US PCT/US2019/062547 2019-11-21 SP104015SGA US 62/770,631 2018-11-21 MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH Michael A BARRY ADENOVIRUSES AND METHODS FOR USING ADENOVIRUSES 65 12 AA PAT REGION 1..12 note targeting polypeptide source 1..12 mol_type protein organism synthetic construct TARGEHKEEELI 12 AA PAT REGION 1..12 note targeting polypeptide source 1..12 mol_type protein organism synthetic construct LRQTGAASAVWG 12 AA PAT REGION 1..12 note targeting polypeptide source 1..12 mol_type protein organism synthetic construct ARRADTQWRGLE 19 AA PAT REGION 1..19 note targeting polypeptide source 1..19 mol_type protein organism synthetic construct GTWLNPGFPPQSCGYATVT 9 AA PAT REGION 1..9 note targeting polypeptide source 1..9 mol_type protein organism synthetic construct CDCRGDCFC 10 AA PAT REGION 1..10 note targeting polypeptide source 1..10 mol_type protein organism synthetic construct NMSLDVNRKA 12 AA PAT REGION 1..12 note targeting polypeptide source 1..12 mol_type protein organism synthetic construct ISLSSHRATWVV 20 AA PAT REGION 1..20 note targeting polypeptide source 1..20 mol_type protein organism synthetic construct WTMGLDQLRDSSWAHGGFSA 20 AA PAT REGION 1..20 note targeting polypeptide source 1..20 mol_type protein organism synthetic construct WTMGLDQLRGDSSWAHGGFS 20 AA PAT REGION 1..20 note targeting polypeptide source 1..20 mol_type protein organism synthetic construct RSVSGTEWVPMNEQHRGAIW 20 AA PAT REGION 1..20 note targeting polypeptide source 1..20 mol_type protein organism synthetic construct TELRTHTSKELTIRTAASSD 20 AA PAT REGION 1..20 note targeting polypeptide source 1..20 mol_type protein organism synthetic construct DRAIGWQDKLYKLPLGSIHN 20 AA PAT REGION 1..20 note targeting polypeptide source 1..20 mol_type protein organism synthetic construct MGSWEKAALWNRVSASSGGA 20 AA PAT REGION 1..20 note targeting polypeptide source 1..20 mol_type protein organism synthetic construct MAMGGKPERPADSDNVQVRG 20 AA PAT REGION 1..20 note targeting polypeptide source 1..20 mol_type protein organism synthetic construct MASRGDAGEGSTQSNTNVPS 20 AA PAT REGION 1..20 note targeting polypeptide source 1..20 mol_type protein organism synthetic construct GPEDTSRAPENQQKTFHRRW 20 AA PAT REGION 1..20 note targeting polypeptide source 1..20 mol_type protein organism synthetic construct MGREDVGEQKLISEEDLGGS 11 AA PAT REGION 1..11 note targeting polypeptide source 1..11 mol_type protein organism synthetic construct ACDCRGDCFCG 12 AA PAT REGION 1..12 note targeting polypeptide source 1..12 mol_type protein organism synthetic construct ACDCREDVCFCG 20 AA PAT REGION 1..20 note targeting polypeptide source 1..20 mol_type protein organism synthetic construct GQIPITEPELCCVPWTEAFY 20 AA PAT REGION 1..20 note targeting polypeptide source 1..20 mol_type protein organism synthetic construct PQPPNSTAHPNPHKAPPNTT 20 AA PAT REGION 1..20 note targeting polypeptide source 1..20 mol_type protein organism synthetic construct