SG P25GZ1NW00053SG CN 2023100774548 2023-01-17 GUANGDONG RAYNOVENT BIOTECH CO., LTD. Guangdong Raynovent Biotechnology Co., Ltd CHEN Xiaoxin Xiaoxin Chen POLYPEPTIDE HAVING MODIFIED STRUCTURE AND USE THEREOF 43 39 AA PAT source 1..39 mol_type protein organism synthetic construct SITE 2 note X is Aib SITE 13 note L is alpha- Methylleucine SITE 20 note X is Aib YXQGTFTSDYSILLDKKAQXKFIEYLLEGGPSSGAPPPS 39 AA PAT source 1..39 mol_type protein organism synthetic construct SITE 2 note X is Aib SITE 13 note L is alpha- Methylleucine SITE 20 note X is Aib YXQGTFTSDYSILLDKKAQXAFIKWLLKGGPSSGAPPPS 39 AA PAT source 1..39 mol_type protein organism synthetic construct SITE 2 note X is Aib SITE 30 note X is Aib SITE 13 note L is alpha- Methylleucine YXQGTFTSDYSILLDKKAQXAFIEKLLEGGPSSGAPPPS 39 AA PAT source 1..39 mol_type protein organism synthetic construct SITE 2 note X is Aib SITE 20 note X is Aib HXHGTFTSDYSIYLEKKYAXEFVKWLLKGGPSSGAPPPS 39 AA PAT source 1..39 mol_type protein organism synthetic construct SITE 2 note X is Aib SITE 20 note X is Aib HXHGTFTSDYSIYLEKKYAXKFVQWLLEGGPSSGAPPPS 39 AA PAT source 1..39 mol_type protein organism synthetic construct SITE 2 note X is Aib SITE 20 note X is Aib SITE 13 note L is alpha- Methylleucine YXQGTFTSDYSILLDKKAQXAFIQKLLKGGPSSGAPPPS 39 AA PAT source 1..39 mol_type protein organism synthetic construct SITE 2 note X is Aib SITE 20 note X is Aib SITE 13 note L is alpha- Methylleucine YXQGTFTSDYSILLDKQAQXAFIEKLLKGGPSSGAPPPS 39 AA PAT source 1..39 mol_type protein organism synthetic construct SITE 2 note X is Aib SITE 20 note X is Aib SITE 13 note L is alpha- Methylleucine YXQGTFTSDYSILLDKEAQXAFIEKLLKGGPSSGAPPPS 39 AA PAT source 1..39 mol_type protein organism synthetic construct SITE 2 note X is Aib SITE 20 note X is Aib SITE 13 note L is alpha- Methylleucine HXQGTFTSDYSILLDKKAQXAFIEKLLKGGPSSGAPPPS 39 AA PAT source 1..39 mol_type protein organism synthetic construct SITE 2 note X is Aib SITE 20 note X is Aib SITE 13 note L is alpha- Methylleucine YXQGTFTSDYSILLDKKYQXAFIEKLLKGGPSSGAPPPS 39 AA PAT source 1..39 mol_type protein organism synthetic construct SITE 2 note X is Aib SITE 20 note X is Aib SITE 13 note L is alpha- Methylleucine YXQGTFTSDYSILLEKKAQXAFIEKLLKGGPSSGAPPPS 39 AA PAT source 1..39 mol_type protein organism synthetic construct SITE 2 note X is Aib SITE 20 note X is Aib HXHGTFTSDYSIYLEKKYAXEFVQELLKGGPSSGAPPPS 39 AA PAT source 1..39 mol_type protein organism synthetic construct SITE 2 note X is Aib SITE 20 note X is Aib SITE 13 note L is alpha- Methylleucine YXQGTFTSDYSILLDKKAQXAFIEELLKGGPSSGAPPPS 39 AA PAT source 1..39 mol_type protein organism synthetic construct SITE 2 note X is Aib SITE 20 note X is Aib SITE 13 note L is alpha- Methylleucine YXQGTFTSDYSILLDKKAQXAFIEWLLKGGPSSGAPPPS 39 AA PAT source 1..39 mol_type protein organism