 note Xaa is N or D MUTAGEN 6 note Xaa is D or G or V MUTAGEN 7 note Xaa is I or D MUTAGEN 8 note Xaa is N or S MUTAGEN 12 note Xaa is L or P source 1..17 mol_type protein organism synthetic construct AIXXXXXXTYYXDTVKG 11 AA PAT REGION 1..11 note HCDR3 MUTAGEN 5 note Xaa is Y or F MUTAGEN 11 note Xaa is Y or S source 1..11 mol_type protein organism synthetic construct HEDYXGFAMDX 11 AA PAT REGION 1..11 note LCDR1 MUTAGEN 7 note Xaa is T or S source 1..11 mol_type protein organism synthetic construct KASQSVXNDVA 7 AA PAT REGION 1..7 note LCDR2 MUTAGEN 4 note Xaa is N or H MUTAGEN 5 note Xaa is H or R MUTAGEN 6 note Xaa is Y or F source 1..7 mol_type protein organism synthetic construct YVSXXXT 9 AA PAT REGION 1..9 note LCDR3 MUTAGEN 1 note Xaa is Q or H source 1..9 mol_type protein organism synthetic construct XQAYRSPWT