VRWFPGGEWGVTHPESLPPP 19 AA PAT REGION 1..19 note targeting polypeptide source 1..19 mol_type protein organism synthetic construct KKKKKKKKKKKKKKKKKKK 14 AA PAT REGION 1..14 note targeting polypeptide source 1..14 mol_type protein organism synthetic construct GLNDIFEAQKIEWH 23 AA PAT REGION 1..23 note targeting polypeptide source 1..23 mol_type protein organism synthetic construct CAAARWKKAFIAVSAANRFKKIS 14 AA PAT REGION 1..14 note targeting polypeptide source 1..14 mol_type protein organism synthetic construct EDPGFFNVEIPEFP 20 AA PAT REGION 1..20 note targeting polypeptide source 1..20 mol_type protein organism synthetic construct GGHGRVLWPDGWFSLVGISP 21 AA PAT REGION 1..21 note targeting polypeptide source 1..21 mol_type protein organism synthetic construct MARTVTANVPGMGEGMVVVPC 20 AA PAT REGION 1..20 note targeting polypeptide source 1..20 mol_type protein organism synthetic construct GVSKRGLQCHDFISCSGVPW 20 AA PAT REGION 1..20 note targeting polypeptide source 1..20 mol_type protein organism synthetic construct NQSIPKVAGDSKVFCWWCAL 20 AA PAT REGION 1..20 note targeting polypeptide source 1..20 mol_type protein organism synthetic construct QSTPPTKHLTIPRHLRNTLI 20 AA PAT REGION 1..20 note targeting polypeptide source 1..20 mol_type protein organism synthetic construct DMSFQLVTPFLKALPTGWRG 20 AA PAT REGION 1..20 note targeting polypeptide source 1..20 mol_type protein organism synthetic construct GGHGRVLWPDGWFSLVGISP 8 AA PAT REGION 1..8 note targeting polypeptide source 1..8 mol_type protein organism synthetic construct FSLVGISP 20 AA PAT REGION 1..20 note targeting polypeptide source 1..20 mol_type protein organism synthetic construct QIMMGPSLGYYMPSESIFAY 20 AA PAT REGION 1..20 note targeting polypeptide source 1..20 mol_type protein organism synthetic construct ISWDIWRWWYTSEDRDAGSA 20 AA PAT REGION 1..20 note targeting polypeptide source 1..20 mol_type protein organism synthetic construct VWGMTTSDHQRKTERLDSPE 20 AA PAT REGION 1..20 note targeting polypeptide source 1..20 mol_type protein organism synthetic construct MTSAQTSEKLKAETDRHTAE 19 AA PAT REGION 1..19 note targeting polypeptide source 1..19 mol_type protein organism synthetic construct MGSRSAVGDFESAEGSRRP 20 AA PAT REGION 1..20 note targeting polypeptide source 1..20 mol_type protein organism synthetic construct MGRTVQSGDGTPAQTQPSVN 20 AA PAT REGION 1..20 note targeting polypeptide source 1..20 mol_type protein organism synthetic construct MARTVTANVPGMGEGMVVVP 132 AA PAT REGION 1..132 note Adenovirus E1A N-terminus polypeptide source 1..132 mol_type protein organism synthetic construct MRHIICHGGVITEEMAASLLDQLIEEVLADNLPPPSHFEPPTLHELYDLDVTAPEDPNEEAVSQIFPESVMLAVQEGIDLFTFPPAPGSPEPPHLSRQPEQPEQRALGPVSMPNLVPEVIDLTCHEAGFPPS 112 AA PAT REGION 1..112 note E1A N-terminus polypeptide source 1..112 mol_type protein organism synthetic construct MRHIEEVLADNLPPPSHFEPPTLHELYDLDVTAPEDPNEEAVSQIFPESVMLAVQEGIDLFTFPPAPGSPEPPHLSRQPEQPEQRALGPVSMPNLVPEVIDLTCHEAGFPPS 