synthetic construct SITE 2 note X is Aib SITE 20 note X is Aib SITE 13 note L is alpha- Methylleucine YXQGTFTSDYSILLDKKAQXKFIEFLLEGGPSSGAPPPS 39 AA PAT source 1..39 mol_type protein organism synthetic construct SITE 2 note X is Aib SITE 20 note X is Aib SITE 13 note L is alpha- Methylleucine YXQGTFTSDYSILLDKKAQXEFIEYLLEGGPSSGAPPPS 39 AA PAT source 1..39 mol_type protein organism synthetic construct SITE 2 note X is Aib SITE 20 note X is Aib SITE 13 note L is alpha- Methylleucine YXQGTFTSDYSILLDKKAQXAFIKYLLEGGPSSGAPPPS 39 AA PAT source 1..39 mol_type protein organism synthetic construct SITE 2 note X is Aib SITE 20 note X is Aib SITE 13 note L is alpha- Methylleucine YXQGTFTSDYSILLDKKAQXKFIEYLLEGGPSSGAPPPS 39 AA PAT source 1..39 mol_type protein organism synthetic construct SITE 2 note X is Aib SITE 20 note X is Aib SITE 13 note L is alpha- Methylleucine YXQGTFTSDYSILLDKKAKXAFIKYLLEGGPSSGAPPPS 39 AA PAT source 1..39 mol_type protein organism synthetic construct SITE 2 note X is Aib SITE 20 note X is Aib SITE 13 note L is alpha- Methylleucine YXQGTFTSDYSILLDKKAQXKFIEYLLKGGPSSGAPPPS 39 AA PAT source 1..39 mol_type protein organism synthetic construct SITE 2 note X is Aib SITE 13 note L is alpha- Methylleucine SITE 21 note K is alpha- Methyllysine YXQGTFTSDYSILLDKKAQAKFIEYLLEGGPSSGAPPPS 39 AA PAT source 1..39 mol_type protein organism synthetic construct SITE 2 note X is Aib SITE 20 note X is Aib SITE 13 note L is alpha- Methylleucine SITE 21 note K is D-lysine YXQGTFTSDYSILLDKKAQXKFIEYLLEGGPSSGAPPPS 39 AA PAT source 1..39 mol_type protein organism synthetic construct SITE 2 note X is Aib SITE 20 note X is Aib SITE 13 note L is alpha- Methylleucine SITE 21 note X is L-Ornithine YXQGTFTSDYSILLDKKAQXXFIEYLLEGGPSSGAPPPS 39 AA PAT source 1..39 mol_type protein organism synthetic construct SITE 2 note X is Aib SITE 20 note X is Aib SITE 13 note L is alpha- Methylleucine YXQGTFTSDYSILKDKKAQXAFIEYLLEGGPSSGAPPPS 39 AA PAT source 1..39 mol_type protein organism synthetic construct SITE 2 note X is Aib SITE 20 note X is Aib SITE 13 note L is alpha- Methylleucine YXQGTFTSDYSILLDKKAQXKFIEFLLEGGPSSGAPPPS 39 AA PAT source 1..39 mol_type protein organism synthetic construct SITE 2 note X is Aib SITE 20 note X is Aib SITE 13 note is alpha- Methylleucine YXQGTFTSDYSILLDKKAQXKFIEFLIEGGPSSGAPPPS 39 AA PAT source 1..39 mol_type protein organism synthetic construct SITE 2 note X is Aib SITE 20 note X is Aib SITE 13 note L is alpha- Methylleucine YXQGTFTSDYSILLDKKAQXKFVEFLIEGGPSSGAPPPS 39 AA PAT source 1..39 mol_type protein organism synthetic construct SITE 2 note X is Aib SITE 20 note X is Aib SITE 13 note L is alpha- Methylleucine YXQGTFTSDYSILLDKKAQXAFIEKFIKGGPSSGAPPPS 39 AA PAT source 1..39 mol_type protein organism synthetic construct SITE 2 note X is Aib SITE 20 note X is Aib SITE 13 