CN GAI23CN02201P CN 2023105228812 2023-05-04 Xizang Haisco Pharmaceutical Co. , Ltd. Yao LI PREPARATION OF PEPTIDE INHIBITOR OF INTERLEUKIN-23 RECEPTOR AND USE THEREOF 3 13 AA PAT source 1..13 mol_type protein organism synthetic construct MOD_RES 1 note X is (Ac)Xa1, Xa1 is independently selected from Pen, Pcn, Asn, Ala, Ala (3-amino), Ala (2-ethene), Ala (3-azido), Ala (2-ethene), Val (2-ethene), 2,4-DIAMINO-BUTYRIC ACID, Ser, Cys, Hcys, Glu. MOD_RES 2 note X is selected from Asn, His or analogues of Asn and His. MOD_RES 4 note X is selected from Trp or its analogues. MOD_RES 5 note Lysine is acetylated. MOD_RES 6 note X is independently selected from Pen, Pcn, Asn, Ala, Ala (3-amino), Ala (2-ethene), Ala (3-azido), Ala (2-ethene), Val (2-ethene), 2,4-DIAMINO-BUTYRIC ACID, Ser, Cys, Hcys, Glu. MOD_RES 7 note X is selected from Phe or its analogues. MOD_RES 8 note X is selected from Phe, Trp, 2-Nal or analogues of Phe, Trp and 2-Nal. MOD_RES 9 note X is selected from Thp or its analogues. MOD_RES 12 note X is 3-Pal. MOD_RES 13 note X is Sarc(NH2). XXTXKXXXXENXX 13 AA PAT source 1..13 mol_type protein organism synthetic construct MOD_RES 1 note X is (Ac)Xa1, Xa1 is independently selected from Pen, Pcn, Asn, Ala, Ala (3-amino), Ala (2-ethene), Ala (3-azido), Ala (2-ethene), Val (2-ethene), 2,4-DIAMINO-BUTYRIC ACID, Ser, Cys, Hcys, Glu. MOD_RES 2 note X is selected from Asn, His or analogues of Asn and His. MOD_RES 4 note Tryptophan is methylated. MOD_RES 5 note Lysine is acetylated. MOD_RES 6 note X is independently selected from Pen, Pcn, Asn, Ala, Ala (3-amino), Ala (2-ethene), Ala (3-azido), Ala (2-ethene), Val (2-ethene), 2,4-DIAMINO-BUTYRIC ACID, Ser, Cys, Hcys, Glu. MOD_RES 7 note X is selected from Phe or its analogues. MOD_RES 8 note X is selected from Phe, Trp, 2-Nal or analogues of Phe, Trp and 2-Nal. MOD_RES 9 note X is selected from Thp or its analogues. MOD_RES 12 note X is 3-Pal. MOD_RES 13 note X is Sarc(NH2). XXTWKXXXXENXX 13 AA PAT source 1..13 mol_type protein organism synthetic construct MOD_RES 1 note X is independently selected from Pen, Pcn, Asn, Ala, Ala (3-amino), Ala (2-ethene), Ala (3-azido), Ala (2-ethene), Val (2-ethene), 2,4-DIAMINO-BUTYRIC ACID, Ser, Cys, Hcys, Glu. MOD_RES 4 note Tryptophan is methylated. MOD_RES 5 note Lysine is acetylated. MOD_RES 6 note X is independently selected from Pen, Pcn, Asn, Ala, Ala (3-amino), Ala (2-ethene), Ala (3-azido), Ala (2-ethene), Val (2-ethene), 2,4-DIAMINO-BUTYRIC ACID, Ser, Cys, Hcys, Glu. MOD_RES 7 note X is selected from Phe or its analogues. MOD_RES 8 note X is 2-Nal. MOD_RES 9 note X is selected from Thp or its analogues. MOD_RES 11 note X is selected from Asn, Lys or analogues of Asn and Lys. MOD_RES 12 note X is selected from 3-Pal, Phe, Asp or analogues of 3-Pal, Phe and Asp. MOD_RES 13 note X is Sarc. XNTWKXXXXEXXX