119 AA PAT REGION 1..119 note E1A N-terminus polypeptide source 1..119 mol_type protein organism synthetic construct MRHIICHGGVITEEMAASLLDQLIEEVLADNLPPPSHFEPPTLHELYDLDVTAPEDPNEEAVSQIFPESVMLAVQEGIDLFTFPPAPGSPEPPHLSRQPEQPEQRALGPVCHEAGFPPS 99 AA PAT REGION 1..99 note E1A N-terminus polypeptide source 1..99 mol_type protein organism synthetic construct MRHIEEVLADNLPPPSHFEPPTLHELYDLDVTAPEDPNEEAVSQIFPESVMLAVQEGIDLFTFPPAPGSPEPPHLSRQPEQPEQRALGPVCHEAGFPPS 5 AA PAT REGION 1..5 note Cell Binding Peptide source 1..5 mol_type protein organism synthetic construct REDVY 12 AA PAT REGION 1..12 note Breast Cancer Binding Peptide source 1..12 mol_type protein organism synthetic construct ISLSSHRATWVV 1608 AA PAT REGION 1..1608 note Probasin-E1 nucleic acid source 1..1608 mol_type protein organism synthetic construct TCGAGCGACGGTATCGATAAGCTTGGAGCTTATGATAGCATCTTGTTCTTAGTCTTTTTCTTAATAGGGACATAAAGCCCACAAATAAAAATATGCCTGAAGAATGGGACAGGCATTGGGCATTGTCCATGCCTAGTAAAGTACTCCAAGAACCTATTTGTATACTAGATGACACAATGTTCTAGCCAAGCTTGGTAGTCATCATGTTTAAACATCTACCATTCCAGTTAAGAAAATATGATAGCATCTTGTTCTTAGTCTTTTTCTTAATAGGGACATAAAGCCCACAAATAAAAATATGCCTGAAGAATGGGACAGGCATTGGGCATTGTCCATGCCTAGTAAAGTACTCCAAGAACCTATTTGTATACTAGATGACACAATGTCAATGTCTGTGTACAACTGCCAACTGGGATGCAAGACACTGCCCATGCCAATCATCCTGAAAAGCAGCTATAAAAAGCAGGAAGCTACTCTGCACCTTGTCAGTGAGGTCCAGATACCTCCCTCGAGCGGCCGCGACGCGCAGTGTATTTATACCCGGTGAGTTCCTCAAGAGGCCACTCTTGAGTGCCAGCGAGTAGAGTTTTCTCCTCCGAGCCGCTCCGACACCGGGACTGAAAATGAGACATATTATCTGCCACGGAGGTGTTATTACCGAAGAAATGGCCGCCAGTCTTTTGGACCAGCTGATCGAAGAGGTACTGGCTGATAATCTTCCACCTCCTAGCCATTTTGAACCACCTACCCTTCACGAACTGTATGATTTAGACGTGACGGCCCCCGAAGATCCCAACGAGGAGGCGGTTTCGCAGATTTTTCCCGAGTCTGTAATGTTGGCGGTGCAGGAAGGGATTGACTTATTCACTTTTCCGCCGGCGCCCGGTTCTCCGGAGCCGCCTCACCTTTCCCGGCAGCCCGAGCAGCCGGAGCAGAGAGCCTTGGGTCCGGTTTCTATGCCAAACCTTGTGCCGGAGGTGATCGATCTTACCTGCCACGAGGCTGGCTTTCCACCCAGTGACGACGAGGATGAAGAGGGTGAGGAGTTTGTGTTAGATTATGTGGAGCACCCCGGGCACGGTTGCAGGTCTTGTCATTATCACCGGAGGAATACGGGGGACCCAGATATTATGTGTTCGCTTTGCTATATGAGGACCTGTGGCATGTTTGTCTACAGTAAGTGAAAATTATGGGCAGTCGGTGATAGAGTGGTGGGTTTGGTGTGGTAATTTTTTTTTAATTTTTACAGTTTTGTGGTTTAAAGAATTTTGTATTGTGATTTTTTAAAAGGTCCTGTGTCTGAACCTGAGCCTGAGCCCGAGCCAGAACCGGAGCCTGCAAGACCTACCCGGCGTCCTAAATTGGTGCCTGCTATCCTGAGACGCCCGACATCACCTGTGTCTAGAGAATGCAATAGTAGTACGGATAGCTGTGACTCCGGTCCTTCTAACACACCTCCTGAGATACACCCGGTGGTCCCGCTGTGCCCCATTAAACCAGTTGCCGTGAGAGTTGGTGGGCGTCGCCAGGCTGTGGAATGTATCGAGGACTTGCTTAACGAGTCTGGGCAACCTTTGGACTTGAGCTGTAAACGCCCCAGGCCATAAG 959 AA PAT REGION 1..959 note Hexon Polypeptide source 1..959 mol_type protein organism synthetic construct