32328/55328P3 Amgen Inc. METHODS OF TREATING CANCER 10 7 AA PAT REGION 1..7 note Synthetic Polypeptide- HCDR1 source 1..7 mol_type protein organism synthetic construct SGDYYWT 16 AA PAT REGION 1..16 note Synthetic Polypeptide - HCDR2 source 1..16 mol_type protein organism synthetic construct HIYYSGNTNYNPSLKS 9 AA PAT REGION 1..9 note Synthetic Polypeptide- HCDR3 source 1..9 mol_type protein organism synthetic construct DRVTGAFDI 119 AA PAT REGION 1..119 note Synthetic Polypeptide -Heavy variable source 1..119 mol_type protein organism synthetic construct QVQLQESGPGLVKPSETLSLTCTVSGGSVSSGDYYWTWIRQSPGKGLEWIGHIYYSGNTNYNPSLKSRLTISIDTSKTQFSLKLSSVTAADTAIYYCVRDRVTGAFDIWGQGTMVTVSS 444 AA PAT REGION 1..444 note Synthetic Polypeptide -Heavy chain source 1..444 mol_type protein organism synthetic construct QVQLQESGPGLVKPSETLSLTCTVSGGSVSSGDYYWTWIRQSPGKGLEWIGHIYYSGNTNYNPSLKSRLTISIDTSKTQFSLKLSSVTAADTAIYYCVRDRVTGAFDIWGQGTMVTVSSASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSNFGTQTYTCNVDHKPSNTKVDKTVERKCCVECPPCPAPPVAGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVQFNWYVDGVEVHNAKTKPREEQFNSTFRVVSVLTVVHQDWLNGKEYKCKVSNKGLPAPIEKTISKTKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPMLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPG 11 AA PAT REGION 1..11 note Synthetic Polypeptide- LCDR1 source 1..11 mol_type protein organism synthetic construct QASQDISNYLN 7 AA PAT REGION 1..7 note Synthetic Polypeptide - LCDR2 source 1..7 mol_type protein organism synthetic construct DASNLET 9 AA PAT REGION 1..9 note Synthetic Polypeptide - LCDR3 source 1..9 mol_type protein organism synthetic construct QHFDHLPLA 110 AA PAT REGION 1..110 note Synthetic Polypeptide- Light variable source 1..110 mol_type protein organism synthetic construct DIQMTQSPSSLSASVGDRVTITCQASQDISNYLNWYQQKPGKAPKLLIYDASNLETGVPSRFSGSGSGTDFTFTISSLQPEDIATYFCQHFDHLPLAFGGGTKVEIKRTV 214 AA PAT REGION 1..214 note Synthetic Polypeptide- Light chain source 1..214 mol_type protein organism synthetic construct DIQMTQSPSSLSASVGDRVTITCQASQDISNYLNWYQQKPGKAPKLLIYDASNLETGVPSRFSGSGSGTDFTFTISSLQPEDIATYFCQHFDHLPLAFGGGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC