US us 63/364,734 2022-05-16 IL33-410-US-PSP[2] MEDIMMUNE LIMITED TREATMENT OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE WITH AN ANTI-INTERLEUKIN-33 ANTIBODY 11 5 AA PAT REGION 1..5 note Artificial Sequence source 1..5 mol_type protein organism synthetic construct SYAMS 17 AA PAT REGION 1..17 note Artificial Sequence source 1..17 mol_type protein organism synthetic construct GISAIDQSTYYADSVKG 17 AA PAT REGION 1..17 note Artificial Sequence source 1..17 mol_type protein organism synthetic construct QKFMQLWGGGLRYPFGY 126 AA PAT REGION 1..126 note Artificial Sequence source 1..126 mol_type protein organism synthetic construct EVQLLESGGGLVQPGGSLRLSCAASGFTFSSYAMSWVRQAPGKGLEWVSGISAIDQSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARQKFMQLWGGGLRYPFGYWGQGTMVTVSS 11 AA PAT REGION 1..11 note Artificial Sequence source 1..11 mol_type protein organism synthetic construct SGEGMGDKYAA 7 AA PAT REGION 1..7 note Artificial Sequence source 1..7 mol_type protein organism synthetic construct RDTKRPS 9 AA PAT REGION 1..9 note Artificial Sequence source 1..9 mol_type protein organism synthetic construct GVIQDNTGV 106 AA PAT REGION 1..106 note Artificial Sequence source 1..106 mol_type protein organism synthetic construct SYVLTQPPSVSVSPGQTASITCSGEGMGDKYAAWYQQKPGQSPVLVIYRDTKRPSGIPERFSGSNSGNTATLTISGTQAMDEADYYCGVIQDNTGVFGGGTKLTVL 212 AA PAT REGION 1..212 note Artificial Sequence source 1..212 mol_type protein organism synthetic construct SYVLTQPPSVSVSPGQTASITCSGEGMGDKYAAWYQQKPGQSPVLVIYRDTKRPSGIPERFSGSNSGNTATLTISGTQAMDEADYYCGVIQDNTGVFGGGTKLTVLGQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPTECS 456 AA PAT REGION 1..456 note Artificial Sequence source 1..456 mol_type protein organism synthetic construct EVQLLESGGGLVQPGGSLRLSCAASGFTFSSYAMSWVRQAPGKGLEWVSGISAIDQSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARQKFMQLWGGGLRYPFGYWGQGTMVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK 270 AA PAT source 1..270 mol_type protein organism Homo sapiens MKPKMKYSTNKISTAKWKNTASKALCFKLGKSQQKAKEVCPMYFMKLRSGLMIKKEACYFRRETTKRPSLKTGRKHKRHLVLAACQQQSTVECFAFGISGVQKYTRALHDSSITGISPITEYLASLSTYNDQSITFALEDESYEIYVEDLKKDEKKDKVLLSYYESQHPSNESGDGVDGKMLMVTLSPTKDFWLHANNKEHSVELHKCEKPLPDQAFFVLHNMHSNCVSFECKTDPGVFIGVKDNHLALIKVDSSENLCTENILFKLSET