MATPSMMPQWSYMHISGQDASEYLSPGLVQFARATETYFSLNNKFRNPTVAPTHDVTTDRSQRLTLRFIPVDREDTAYSYKARFTLAVGDNRVLDMASTYFDIRGVLDRGPTFKPYSGTAYNALAPKGAPNSCEWDEDDTQVQVAAEDDQDDDEEEEQLPQQRNGKKTHVYAQAPFAGEAINKNGLQIGTNGAATEGNKEIYADKTYQPEPQIGESQWNEAESSVAGGRVLKKTTPMKPCYGSYARPTNSNGGQGVMVEQNGKLESQVEMQFFSTSVNAMNEANAIQPKLVLYSEDVNMETPDTHLSYKPGKSDDNSKAMLGQQSMPNRPNYIAFRDNFIGLMYYNSTGNMGVLAGQASQLNAVVDLQDRNTELSYQLLLDSIGDRTRYFSMWNQAVDSYDPDVRIIENHGTEDELPNYCFPLGGIGVTDTYQAIKATNGNGGATTWAQDNTFAERNEIGVGNNFAMEINLNANLWRNFLYSNIALYLPDKLKYNPTNVEISDNPNTYDYMNKRVVAPGLVDCYINLGARWSLDYMDNVNPFNHHRNAGLRYRSMLLGNGRYVPFHIQVPQKFFAIKNLLLLPGSYTYEWNFRKDVNMVLQSSLGNDLRVDGASIKFDSICLYATFFPMAHNTASTLEAMLRNDTNDQSFNDYLSAANMLYPIPANATNVPISIPSRNWAAFRGWAFTRLKTKETPSLGSGYDPYYTYSGSIPYLDGTFYLNHTFKKVAITFDSSVSWPGNDRLLTPNEFEIKRSVDGEGYNVAQCNMTKDWFLVQMLANYNIGYQGFYIPESYKDRMYSFFRNFQPMSRQVVDDTKYKDYQQVGIIHQHNNSGFVGYLAPTMREGQAYPANVPYPLIGKTAVDSITQKKFLCDRTLWRIPFSSNFMSMGALTDLGQNLLYANSAHALDMTFEVDPMDEPTLLYVLFEVFDVVRVHQPHRGVIETVYLRTPFSAGNATT 967 AA PAT REGION 1..967 note Hexon Polypeptide source 1..967 mol_type protein organism synthetic construct MATPSMMPQWSYMHISGQDASEYLSPGLVQFARATETYFSLNNKFRNPTVAPTHDVTTDRSQRLTLRFIPVDREDTAYSYKARFTLAVGDNRVLDMASTYFDIRGVLDRGPTFKPYSGTAYNALAPKGAPNSCEWDEDDTQVQVAAEDDQDDDSSCSSGGTEEEEQLPQQRNGKKTHVYAQAPFAGEAINKNGLQIGTNGAATEGNKEIYADKTYQPEPQIGESQWNEAESSVAGGRVLKKTTPMKPCYGSYARPTNSNGGQGVMVEQNGKLESQVEMQFFSTSVNAMNEANAIQPKLVLYSEDVNMETPDTHLSYKPGKSDDNSKAMLGQQSMPNRPNYIAFRDNFIGLMYYNSTGNMGVLAGQASQLNAVVDLQDRNTELSYQLLLDSIGDRTRYFSMWNQAVDSYDPDVRIIENHGTEDELPNYCFPLGGIGVTDTYQAIKATNGNGGATTWAQDNTFAERNEIGVGNNFAMEINLNANLWRNFLYSNIALYLPDKLKYNPTNVEISDNPNTYDYMNKRVVAPGLVDCYINLGARWSLDYMDNVNPFNHHRNAGLRYRSMLLGNGRYVPFHIQVPQKFFAIKNLLLLPGSYTYEWNFRKDVNMVLQSSLGNDLRVDGASIKFDSICLYATFFPMAHNTASTLEAMLRNDTNDQSFNDYLSAANMLYPIPANATNVPISIPSRNWAAFRGWAFTRLKTKETPSLGSGYDPYYTYSGSIPYLDGTFYLNHTFKKVAITFDSSVSWPGNDRLLTPNEFEIKRSVDGEGYNVAQCNMTKDWFLVQMLANYNIGYQGFYIPESYKDRMYSFFRNFQPMSRQVVDDTKYKDYQQVGIIHQHNNSGFVGYLAPTMREGQAYPANVPYPLIGKTAVDSITQKKFLCDRTLWRIPFSSNFMSMGALTDLGQNLLYANSAHALDMTFEVDPMDEPTLLYVLFEVFDVVRVHQPHRGVIETVYLRTPFSAGNATT 955 AA PAT REGION 1..955 note Hexon Polypeptide source 1..955 mol_type protein organism synthetic construct MATPSMMPQWSYMHISGQDASEYLSPGLVQFARATETYFSLNNKFRNPTVAPTHDVTTDRSQRLTLRFIPVDREDTAYSYKARFTLAVGDNRVLDMASTYFDIRGVLDRGPTFKPYSGTAYNALAPKGAPNSCEWDEDDTQVQVAAEDDQDDDEEEEQLPQQRNGKKTHVYAQAPFAGEAINKNGLQIGTNGAATEGNKEIYADKTYQPEPQIGESQWNEAESSVAGGRVLKKTTPMKPCYGSYARPTNSNGGQGVMVEQNGKLESQVEMQFFSTSSCSSGGTPKLVLYSEDVNMETPDTHLSYKPGKSDDNSKAMLGQQSMPNRPNYIAFRDNFIGLMYYNSTGNMGVLAGQASQLNAVVDLQDRNTELSYQLLLDSIGDRTRYFSMWNQAVDSYDPDVRIIENHGTEDELPNYCFPLGGIGVTDTYQAIKATNGNGGATTWAQDNTFAERNEIGVGNNFAMEINLNANLWRNFLYSNIALYLPDKLKYNPTNVEISDNPNTYDYMNKRVVAPGLVDCYINLGARWSLDYMDNVNPFNHHRNAGLRYRSMLLGNGRYVPFHIQVPQKFFAIKNLLLLPGSYTYEWNFRKDVNMVLQSSLGNDLRVDGASIKFDSICLYATFFPMAHNTASTLEAMLRNDTNDQSFNDYLSAANMLYPIPANATNVPISIPSRNWAAFRGWAFTRLKTKETPSLGSGYDPYYTYSGSIPYLDGTFYLNHTFKKVAITFDSSVSWPGNDRLLTPNEFEIKRSVDGEGYNVAQCNMTKDWFLVQMLANYNIGYQGFYIPESYKDRMYSFFRNFQPMSRQVVDDTKYKDYQQVGIIHQHNNSGFVGYLAPTMREGQAYPANVPYPLIGKTAVDSITQKKFLCDRTLWRIPFSSNFMSMGALTDLGQNLLYANSAHALDMTFEVDPMDEPTLLYVLFEVFDVVRVHQPHRGVIETVYLRTPFSAGNATT 964 AA PAT REGION 1..964 note Hexon Polypeptide source 1..964 mol_type protein organism synthetic construct