note L is alpha- Methylleucine YXQGTFTSDYSILLDKKAQXKFIEFLLKGGPSSGAPPPS 39 AA PAT source 1..39 mol_type protein organism synthetic construct SITE 2 note X is Aib SITE 13 note X is Aib SITE 20 note X is Aib YXQGTFTSDYSIXLDKKAQXKFIEFLLEGGPSSGAPPPS 39 AA PAT source 1..39 mol_type protein organism synthetic construct SITE 2 note X is Aib SITE 20 note X is Aib SITE 13 note L is alpha- Methylleucine YXQGTFTSDYSKLLDKKAQXAFIEFLLEGGPSSGAPPPS 39 AA PAT source 1..39 mol_type protein organism synthetic construct SITE 2 note X is Aib SITE 20 note X is Aib SITE 13 note L is alpha- Methylleucine YXQGTFTSDYSILLDKKAQXKFVEFLLKGGPSSGAPPPS 39 AA PAT source 1..39 mol_type protein organism synthetic construct SITE 2 note X is Aib SITE 20 note X is Aib SITE 13 note L is alpha- Methylleucine YXQGTFTSDYSILLDKKAQXKFVEFLIKGGPSSGAPPPS 39 AA PAT source 1..39 mol_type protein organism synthetic construct SITE 2 note X is Aib SITE 20 note X is Aib SITE 13 note L is alpha- Methylleucine YXQGTFTSDYSILLDKKAQXKFIEFLLKGGPSSGAPPPS 39 AA PAT source 1..39 mol_type protein organism synthetic construct SITE 2 note X is Aib SITE 20 note X is Aib SITE 13 note L is alpha- Methylleucine YXQGTFTSDYSILLDKKAQXKFIKFLLEGGPSSGAPPPS 39 AA PAT source 1..39 mol_type protein organism synthetic construct SITE 2 note X is Aib SITE 20 note X is Aib SITE 13 note L is alpha- Methylleucine YXQGTFTSDYSKLLDKKAQXKFIEFLLEGGPSSGAPPPS 39 AA PAT source 1..39 mol_type protein organism synthetic construct SITE 2 note X is Aib SITE 20 note X is Aib SITE 13 note L is alpha- Methylleucine YXQGTFTSDYSILKDKKAQXEFIEYLLEGGPSSGAPPPS 39 AA PAT source 1..39 mol_type protein organism synthetic construct SITE 2 note X is Aib SITE 20 note X is Aib SITE 13 note L is alpha- Methylleucine YXQGTFTSDYSILKDKKAQXAFIEYLLKGGPSSGAPPPS 39 AA PAT source 1..39 mol_type protein organism synthetic construct SITE 2 note X is Aib SITE 20 note X is Aib SITE 13 note L is alpha- Methylleucine YXQGTFTSDYSILKDKKAQXAFIQYLLEGGPSSGAPPPS 39 AA PAT source 1..39 mol_type protein organism synthetic construct SITE 2 note X is Aib SITE 20 note X is Aib SITE 13 note L is alpha- Methylleucine YXQGTFTSDYSILKDKKAQXKFIEYLLEGGPSSGAPPPS 39 AA PAT source 1..39 mol_type protein organism synthetic construct SITE 2 note X is Aib SITE 20 note X is Aib SITE 13 note L is alpha- Methylleucine YXQGTFTSDYSILKDKKAQXLFIEYLLEGGPSSGAPPPS 39 AA PAT source 1..39 mol_type protein organism synthetic construct SITE 2 note X is Aib SITE 20 note X is Aib SITE 6 note F is alpha- Methylphenylalanine SITE 13 note L is alpha- Methylleucine YXQGTFTSDYSILKDKKAQXAFIEYLLEGGPSSGAPPPS 39 AA PAT source 1..39 mol_type protein organism synthetic construct SITE 2 note X is Aib SITE 20 note X is Aib SITE 13 note L is alpha- Methylleucine SITE 6 note F is alpha- Methylphenylalanine YXQGTFTSDYSILKDKKAQXAFIEYLLKGGPSSGAPPPS