MATPSMMPQWSYMHISGQDASEYLSPGLVQFARATETYFSLNNKFRNPTVAPTHDVTTDRSQRLTLRFIPVDREDTAYSYKARFTLAVGDNRVLDMASTYFDIRGVLDRGPTFKPYSGTAYNALAPKGAPNSCEWDEDDTQVQVAAEDDQDDDSSGGTEEEEQLPQQRNGKKTHVYAQAPFAGEAINKNGLQIGTNGAATEGNKEIYADKTYQPEPQIGESQWNEAESSVAGGRVLKKTTPMKPCYGSYARPTNSNGGQGVMVEQNGKLESQVEMQFFSTSVNAMNEANAIQPKLVLYSEDVNMETPDTHLSYKPGKSDDNSKAMLGQQSMPNRPNYIAFRDNFIGLMYYNSTGNMGVLAGQASQLNAVVDLQDRNTELSYQLLLDSIGDRTRYFSMWNQAVDSYDPDVRIIENHGTEDELPNYCFPLGGIGVTDTYQAIKATNGNGGATTWAQDNTFAERNEIGVGNNFAMEINLNANLWRNFLYSNIALYLPDKLKYNPTNVEISDNPNTYDYMNKRVVAPGLVDCYINLGARWSLDYMDNVNPFNHHRNAGLRYRSMLLGNGRYVPFHIQVPQKFFAIKNLLLLPGSYTYEWNFRKDVNMVLQSSLGNDLRVDGASIKFDSICLYATFFPMAHNTASTLEAMLRNDTNDQSFNDYLSAANMLYPIPANATNVPISIPSRNWAAFRGWAFTRLKTKETPSLGSGYDPYYTYSGSIPYLDGTFYLNHTFKKVAITFDSSVSWPGNDRLLTPNEFEIKRSVDGEGYNVAQCNMTKDWFLVQMLANYNIGYQGFYIPESYKDRMYSFFRNFQPMSRQVVDDTKYKDYQQVGIIHQHNNSGFVGYLAPTMREGQAYPANVPYPLIGKTAVDSITQKKFLCDRTLWRIPFSSNFMSMGALTDLGQNLLYANSAHALDMTFEVDPMDEPTLLYVLFEVFDVVRVHQPHRGVIETVYLRTPFSAGNATT 952 AA PAT REGION 1..952 note Hexon Polypeptide source 1..952 mol_type protein organism synthetic construct MATPSMMPQWSYMHISGQDASEYLSPGLVQFARATETYFSLNNKFRNPTVAPTHDVTTDRSQRLTLRFIPVDREDTAYSYKARFTLAVGDNRVLDMASTYFDIRGVLDRGPTFKPYSGTAYNALAPKGAPNSCEWDEDDTQVQVAAEDDQDDDEEEEQLPQQRNGKKTHVYAQAPFAGEAINKNGLQIGTNGAATEGNKEIYADKTYQPEPQIGESQWNEAESSVAGGRVLKKTTPMKPCYGSYARPTNSNGGQGVMVEQNGKLESQVEMQFFSTSSGGTPKLVLYSEDVNMETPDTHLSYKPGKSDDNSKAMLGQQSMPNRPNYIAFRDNFIGLMYYNSTGNMGVLAGQASQLNAVVDLQDRNTELSYQLLLDSIGDRTRYFSMWNQAVDSYDPDVRIIENHGTEDELPNYCFPLGGIGVTDTYQAIKATNGNGGATTWAQDNTFAERNEIGVGNNFAMEINLNANLWRNFLYSNIALYLPDKLKYNPTNVEISDNPNTYDYMNKRVVAPGLVDCYINLGARWSLDYMDNVNPFNHHRNAGLRYRSMLLGNGRYVPFHIQVPQKFFAIKNLLLLPGSYTYEWNFRKDVNMVLQSSLGNDLRVDGASIKFDSICLYATFFPMAHNTASTLEAMLRNDTNDQSFNDYLSAANMLYPIPANATNVPISIPSRNWAAFRGWAFTRLKTKETPSLGSGYDPYYTYSGSIPYLDGTFYLNHTFKKVAITFDSSVSWPGNDRLLTPNEFEIKRSVDGEGYNVAQCNMTKDWFLVQMLANYNIGYQGFYIPESYKDRMYSFFRNFQPMSRQVVDDTKYKDYQQVGIIHQHNNSGFVGYLAPTMREGQAYPANVPYPLIGKTAVDSITQKKFLCDRTLWRIPFSSNFMSMGALTDLGQNLLYANSAHALDMTFEVDPMDEPTLLYVLFEVFDVVRVHQPHRGVIETVYLRTPFSAGNATT 1033 AA PAT REGION 1..1033 note Hexon Polypeptide source 1..1033 mol_type protein organism synthetic construct MATPSMMPQWSYMHISGQDASEYLSPGLVQFARATETYFSLNNKFRNPTVAPTHDVTTDRSQRLTLRFIPVDREDTAYSYKARFTLAVGDNRVLDMASTYFDIRGVLDRGPTFKPYSGTAYNALAPKGAPNSCEWDEDDTQVQVAAEDDQDDDSTGEIPAPLAGTVSKILVKEGDTVKAGQTVLVLEAMKMETEINAPTDGKVEKVLVKERDAVQGGQGLIKIGGGTEEEEQLPQQRNGKKTHVYAQAPFAGEAINKNGLQIGTNGAATEGNKEIYADKTYQPEPQIGESQWNEAESSVAGGRVLKKTTPMKPCYGSYARPTNSNGGQGVMVEQNGKLESQVEMQFFSTSVNAMNEANAIQPKLVLYSEDVNMETPDTHLSYKPGKSDDNSKAMLGQQSMPNRPNYIAFRDNFIGLMYYNSTGNMGVLAGQASQLNAVVDLQDRNTELSYQLLLDSIGDRTRYFSMWNQAVDSYDPDVRIIENHGTEDELPNYCFPLGGIGVTDTYQAIKATNGNGGATTWAQDNTFAERNEIGVGNNFAMEINLNANLWRNFLYSNIALYLPDKLKYNPTNVEISDNPNTYDYMNKRVVAPGLVDCYINLGARWSLDYMDNVNPFNHHRNAGLRYRSMLLGNGRYVPFHIQVPQKFFAIKNLLLLPGSYTYEWNFRKDVNMVLQSSLGNDLRVDGASIKFDSICLYATFFPMAHNTASTLEAMLRNDTNDQSFNDYLSAANMLYPIPANATNVPISIPSRNWAAFRGWAFTRLKTKETPSLGSGYDPYYTYSGSIPYLDGTFYLNHTFKKVAITFDSSVSWPGNDRLLTPNEFEIKRSVDGEGYNVAQCNMTKDWFLVQMLANYNIGYQGFYIPESYKDRMYSFFRNFQPMSRQVVDDTKYKDYQQVGIIHQHNNSGFVGYLAPTMREGQAYPANVPYPLIGKTAVDSITQKKFLCDRTLWRIPFSSNFMSMGALTDLGQNLLYANSAHALDMTFEVDPMDEPTLLYVLFEVFDVVRVHQPHRGVIETVYLRTPFSAGNATT 1021 AA PAT REGION 1..1021 note Hexon Polypeptide source 1..1021 mol_type protein organism synthetic construct MATPSMMPQWSYMHISGQDASEYLSPGLVQFARATETYFSLNNKFRNPTVAPTHDVTTDRSQRLTLRFIPVDREDTAYSYKARFTLAVGDNRVLDMASTYFDIRGVLDRGPTFKPYSGTAYNALAPKGAPNSCEWDEDDTQVQVAAEDDQDDDEEEEQLPQQRNGKKTHVYAQAPFAGEAINKNGLQIGTNGAATEGNKEIYADKTYQPEPQIGESQWNEAESSVAGGRVLKKTTPMKPCYGSYARPTNSNGGQGVMVEQNGKLESQVEMQFFSTSTGEIPAPLAGTVSKILVKEGDTVKAGQTVLVLEAMKMETEINAPTDGKVEKVLVKERDAVQGGQGLIKIGGGTPKLVLYSEDVNMETPDTHLSYKPGKSDDNSKAMLGQQSMPNRPNYIAFRDNFIGLMYYNSTGNMGVLAGQASQLNAVVDLQDRNTELSYQLLLDSIGDRTRYFSMWNQAVDSYDPDVRIIENHGTEDELPNYCFPLGGIGVTDTYQAIKATNGNGGATTWAQDNTFAERNEIGVGNNFAMEINLNANLWRNFLYSNIALYLPDKLKYNPTNVEISDNPNTYDYMNKRVVAPGLVDCYINLGARWSLDYMDNVNPFNHHRNAGLRYRSMLLGNGRYVPFHIQVPQKFFAIKNLLLLPGSYTYEWNFRKDVNMVLQSSLGNDLRVDGASIKFDSICLYATFFPMAHNTASTLEAMLRNDTNDQSFNDYLSAANMLYPIPANATNVPISIPSRNWAAFRGWAFTRLKTKETPSLGSGYDPYYTYSGSIPYLDGTFYLNHTFKKVAITFDSSVSWPGNDRLLTPNEFEIKRSVDGEGYNVAQCNMTKDWFLVQMLANYNIGYQGFYIPESYKDRMYSFFRNFQPMSRQVVDDTKYKDYQQVGIIHQHNNSGFVGYLAPTMREGQAYPANVPYPLIGKTAVDSITQKKFLCDRTLWRIPFSSNFMSMGALTDLGQNLLYANSAHALDMTFEVDPMDEPTLLYVLFEVFDVVRVHQPHRGVIETVYLRTPFSAGNATT 1015 AA PAT REGION 1..1015 note Hexon Polypeptide source 1..1015 mol_type protein organism synthetic construct MATPSMMPQWSYMHISGQDASEYLSPGLVQFARATETYFSLNNKFRNPTVAPTHDVTTDRSQRLTLRFIPVDREDTAYSYKARFTLAVGDNRVLDMASTYFDIRGVLDRGPTFKPYSGTAYNALAPKGAPNSCEWDEDDTQVQVAAEDDQDDDEEEEQLPQQRNGKKTHVYAQAPFAGEAINKNGLQIGTNGAATEGNKEIYADKTYQPEPQIGESQWNEAESSVAGGRVLKKTTPMKPCYGSYARPTNSNGGQGVMVEQNGKLESQVEMQFFSTSSSNFTREGNVTYKEEMDKVKNCSFNVTTGIRDKKQKVNALFYRLDITPLDENNNNSSEYRLINSGGTPKLVLYSEDVNMETPDTHLSYKPGKSDDNSKAMLGQQSMPNRPNYIAFRDNFIGLMYYNSTGNMGVLAGQASQLNAVVDLQDRNTELSYQLLLDSIGDRTRYFSMWNQAVDSYDPDVRIIENHGTEDELPNYCFPLGGIGVTDTYQAIKATNGNGGATTWAQDNTFAERNEIGVGNNFAMEINLNANLWRNFLYSNIALYLPDKLKYNPTNVEISDNPNTYDYMNKRVVAPGLVDCYINLGARWSLDYMDNVNPFNHHRNAGLRYRSMLLGNGRYVPFHIQVPQKFFAIKNLLLLPGSYTYEWNFRKDVNMVLQSSLGNDLRVDGASIKFDSICLYATFFPMAHNTASTLEAMLRNDTNDQSFNDYLSAANMLYPIPANATNVPISIPSRNWAAFRGWAFTRLKTKETPSLGSGYDPYYTYSGSIPYLDGTFYLNHTFKKVAITFDSSVSWPGNDRLLTPNEFEIKRSVDGEGYNVAQCNMTKDWFLVQMLANYNIGYQGFYIPESYKDRMYSFFRNFQPMSRQVVDDTKYKDYQQVGIIHQHNNSGFVGYLAPTMREGQAYPANVPYPLIGKTAVDSITQKKFLCDRTLWRIPFSSNFMSMGALTDLGQNLLYANSAHALDMTFEVDPMDEPTLLYVLFEVFDVVRVHQPHRGVIETVYLRTPFSAGNATT 987 AA PAT REGION 1..987 note Hexon Polypeptide source 1..987 mol_type protein organism synthetic construct MATPSMMPQWSYMHISGQDASEYLSPGLVQFARATETYFSLNNKFRNPTVAPTHDVTTDRSQRLTLRFIPVDREDTAYSYKARFTLAVGDNRVLDMASTYFDIRGVLDRGPTFKPYSGTAYNALAPKGAPNSCEWDEDDTQVQVAAEDDQDDDEEEEQLPQQRNGKKTHVYAQAPFAGEAINKNGLQIGTNGAATEGNKEIYADKTYQPEPQIGESQWNEAESSVAGGRVLKKTTPMKPCYGSYARPTNSNGGQGVMVEQNGKLESQVEMQFFSTSSQAEPDRAHYNIVTFCCKCDQLLRREVYDFAFRDLSGGTPKLVLYSEDVNMETPDTHLSYKPGKSDDNSKAMLGQQSMPNRPNYIAFRDNFIGLMYYNSTGNMGVLAGQASQLNAVVDLQDRNTELSYQLLLDSIGDRTRYFSMWNQAVDSYDPDVRIIENHGTEDELPNYCFPLGGIGVTDTYQAIKATNGNGGATTWAQDNTFAERNEIGVGNNFAMEINLNANLWRNFLYSNIALYLPDKLKYNPTNVEISDNPNTYDYMNKRVVAPGLVDCYINLGARWSLDYMDNVNPFNHHRNAGLRYRSMLLGNGRYVPFHIQVPQKFFAIKNLLLLPGSYTYEWNFRKDVNMVLQSSLGNDLRVDGASIKFDSICLYATFFPMAHNTASTLEAMLRNDTNDQSFNDYLSAANMLYPIPANATNVPISIPSRNWAAFRGWAFTRLKTKETPSLGSGYDPYYTYSGSIPYLDGTFYLNHTFKKVAITFDSSVSWPGNDRLLTPNEFEIKRSVDGEGYNVAQCNMTKDWFLVQMLANYNIGYQGFYIPESYKDRMYSFFRNFQPMSRQVVDDTKYKDYQQVGIIHQHNNSGFVGYLAPTMREGQAYPANVPYPLIGKTAVDSITQKKFLCDRTLWRIPFSSNFMSMGALTDLGQNLLYANSAHALDMTFEVDPMDEPTLLYVLFEVFDVVRVHQPHRGVIETVYLRTPFSAGNATT 959 AA PAT REGION 1..959 note Hexon Polypeptide source 1..959 mol_type protein organism synthetic construct MATPSMMPQWSYMHISGQDASEYLSPGLVQFARATETYFSLNNKFRNPTVAPTHDVTTDRSQRLTLRFIPVDREDTAYSYKARFTLAVGDNRVLDMASTYFDIRGVLDRGPTFKPYSGTAYNALAPKGAPNSCEWDEDDTQVQVAAEDDQDDDEEEEQLPQQRNGKKTHVYAQAPFAGEAINKNGLQIGTNGAATEGNKEIYADKTYQPEPQIGESQWNEAESSVAGGRVLKKTTPMKPCYGSYARPTNSNGGQGVMVEQNGKLESQVEMQFFSTSVNAMNEANAIQPKLVLYSEDVNMETPDTHLSYKPGKSDDNSKAMLGQQSMPNRPNYIAFRDNFIGLMYYNSTGNMGVLAGQASQLNAVVDLQDRNTELSYQLLLDSIGDRTRYFSMWNQAVDSYDPDVRIIENHGTEDELPNYCFPLGGIGVTDTYQAIKATNGNGGATTWAQDNTFAERNEIGVGNNFAMEINLNANLWRNFLYSNIALYLPDKLKYNPTNVEISDNPNTYDYMNKRVVAPGLVDCYINLGARWSLDYMDNVNPFNHHRNAGLRYRSMLLGNGRYVPFHIQVPQKFFAIKNLLLLPGSYTYEWNFRKDVNMVLQSSLGNDLRVDGASIKFDSICLYATFFPMAHNTASTLEAMLRNDTNDQSFNDYLSAANMLYPIPANATNVPISIPSRNWAAFRGWAFTRLKTKETPSLGSGYDPYYTYSGSIPYLDGTFYLNHTFKKVAITFDSSVSWPGNDRLLTPNEFEIKRSVDGEGYNVAQCNMTKDWFLVQMLANYNIGYQGFYIPESYKDRMYSFFRNFQPMSRQVVDDTKYKDYQQVGIIHQHNNSGFVGYLAPTMREGQAYPANVPYPLIGKTAVDSITQKKFLCDRTLWRIPFSSNFMSMGALTDLGQNLLYANSAHALDMTFEVDPMDEPTLLYVLFEVFDVVRVHQPHRGVIETVYLRTPFSAGNATT 962 AA PAT REGION 1..962 note Hexon Polypeptide source 1..962 mol_type protein organism synthetic construct MATPSMMPQWSYMHISGQDASEYLSPGLVQFARATETYFSLNNKFRNPTVAPTHDVTTDRSQRLTLRFIPVDREDTAYSYKARFTLAVGDNRVLDMASTYFDIRGVLDRGPTFKPYSGTAYNALAPKGAPNSCEWEQNETAQVDAQELDEEENEANEAQAREQEQAKKTHVYAQAPLSGEAINKNGLQIGTNGAATEGNKEIYADKTYQPEPQIGESQWNEAESSVAGGRVLKKTTPMKPCYGSYARPTNSNGGQGVMVEQNGKLESQVEMQFFSTSVNAMNEANAIQPKLVLYSEDVNMETPDTHLSYKPGKSDDNSKAMLGQQSMPNRPNYIAFRDNFIGLMYYNSTGNMGVLAGQASQLNAVVDLQDRNTELSYQLLLDSIGDRTRYFSMWNQAVDSYDPDVRIIENHGTEDELPNYCFPLGGIGITDTFQAVKTTAANGDQGNTTWQKDSTFAERNEIGVGNNFAMEINLNANLWRNFLYSNIALYLPDKLKYNPTNVEISDNPNTYDYMNKRVVAPGLVDCYINLGARWSLDYMDNVNPFNHPRHAGLRYRSMLLGNGRYVPFHIQVPQKFFAIKNLLLLPGSYTYEWNFRKDVNMVLQSSLGNDLRVDGASIKFDSICLYATFFPMAHNTASTLEAMLRNDTNDQSFNDYLSAANMLYPIPANATNVPISIPSRNWAAFRGWAFTRLKTKETPSLGSGYDPYYTYSGSIPYLDGTFYLNHTFKKVAITFDSSVSWPGNDRLLTPNEFEIKRSVDGEGYNVAQCNMTKDWFLVQMLANYNIGYQGFYIPESYKDRMYSFFRNFQPMSRQVVDDTKYKDYQQVGIIHQHNNSGFVGYLAPTMREGQAYPANVPYPLIGKTAVDSITQKKFLCDRTLWRIPFSSNFMSMGALTDLGQNLLYANSAHALDMTFEVDPMDEPTLLYVLFEVFDVVRVHQPHRGVIETVYLRTPFSAGNATT 528 AA PAT REGION 1..528 note Fiber Polypeptide source 1..528 mol_type protein organism synthetic construct MKRARPSEDTFNPVYPYDTETGPPTVPFLTPPFVSPNGFQESPPGVLSLRLSEPLVTSHGMLALKMGSGLSLDQAGNLTSNTITVSQPLKKTKSNITLETSAPLTVSSGALTMATTSPLVVSDNTLTMQSQAPLTVQDSKLSIATKEPLTVLDGKLALQTSAPLSATDNNALTITASPPLTTANGSLAVTMENPLYNNNGKLGLKIGGPLQVATDSHALTLGTGQGVAVHNNLLHTKVTGAIGFDTSGNMELKTGDGLYVDSAGPNQKLHINLNTTKGLAFDNTAITINAGKGLEFETDSSNGNPIKTKIGSGIQYNTNGAMVAKLGTGLSFDSSGAITMGSINNDRLTLWTTPDPSPNCRIASDKDCKLTLALTKCGSQILGTVSALAVSGNMASINGTLSSVNLVLRFDDNGVLMSNSSLDKQYWNFRNGDSTNGQPYTYAVGFMPNLKAYPKTQSKTAKSNIVSQVYLNGDKSKPLHFTITLNGTDETNQVSKYSISFSWSWNSGQYTNDKFATNSYTFSYIAQE 324 AA PAT REGION 1..324 note Fiber Polypeptide source 1..324 mol_type protein organism synthetic construct MKRARPSEDTFNPVYPYDTETGPPTVPFLTPPFVSPNGFQESPPGVLTLKCLTPLTTTGGSLQLKVGGGLTVDDTDGTLQENIRATAPITKNNHSVELSIGNGLETQNNKLCAKLGNGLKFNNGDICIKDSINTLWTGINPPPNCQIVENTNTNDGKLTLVLVKNGGLVNGYVSLVGVSDTVNQMFTQKTANIQLRLYFDSSGNLLTDESDLKIPLKNKSSTATSETVASSKAFMPSTTAYPFNTTTRDSENYIHGICYYMTSYDRSLFPLNISIMLNSRMISSNVAYAIQFEWNLNASESPESNIATLTTSPFFFSYITEDDN 534 AA PAT REGION 1..534 note Fiber Polypeptide source 1..534 mol_type protein organism synthetic construct MKRARPSEDTFNPVYPYDTETGPPTVPFLTPPFVSPNGFQESPPGVLSLRLSEPLVTSHGMLALKMGSGLSLDQAGNLTSNTITVSQPLKKTKSNITLETSAPLTVSSGALTMATTSPLVVSDNTLTMQSQAPLTVQDSKLSIATKEPLTVLDGKLALQTSAPLSATDNNALTITASPPLTTANGSLAVTMENPLYNNNGKLGLKIGGPLQVATDSHALTLGTGQGVAVHNNLLHTKVTGAIGFDTSGNMELKTGDGLYVDSAGPNQKLHINLNTTKGLAFDNTAITINAGKGLEFETDSSNGNPIKTKIGSGIQYNTNGAMVAKLGTGLSFDSSGAITMGSINNDRLTLWTTPDPSPNCRIASDKDCKLTLALTKCGSQILGTVSALAVSGNMASINGTLSSVNLVLRFDDNGVLMSNSSLDKQYWNFRNGDSTNGQPYTYAVGFMPNLKAYPKTQSKTAKSNIVSQVYLNGDKSKPLHFTITLNGTDETNQVSKYSISFSWSWNSGQYTNDKFATNSYTFSYIAQEKKKKKK 425 AA PAT REGION 1..425 note Fiber Polypeptide source 1..425 mol_type protein organism synthetic construct MKRARPSEDTFNPVYPYDTETGPPTVPFLTPPFVSPNGFQESPPGVLSLRLSEPLVTKNGEITLKLGEGVDLDSSGKLISNTATKAAAPLSFSNNTISLNMDHPFYTKDGKLSLQVSPPLNILRTSILNTLALGFGSGLGLRGSALAVQLVSPLTFDTDGNIKLTLDRGLHVTTGDAIESNISWAKGLKFEDGAIATNIGNGLEFGSSSTETGVDDAYPIQVKLGSGLSFDSTGAIMAGNKEDDKLTLWTTPDPSPNCQILAENDAKLTLCLTKCGSQILATVSVLVVGSGNLNPITGTVSSAQVFLRFDANGVLLTEHSTLKKYWGYRQGDSIDGTPYTNAVGFMPNLKAYPKSQSSTTKNNIVGQVYMNGDVSKPMLLTITLNGTDDSNSTYSMSFSYTWTNGSYVGATFGANSYTFSYIAQE 432 AA PAT REGION 1..432 note Fiber Polypeptide source 1..432 mol_type protein organism synthetic construct MKRARPSEDTFNPVYPYDTETGPPTVPFLTPPFVSPNGFQESPPGVLSLRLSEPLVTKNGEITLKLGEGVDLDSSGKLISNTATKAAAPLSFSNNTISLNMDHPFYTKDGKLSLQVSPPLNILRTSILNTLALGFGSGLGLRGSALAVQLVSPLTFDTDGNIKLTLDRGLHVTTGDAIESNISWAKGLKFEDGAIATNIGNGLEFGSSSTETGVDDAYPIQVKLGSGLSFDSTGAIMAGNKEDDKLTLWTTPDPSPNCQILAENDAKLTLCLTKCGSQILATVSVLVVGSGNLNPITGTVSSAQVFLRFDANGVLLTEHSTLKKYWGYRQGDSIDGTPYTNAVGFMPNLKAYPKSQSSTTKNNIVGQVYMNGDVSKPMLLTITLNGTDDSNSTYSMSFSYTWTNGSYVGATFGANSYTFSYIAQEKKKKKKK 441 AA PAT REGION 1..441 note Fiber Polypeptide source 1..441 mol_type protein organism synthetic construct MKRARPSEDTFNPVYPYDTETGPPTVPFLTPPFVSPNGFQESPPGVLSLRLSEPLVTKNGEITLKLGEGVDLDSSGKLISNTATKAAAPLSFSNNTISLNMDHPFYTKDGKLSLQVSPPLNILRTSILNTLALGFGSGLGLRGSALAVQLVSPLTFDTDGNIKLTLDRGLHVTTGDAIESNISWAKGLKFEDGAIATNIGNGLEFGSSSTETGVDDAYPIQVKLGSGLSFDSTGAIMAGNKEDDKLTLWTTPDPSPNCQILAENDAKLTLCLTKCGSQILATVSVLVVGSGNLNPITGTVSSAQVFLRFDANGVLLTEHSTLKKYWGYRQGDSIDGTPYTNAVGFMPNLKAYPKSQSSTTKNNIVGQVYMNGDVSKPMLLTITLNGTDDSGGSSGKKKKKKKASGGSSTYSMSFSYTWTNGSYVGATFGANSYTFSYIAQE